Flexeril and Lyrica drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Flexeril and Lyrica together. This review analyzes the effectiveness and drug interactions between Flexeril and Lyrica. It is created by eHealthMe based on reports of 3,634 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Flexeril and Lyrica, find out what symptoms you could have in 1 year or longer.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,897 users)

Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 126,941 users)

On Feb, 04, 2017

3,634 people who take Flexeril, Lyrica are studied.


Number of reports submitted per year:

Flexeril and Lyrica drug interactions.

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • drug ineffective
  • pain
  • somnolence
  • vision blurred
  • nausea
  • dyspnoea
  • dry mouth
  • oedema peripheral
  • weight decreased
1 - 6 months:
  • pain
  • anxiety
  • weight increased
  • drug ineffective
  • depression
  • insomnia
  • back pain
  • nausea
  • feeling abnormal
  • pain in extremity
6 - 12 months:
  • anxiety
  • pain
  • confusional state
  • insomnia
  • multi-organ failure
  • neutropenia
  • septic shock
  • weight decreased
  • withdrawal syndrome
  • amnesia
1 - 2 years:
  • pain
  • drug ineffective
  • malaise
  • depression
  • insomnia
  • headache
  • nausea
  • anxiety
  • burning sensation
  • gait disturbance
2 - 5 years:
  • pain
  • depression
  • drug ineffective
  • anxiety
  • feeling abnormal
  • weight increased
  • insomnia
  • malaise
  • withdrawal syndrome
  • paranoia
5 - 10 years:
  • pain
  • weight increased
  • blood cholesterol increased
  • depression
  • feeling abnormal
  • blood thyroid stimulating hormone increased
  • drug ineffective
  • erythema
  • hypertension
  • insomnia
10+ years:
  • back pain
  • malaise
  • pain
  • seizure
  • tremor
  • abdominal pain
  • abdominal pain lower
  • amnesia
  • arrhythmia
  • asthenia
not specified:
  • pain
  • drug ineffective
  • fatigue
  • nausea
  • arthralgia
  • weight increased
  • back pain
  • fall
  • anxiety
  • depression

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • weight increased
  • fatigue
  • nausea
  • arthralgia
  • fall
  • anxiety
  • pain in extremity
  • back pain
male:
  • pain
  • drug ineffective
  • depression
  • anxiety
  • dyspnoea
  • nausea
  • fatigue
  • back pain
  • neuropathy peripheral
  • dizziness

Most common drug interactions by age *:

0-1:
  • death
  • foetal exposure during pregnancy
10-19:
  • convulsion
  • drug ineffective
  • dyspnoea
  • hypoaesthesia
  • hypokinesia
  • musculoskeletal pain
  • musculoskeletal stiffness
  • abdominal pain upper
  • agitation
  • alanine aminotransferase increased
20-29:
  • pain in extremity
  • depression
  • pulmonary embolism
  • pain
  • back pain
  • hypoaesthesia
  • nausea
  • chest pain
  • feeling abnormal
  • insomnia
30-39:
  • pain
  • drug ineffective
  • depression
  • weight increased
  • arthralgia
  • nausea
  • abdominal pain upper
  • feeling abnormal
  • vomiting
  • completed suicide
40-49:
  • pain
  • drug ineffective
  • weight increased
  • arthralgia
  • depression
  • fatigue
  • nausea
  • anxiety
  • headache
  • muscle spasms
50-59:
  • pain
  • fatigue
  • drug ineffective
  • nausea
  • anxiety
  • weight increased
  • back pain
  • arthralgia
  • fall
  • hypoaesthesia
60+:
  • pain
  • dyspnoea
  • fall
  • anxiety
  • pain in extremity
  • nausea
  • dizziness
  • arthralgia
  • back pain
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Lyrica?

Interactions between Flexeril and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Lyrica and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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