Review: taking Flexeril and Ritalin together


Summary

Drug interactions are reported among people who take Flexeril and Ritalin together. This review analyzes the effectiveness and drug interactions between Flexeril and Ritalin. It is created by eHealthMe based on reports of 258 people who take the same drugs from FDA and social media, and is updated regularly.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 16,144 users)

Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 11,167 users)

On Jul, 21, 2016

258 people who take Flexeril, Ritalin are studied.


Number of reports submitted per year:

Flexeril and Ritalin drug interactions.

Drug effectiveness over time:

Flexeril:
  • < 1 month: 12.0% - (1 of 8 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Ritalin:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 40.0% - (4 of 10 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 100.0% - (3 of 3 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Flexeril:
  • female: 31.0% - (6 of 19 people)
  • male: 0.0% - (0 of 6 people)
Ritalin:
  • female: 52.0% - (10 of 19 people)
  • male: 37.0% - (3 of 8 people)

Drug effectiveness by age:

Flexeril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 28.0% - (2 of 7 people)
  • 60+: 0.0% - (0 of 1 people)
Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 20.0% - (1 of 5 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 57.0% - (4 of 7 people)
  • 40-49: 100.0% - (3 of 3 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • actinic keratosis
  • dehydration
  • nausea
  • sweating increased
  • food poisoning
  • vomiting
1 - 6 months:
  • insomnia
  • anger
  • clonus
  • depression
  • diarrhoea
  • fever
  • gastritis
  • headache
  • major depression
  • mood swings
6 - 12 months:
  • depression
  • insomnia
  • migraine hemiplegic
1 - 2 years:
  • insomnia
  • migraine hemiplegic
  • tonic seizures
2 - 5 years:
  • mouth dry aggravated
  • alopecia
  • balance disorder
  • chronic fatigue syndrome
  • clonus
  • cough
  • decreased appetite
  • decreased interest
  • depression aggravated
  • diarrhoea
5 - 10 years:
  • alopecia
  • anger
  • balance disorder
  • cough
  • decreased appetite
  • decreased interest
  • depression aggravated
  • diarrhoea
  • dizziness postural
  • dry mouth
10+ years:
  • itching
  • mouth dry aggravated
  • chronic fatigue syndrome
  • diarrhoea
  • dry eyes aggravated
  • excessive bronchial secretion
  • fever
  • gastritis
  • headache
  • high blood pressure
not specified:
  • fatigue
  • back pain
  • fall
  • dyspnoea
  • anaemia
  • weight decreased
  • tenderness
  • headache
  • constipation
  • osteomyelitis

Most common drug interactions by gender *:

female:
  • fatigue
  • back pain
  • fall
  • dyspnoea
  • headache
  • tenderness
  • weight decreased
  • constipation
  • anaemia
  • osteomyelitis
male:
  • nausea
  • vomiting
  • fatigue
  • anaemia
  • hyperhidrosis
  • asthenia
  • back pain
  • dyspnoea
  • fall
  • atelectasis

Most common drug interactions by age *:

10-19:
  • cardio-respiratory arrest
  • congenital ectodermal dysplasia
  • diabetes mellitus
  • diabetic complication
  • diabetic ketoacidosis
  • hepatic steatosis
  • pulmonary congestion
  • pulmonary oedema
  • cardiac arrest
  • hepatic congestion
20-29:
  • blood cholesterol increased
  • diabetes mellitus
  • dizziness
  • extrapyramidal disorder
  • glycosuria
  • hyperglycaemia
  • postural orthostatic tachycardia syndrome
  • tremor
  • type 2 diabetes mellitus
  • deep vein thrombosis
30-39:
  • diabetes mellitus
  • insomnia
  • suicidal ideation
  • suicide attempt
  • bipolar disorder
  • depression
  • diabetic neuropathy
  • obesity
  • pneumonia
  • post-traumatic stress disorder
40-49:
  • anxiety
  • pain
  • atelectasis
  • head injury
  • hypotension
  • back pain
  • constipation
  • depression
  • dyspnoea
  • insomnia
50-59:
  • fall
  • fatigue
  • headache
  • pain
  • back pain
  • dizziness
  • diarrhoea
  • nausea
  • hypoaesthesia
  • paraesthesia
60+:
  • back pain
  • arthralgia
  • tenderness
  • dyspnoea
  • fatigue
  • osteoarthritis
  • anaemia
  • chronic obstructive pulmonary disease
  • deep vein thrombosis
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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