Review: taking Fluoxetine hydrochloride and Subutex together


Summary

Drug interactions are reported among people who take Fluoxetine hydrochloride and Subutex together. This review analyzes the effectiveness and drug interactions between Fluoxetine hydrochloride and Subutex. It is created by eHealthMe based on reports of 187 people who take the same drugs from FDA and social media, and is updated regularly.

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Fluoxetine Hydrochloride

Fluoxetine hydrochloride has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Fluoxetine hydrochloride 4,802 users)

Subutex

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in drug dependence. (latest outcomes from Subutex 4,079 users)

On Aug, 29, 2016

187 people who take Fluoxetine Hydrochloride, Subutex are studied.


Number of reports submitted per year:

Fluoxetine hydrochloride and Subutex drug interactions.

Drug effectiveness over time:

Fluoxetine Hydrochloride:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 40.0% - (2 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Subutex:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 80.0% - (4 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (3 of 3 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Fluoxetine Hydrochloride:
  • female: 25.0% - (2 of 8 people)
  • male: 22.0% - (2 of 9 people)
Subutex:
  • female: 66.0% - (6 of 9 people)
  • male: 87.0% - (7 of 8 people)

Drug effectiveness by age:

Fluoxetine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 28.0% - (2 of 7 people)
  • 40-49: 50.0% - (2 of 4 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 0 people)
Subutex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 83.0% - (5 of 6 people)
  • 40-49: 75.0% - (3 of 4 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • mood swings
  • sleepiness
  • headache
  • crying
  • musculoskeletal pain
  • abdominal pain
  • affect lability
  • back pain
  • balance disorder
1 - 6 months:
  • thrombocytopenia
  • bone marrow failure
  • coagulopathy
  • endocarditis staphylococcal
  • hyponatraemia
  • melaena
  • pancytopenia
  • pulmonary embolism
  • purpura
  • renal failure
6 - 12 months:
  • foetal exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • low birth weight baby
  • abdominal pain
  • abortion induced
  • application site discharge
  • application site discolouration
  • application site irritation
  • application site pain
  • application site pruritus
1 - 2 years:
  • abortion spontaneous
  • cervical vertebral fracture
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • hypoglycaemia
  • maternal exposure during pregnancy
  • road traffic accident
2 - 5 years:
  • abdominal cramps
  • constipation
  • adrenal insufficiency
  • appetite - decreased
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • hepatic enzyme increased
  • hepatitis
  • jaundice
  • weight loss - unintentional
5 - 10 years:
  • thrombocytopenia
  • acne cystic
10+ years:
  • depression
  • drowsiness
  • dry mouth
  • irritability
  • swallowing difficulty
  • vomiting
  • restlessness
  • hyperacusis
  • myoclonic jerks
  • sweating
not specified:
  • somnolence
  • drug withdrawal syndrome neonatal
  • pneumonia aspiration
  • nausea
  • vomiting
  • anxiety
  • dry mouth
  • dyspnoea
  • foetal exposure during pregnancy
  • accidental overdose

Most common drug interactions by gender *:

female:
  • somnolence
  • pneumonia aspiration
  • nausea
  • anxiety
  • dry mouth
  • vomiting
  • depression
  • dyspnoea
  • musculoskeletal pain
  • pain
male:
  • drug withdrawal syndrome neonatal
  • foetal exposure during pregnancy
  • melaena
  • bone marrow failure
  • coagulopathy
  • endocarditis staphylococcal
  • hyponatraemia
  • pancytopenia
  • pulmonary embolism
  • purpura

Most common drug interactions by age *:

0-1:
  • drug withdrawal syndrome neonatal
  • foetal exposure during pregnancy
  • premature baby
  • anaemia neonatal
  • neutropenia neonatal
  • complications of maternal exposure to therapeutic drugs
  • gastro-oesophageal reflux disease
  • hepatomegaly
  • neonatal respiratory distress syndrome
  • congenital jaw malformation
10-19:
  • apgar score low
  • cyanosis neonatal
  • drug withdrawal syndrome neonatal
  • hypotonia neonatal
  • neonatal respiratory depression
20-29:
  • abortion spontaneous
  • depression
  • abdominal cramps
  • abnormal behaviour
  • accidental overdose
  • acute respiratory distress syndrome
  • agitation
  • anxiety
  • cervical vertebral fracture
  • constipation
30-39:
  • thrombocytopenia
  • maternal exposure during pregnancy
  • abortion induced
  • bone marrow failure
  • coagulopathy
  • endocarditis staphylococcal
  • hyponatraemia
  • melaena
  • pancytopenia
  • pulmonary embolism
40-49:
  • confusional state
  • overdose
  • accident
  • amnesia
  • balance disorder
  • cardiac disorder
  • coronary artery atherosclerosis
  • drug abuser
  • fall
  • gait disturbance
50-59:
  • dry mouth
  • vomiting
  • nausea
  • hypoaesthesia
  • dyspnoea
  • dizziness
  • musculoskeletal pain
  • insomnia
  • abdominal pain
  • accidental overdose
60+:
  • pneumonia aspiration
  • somnolence
  • nausea
  • pain
  • stillbirth
  • abdominal pain
  • accidental overdose
  • acquired oesophageal web
  • ageusia
  • altered state of consciousness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fluoxetine hydrochloride (fluoxetine hydrochloride) is often used to treat depression. Subutex (buprenorphine hydrochloride) is often used to treat drug dependence. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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