Flexeril and Tramadol drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Flexeril and Tramadol together. This review analyzes the effectiveness and drug interactions between Flexeril and Tramadol. It is created by eHealthMe based on reports of 5,110 people who take the same drugs from FDA, and is updated regularly.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,906 users)

Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 77,309 users)

On Feb, 23, 2017

5,110 people who take Flexeril, Tramadol are studied.


Number of reports submitted per year:

Flexeril and Tramadol drug interactions.

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • deep vein thrombosis
  • myocardial infarction
  • pain
  • dizziness
  • myalgia
  • nausea
  • completed suicide
  • pulmonary mass
  • alanine aminotransferase increased
1 - 6 months:
  • pain
  • headache
  • injury
  • anxiety
  • blood pressure increased
  • paraesthesia
  • arthropathy
  • cyanosis
  • drug hypersensitivity
  • emotional distress
6 - 12 months:
  • acute myocardial infarction
  • therapeutic response decreased
  • depression
  • influenza
  • intervertebral disc protrusion
  • intervertebral disc degeneration
  • road traffic accident
  • arthritis
  • back pain
  • renal failure acute
1 - 2 years:
  • pain
  • depression
  • deep vein thrombosis
  • anxiety
  • hallucination
  • abnormal behaviour
  • anaemia
  • desmoid tumour
  • diarrhoea
  • diverticulum
2 - 5 years:
  • depression
  • anxiety
  • suicidal ideation
  • loss of consciousness
  • bipolar disorder
  • aggression
  • convulsion
  • pain
  • feeling abnormal
  • osteoarthritis
5 - 10 years:
  • pain
  • anxiety
  • cyanosis
  • emotional distress
  • gallbladder disorder
  • peripheral ischaemia
  • drug hypersensitivity
  • arterial thrombosis
  • breast cancer female
  • cholecystitis chronic
10+ years:
  • pain
  • abnormal dreams
  • anxiety
  • depression
  • dizziness
  • ear disorder
  • localised infection
  • loss of consciousness
  • suicidal ideation
  • carpal tunnel decompression
not specified:
  • pain
  • nausea
  • fatigue
  • arthralgia
  • headache
  • back pain
  • depression
  • anxiety
  • fall
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • headache
  • arthralgia
  • anxiety
  • back pain
  • depression
  • fall
  • dyspnoea
male:
  • pain
  • depression
  • fall
  • dyspnoea
  • fatigue
  • back pain
  • nausea
  • pain in extremity
  • drug abuse
  • anxiety

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • death
  • abdominal distension
  • abdominal pain upper
  • accidental drug intake by child
  • apnoea
  • asthenia
  • atrial septal defect
  • cardio-respiratory arrest
  • coma
2-9:
  • abdominal pain upper
  • dyspnoea
  • emotional disorder
  • hyperkalaemia
  • pyrexia
  • rash
  • somnolence
  • splenic infarction
  • tardive dyskinesia
  • thrombotic thrombocytopenic purpura
10-19:
  • pain
  • deep vein thrombosis
  • cholecystitis chronic
  • drug ineffective
  • anxiety
  • injury
  • pulmonary embolism
  • nausea
  • gallbladder disorder
  • abdominal pain upper
20-29:
  • pain
  • injury
  • pulmonary embolism
  • deep vein thrombosis
  • anxiety
  • nausea
  • drug abuse
  • fatigue
  • dizziness
  • emotional distress
30-39:
  • pain
  • depression
  • completed suicide
  • drug abuse
  • anxiety
  • headache
  • nausea
  • arthralgia
  • dizziness
  • dyspnoea
40-49:
  • pain
  • depression
  • back pain
  • arthralgia
  • nausea
  • fatigue
  • dyspnoea
  • anxiety
  • headache
  • pain in extremity
50-59:
  • pain
  • headache
  • nausea
  • fatigue
  • arthralgia
  • fall
  • anxiety
  • depression
  • back pain
  • diarrhoea
60+:
  • pain
  • fall
  • dyspnoea
  • back pain
  • pain in extremity
  • fatigue
  • headache
  • arthralgia
  • nausea
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Tramadol?

Interactions between Flexeril and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Tramadol and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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