Flexeril and Melatonin drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Flexeril and Melatonin together. This review analyzes the effectiveness and drug interactions between Flexeril and Melatonin. It is created by eHealthMe based on reports of 326 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Flexeril and Melatonin, find out what symptoms you could have in 1 year or longer.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,901 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 9,321 users)

On Feb, 11, 2017

326 people who take Flexeril, Melatonin are studied.


Number of reports submitted per year:

Flexeril and Melatonin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • behcet's syndrome
  • cataract
  • chest pain
  • cough
  • depression
  • diarrhoea
  • drug ineffective
  • dysgeusia
  • melanosis coli
  • overdose
1 - 6 months:
  • back pain
  • derealisation
  • drug hypersensitivity
  • migraine
  • paralysis
  • paranoia
  • seizure
6 - 12 months:
  • gastritis haemorrhagic
  • confusional state
  • enuresis
  • feeling abnormal
  • fluid retention
  • headache
  • nerve compression
  • neuropathy peripheral
  • sleep apnoea syndrome
  • urinary hesitation
1 - 2 years:
  • hypertension
  • abdominal discomfort
  • anxiety
  • depression
  • disturbance in attention
  • drug ineffective
  • fatigue
  • hypothyroidism
  • influenza like illness
  • irritability
2 - 5 years:
  • viral infection
  • abdominal discomfort
  • ankylosing spondylitis
  • anxiety
  • arthralgia
  • asthma
  • chest pain
  • constipation
  • depression
  • disturbance in attention
10+ years:
  • ankylosing spondylitis
  • arthralgia
  • asthma
  • chest pain
  • constipation
  • dyspnoea
  • fall
  • kidney infection
  • lyme disease
  • rash
not specified:
  • pain
  • fatigue
  • depression
  • drug ineffective
  • insomnia
  • nausea
  • pain in extremity
  • diarrhoea
  • back pain
  • fall

Most common drug interactions by gender *:

female:
  • drug ineffective
  • fatigue
  • pain
  • insomnia
  • nausea
  • depression
  • arthralgia
  • fall
  • muscle spasms
  • back pain
male:
  • pain
  • diarrhoea
  • pain in extremity
  • fatigue
  • depression
  • anxiety
  • nephrolithiasis
  • back pain
  • anaemia
  • osteomyelitis

Most common drug interactions by age *:

0-1:
  • herpes zoster
10-19:
  • viral infection
  • non-alcoholic steatohepatitis
  • weight increased
  • hyporesponsive to stimuli
  • intentional overdose
  • agitation
  • alanine aminotransferase increased
  • aphasia
  • appetite disorder
  • aspartate aminotransferase increased
20-29:
  • back pain
  • bipolar i disorder
  • blood cholesterol increased
  • chronic obstructive pulmonary disease
  • depression
  • fatigue
  • gastrooesophageal reflux disease
  • hypoaesthesia
  • hypothyroidism
  • influenza like illness
30-39:
  • pain
  • arthralgia
  • depression
  • blood creatinine increased
  • pruritus
  • rash
  • accident at work
  • anger
  • cervicobrachial syndrome
  • cough
40-49:
  • fatigue
  • pain
  • depression
  • anxiety
  • tooth infection
  • back pain
  • cellulitis
  • abdominal neoplasm
  • anaemia
  • b-cell lymphoma recurrent
50-59:
  • drug ineffective
  • fatigue
  • back pain
  • insomnia
  • pain
  • muscle spasms
  • depression
  • diarrhoea
  • pain in extremity
  • nausea
60+:
  • drug ineffective
  • myocardial infarction
  • nausea
  • weight decreased
  • fall
  • fatigue
  • muscle spasms
  • pneumonia
  • pain in extremity
  • cough

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Melatonin?

Interactions between Flexeril and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Melatonin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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