Review: taking Flexeril and Ritalin together


Summary

Drug interactions are reported among people who take Flexeril and Ritalin together. This review analyzes the effectiveness and drug interactions between Flexeril and Ritalin. It is created by eHealthMe based on reports of 469 people who take the same drugs from FDA and social media, and is updated regularly.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,055 users)

Ritalin

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 14,979 users)

On Sep, 17, 2016

469 people who take Flexeril, Ritalin are studied.


Number of reports submitted per year:

Flexeril and Ritalin drug interactions.

Drug effectiveness over time:

Flexeril:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Ritalin:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 44.0% - (4 of 9 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 100.0% - (3 of 3 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Flexeril:
  • female: 30.0% - (6 of 20 people)
  • male: 0.0% - (0 of 5 people)
Ritalin:
  • female: 52.0% - (11 of 21 people)
  • male: 33.0% - (2 of 6 people)

Drug effectiveness by age:

Flexeril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 16.0% - (1 of 6 people)
  • 60+: 0.0% - (0 of 1 people)
Ritalin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 25.0% - (1 of 4 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 50.0% - (3 of 6 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • back disorder
  • actinic keratosis
  • back pain
  • dehydration
  • nausea
  • neuralgia
  • pain
  • pulmonary mass
  • pulmonary necrosis
  • sweating increased
1 - 6 months:
  • back pain
  • depression
  • drug hypersensitivity
  • gastrooesophageal reflux disease
  • insomnia
  • intervertebral disc protrusion
  • thyroid mass
  • anaphylactic reaction
  • anger
  • ankle fracture
6 - 12 months:
  • insomnia
  • dry mouth
  • dry skin
  • urinary hesitation
  • urine abnormality
  • depression
  • migraine hemiplegic
1 - 2 years:
  • gait disturbance
  • rheumatoid arthritis
  • sleep apnoea syndrome
  • anaemia
  • diabetes mellitus
  • disturbance in attention
  • dizziness
  • haemorrhage
  • heart rate increased
  • insomnia
2 - 5 years:
  • mouth dry aggravated
  • adrenal insufficiency
  • alopecia
  • balance disorder
  • chronic fatigue syndrome
  • clonus
  • cough
  • decreased appetite
  • decreased interest
  • depression
5 - 10 years:
  • alopecia
  • anger
  • balance disorder
  • cough
  • decreased appetite
  • decreased interest
  • depression
  • depression aggravated
  • diarrhoea
  • dizziness postural
10+ years:
  • itching
  • mouth dry aggravated
  • chronic fatigue syndrome
  • diarrhoea
  • dry eyes aggravated
  • excessive bronchial secretion
  • fever
  • gastritis
  • headache
  • high blood pressure
not specified:
  • fatigue
  • fall
  • back pain
  • dyspnoea
  • weight decreased
  • headache
  • constipation
  • anaemia
  • arthralgia
  • nausea

Most common drug interactions by gender *:

female:
  • fatigue
  • fall
  • back pain
  • headache
  • weight decreased
  • dyspnoea
  • constipation
  • tenderness
  • anaemia
  • vision blurred
male:
  • nausea
  • anxiety
  • fatigue
  • pain
  • vomiting
  • dyspnoea
  • muscle spasms
  • anaemia
  • asthenia
  • dizziness

Most common drug interactions by age *:

2-9:
  • chest pain
  • drug administration error
  • dyspnoea
  • abdominal pain upper
  • hyperhidrosis
  • initial insomnia
  • neuralgia
  • pain
  • palpitations
  • pneumonitis
10-19:
  • acidosis
  • constipation
  • face oedema
  • insomnia
  • lymphadenopathy
  • nausea
  • viral infection
  • weight decreased
  • hepatic steatosis
  • cardio-respiratory arrest
20-29:
  • blood cholesterol increased
  • deep vein thrombosis
  • diabetes mellitus
  • dizziness
  • extrapyramidal disorder
  • glycosuria
  • hyperglycaemia
  • postural orthostatic tachycardia syndrome
  • tremor
  • type 2 diabetes mellitus
30-39:
  • dehydration
  • depression
  • suicidal ideation
  • fatigue
  • insomnia
  • vomiting
  • constipation
  • diabetes mellitus
  • headache
  • nausea
40-49:
  • pain
  • anxiety
  • atelectasis
  • nausea
  • head injury
  • hypotension
  • insomnia
  • weight increased
  • back pain
  • depression
50-59:
  • fall
  • headache
  • fatigue
  • pain
  • dizziness
  • diarrhoea
  • nausea
  • vision blurred
  • back pain
  • intervertebral disc protrusion
60+:
  • back pain
  • arthralgia
  • tenderness
  • fatigue
  • dyspnoea
  • osteoarthritis
  • anaemia
  • chronic obstructive pulmonary disease
  • deep vein thrombosis
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Ritalin (methylphenidate hydrochloride) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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