Review: taking Fluoxetine hydrochloride and Subutex together


Summary

Drug interactions are reported among people who take Fluoxetine hydrochloride and Subutex together. This review analyzes the effectiveness and drug interactions between Fluoxetine hydrochloride and Subutex. It is created by eHealthMe based on reports of 243 people who take the same drugs from FDA and social media, and is updated regularly.

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Fluoxetine Hydrochloride

Fluoxetine hydrochloride has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Fluoxetine hydrochloride 5,577 users)

Subutex

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in drug dependence. (latest outcomes from Subutex 5,007 users)

On Sep, 29, 2016

243 people who take Fluoxetine Hydrochloride, Subutex are studied.


Number of reports submitted per year:

Fluoxetine hydrochloride and Subutex drug interactions.

Drug effectiveness over time:

Fluoxetine Hydrochloride:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 40.0% - (2 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Subutex:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 80.0% - (4 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (3 of 3 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Fluoxetine Hydrochloride:
  • female: 25.0% - (2 of 8 people)
  • male: 22.0% - (2 of 9 people)
Subutex:
  • female: 66.0% - (6 of 9 people)
  • male: 87.0% - (7 of 8 people)

Drug effectiveness by age:

Fluoxetine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 28.0% - (2 of 7 people)
  • 40-49: 50.0% - (2 of 4 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 0 people)
Subutex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 83.0% - (5 of 6 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • mood swings
  • sleepiness
  • headache
  • crying
  • depression
  • drug withdrawal syndrome
  • musculoskeletal pain
  • nausea
  • pain
1 - 6 months:
  • thrombocytopenia
  • foetal exposure during pregnancy
  • bone marrow failure
  • coagulopathy
  • drug withdrawal syndrome neonatal
  • endocarditis staphylococcal
  • hyponatraemia
  • melaena
  • pancytopenia
  • pulmonary embolism
6 - 12 months:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • congenital jaw malformation
  • low birth weight baby
  • premature baby
  • respiratory disorder neonatal
  • abdominal pain
  • abortion induced
  • application site discharge
  • application site discolouration
1 - 2 years:
  • abortion spontaneous
  • hypophagia
  • lethargy
  • malaise
  • cervical vertebral fracture
  • drug effect decreased
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • fall
  • hypoglycaemia
2 - 5 years:
  • abdominal cramps
  • constipation
  • hypophagia
  • lethargy
  • malaise
  • maternal exposure during pregnancy
  • premature labour
  • vomiting
  • adrenal insufficiency
  • appetite - decreased
5 - 10 years:
  • thrombocytopenia
  • acne cystic
10+ years:
  • depression
  • drowsiness
  • dry mouth
  • irritability
  • swallowing difficulty
  • vomiting
  • restlessness
  • hyperacusis
  • myoclonic jerks
  • sweating
not specified:
  • drug withdrawal syndrome neonatal
  • nausea
  • somnolence
  • vomiting
  • foetal exposure during pregnancy
  • pain
  • pneumonia aspiration
  • dyspnoea
  • abdominal pain
  • fall

Most common drug interactions by gender *:

female:
  • somnolence
  • vomiting
  • nausea
  • pneumonia aspiration
  • anxiety
  • pain
  • dry mouth
  • pyrexia
  • depression
  • dyspnoea
male:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • anaemia
  • melaena
  • abdominal pain
  • bone marrow failure
  • coagulopathy
  • endocarditis staphylococcal
  • headache
  • hyponatraemia

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • premature baby
  • anaemia neonatal
  • jaundice neonatal
  • neutropenia neonatal
  • complications of maternal exposure to therapeutic drugs
  • gastro-oesophageal reflux disease
  • hepatomegaly
  • neonatal respiratory distress syndrome
10-19:
  • apgar score low
  • cyanosis neonatal
  • drug withdrawal syndrome neonatal
  • hypotonia neonatal
  • neonatal respiratory depression
  • red man syndrome
20-29:
  • abortion spontaneous
  • abnormal behaviour
  • anxiety
  • depression
  • drug ineffective
  • suicidal ideation
  • abdominal cramps
  • abdominal pain upper
  • accidental overdose
  • acute respiratory distress syndrome
30-39:
  • maternal exposure during pregnancy
  • thrombocytopenia
  • abortion induced
  • bone marrow failure
  • coagulopathy
  • endocarditis staphylococcal
  • hyponatraemia
  • melaena
  • pancytopenia
  • pulmonary embolism
40-49:
  • overdose
  • confusional state
  • accident
  • drug abuse
  • herpes zoster
  • pain
  • pyrexia
  • rash
  • amnesia
  • anaemia
50-59:
  • dry mouth
  • vomiting
  • nausea
  • dyspnoea
  • hypoaesthesia
  • dizziness
  • musculoskeletal pain
  • emotional distress
  • pyrexia
  • abdominal pain
60+:
  • somnolence
  • pneumonia aspiration
  • pain
  • nausea
  • abdominal pain
  • diarrhoea
  • hyperhidrosis
  • vomiting
  • drug ineffective
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fluoxetine hydrochloride (fluoxetine hydrochloride) is often used to treat depression. Subutex (buprenorphine hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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