Flexeril and Zanaflex drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Flexeril and Zanaflex together. This review analyzes the effectiveness and drug interactions between Flexeril and Zanaflex. It is created by eHealthMe based on reports of 914 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Flexeril and Zanaflex, find out what symptoms you could have in 1 year or longer.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 24,906 users)

Zanaflex

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 10,449 users)

On Jan, 31, 2017

914 people who take Flexeril, Zanaflex are studied.


Number of reports submitted per year:

Flexeril and Zanaflex drug interactions.

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • breast cancer
  • dizziness
  • decreased appetite
  • epilepsy
  • fatigue
  • insomnia
  • lung adenocarcinoma
  • memory impairment
  • nausea
1 - 6 months:
  • hyperhidrosis
  • anxiety
  • depression
  • emotional distress
  • fear
  • pain
  • anhedonia
  • dysarthria
  • fall
  • injury
6 - 12 months:
  • arthritis
  • pain
  • anxiety
  • emotional distress
  • gastritis haemorrhagic
  • arthralgia
  • bile duct obstruction
  • coordination abnormal
  • cushingoid
  • dehydration
1 - 2 years:
  • anxiety
  • depression
  • completed suicide
  • deep vein thrombosis
  • emotional distress
  • intentional overdose
  • mental disorder
  • pulmonary embolism
  • suicide attempt
  • ankle fracture
2 - 5 years:
  • somnolence
  • anxiety
  • completed suicide
  • depression
  • dizziness
  • intentional overdose
  • joint swelling
  • mental disorder
  • suicide attempt
  • arthritis
5 - 10 years:
  • emotional distress
  • myocardial infarction
  • pulmonary embolism
  • back disorder
  • blood cholesterol increased
  • anxiety
  • deep vein thrombosis
  • depression
  • pain in extremity
  • dyspnoea
10+ years:
  • decreased appetite
  • surgery
  • weight decreased
  • ill-defined disorder
  • malaise
not specified:
  • pain
  • depression
  • anxiety
  • arthralgia
  • back pain
  • nausea
  • headache
  • dyspnoea
  • asthenia
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • headache
  • anxiety
  • depression
  • arthralgia
  • nausea
  • back pain
  • chest pain
  • asthenia
  • insomnia
male:
  • depression
  • pain
  • anxiety
  • arthralgia
  • emotional distress
  • back pain
  • hypoaesthesia
  • dyspnoea
  • injury
  • nausea

Most common drug interactions by age *:

10-19:
  • anxiety
  • cough
  • nausea
  • pain
  • depression
  • drug dependence
  • drug ineffective
  • drug withdrawal syndrome
  • non-alcoholic steatohepatitis
  • pyrexia
20-29:
  • dizziness
  • pulmonary embolism
  • deep vein thrombosis
  • nausea
  • pain
  • arthralgia
  • depression
  • dyspnoea
  • hypoaesthesia
  • pain in extremity
30-39:
  • arthralgia
  • anxiety
  • pain in extremity
  • depression
  • pain
  • hypertension
  • lymphadenopathy
  • vision blurred
  • drug withdrawal syndrome
  • nausea
40-49:
  • pain
  • depression
  • headache
  • emotional distress
  • chest pain
  • anxiety
  • nausea
  • back pain
  • fall
  • drug dependence
50-59:
  • pain
  • anxiety
  • arthralgia
  • depression
  • back pain
  • dyspnoea
  • headache
  • asthenia
  • muscle spasms
  • osteonecrosis of jaw
60+:
  • pain
  • fall
  • dyspnoea
  • headache
  • deep vein thrombosis
  • osteoarthritis
  • asthenia
  • hyperhidrosis
  • pneumonia
  • muscle spasms

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Zanaflex?

Interactions between Flexeril and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Zanaflex and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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