Review: taking Fluoxetine and Gabapentin together


Summary

Drug interactions are reported among people who take Fluoxetine and Gabapentin together. This review analyzes the effectiveness and drug interactions between Fluoxetine and Gabapentin. It is created by eHealthMe based on reports of 5,247 people who take the same drugs from FDA and social media, and is updated regularly.

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Fluoxetine

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Fluoxetine 33,136 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 52,972 users)

On Aug, 25, 2016

5,247 people who take Fluoxetine, Gabapentin are studied.


Number of reports submitted per year:

Fluoxetine and Gabapentin drug interactions.

Drug effectiveness over time:

Fluoxetine:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 17.0% - (5 of 29 people)
  • 6 - 12 months: 26.0% - (6 of 23 people)
  • 1 - 2 years: 22.0% - (6 of 27 people)
  • 2 - 5 years: 40.0% - (17 of 42 people)
  • 5 - 10 years: 45.0% - (14 of 31 people)
  • 10+ years: 44.0% - (17 of 38 people)
  • not specified: 100.0% - (2 of 2 people)
Gabapentin:
  • < 1 month: 23.0% - (5 of 21 people)
  • 1 - 6 months: 16.0% - (8 of 48 people)
  • 6 - 12 months: 28.0% - (8 of 28 people)
  • 1 - 2 years: 30.0% - (9 of 30 people)
  • 2 - 5 years: 28.0% - (7 of 25 people)
  • 5 - 10 years: 50.0% - (11 of 22 people)
  • 10+ years: 50.0% - (6 of 12 people)
  • not specified: 50.0% - (2 of 4 people)

Drug effectiveness by gender:

Fluoxetine:
  • female: 37.0% - (59 of 158 people)
  • male: 23.0% - (10 of 42 people)
Gabapentin:
  • female: 31.0% - (47 of 147 people)
  • male: 20.0% - (9 of 43 people)

Drug effectiveness by age:

Fluoxetine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 20.0% - (1 of 5 people)
  • 20-29: 35.0% - (6 of 17 people)
  • 30-39: 24.0% - (12 of 49 people)
  • 40-49: 28.0% - (14 of 49 people)
  • 50-59: 40.0% - (20 of 50 people)
  • 60+: 55.0% - (16 of 29 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 40.0% - (2 of 5 people)
  • 20-29: 46.0% - (7 of 15 people)
  • 30-39: 31.0% - (14 of 44 people)
  • 40-49: 28.0% - (13 of 45 people)
  • 50-59: 21.0% - (11 of 51 people)
  • 60+: 27.0% - (8 of 29 people)

Most common drug interactions over time *:

< 1 month:
  • fatigue
  • nausea
  • atrial fibrillation
  • dizziness
  • drug ineffective
  • feeling abnormal
  • joint swelling
  • abdominal pain
  • cardiac failure congestive
  • dyspnoea
1 - 6 months:
  • depression
  • fatigue
  • headache
  • anxiety
  • tinnitus
  • neck pain
  • constipation
  • arthritis - neck
  • back pain - low
  • blurred vision
6 - 12 months:
  • dizziness
  • fatigue
  • brain neoplasm
  • tinnitus
  • tremor
  • depression
  • memory impairment
  • anxiety
  • ependymoma
  • speech disorder
1 - 2 years:
  • pain
  • anxiety
  • back pain
  • feeling abnormal
  • chronic obstructive pulmonary disease
  • asthenia
  • confusional state
  • foot deformity
  • hallucination
  • sepsis
2 - 5 years:
  • anxiety
  • depression
  • suicide attempt
  • pain
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • weight loss
  • iron deficiency anemia
  • pain inflammation activated
  • drug ineffective
  • bipolar disorder
5 - 10 years:
  • depression
  • headache
  • chronic pain
  • constipation
  • anxiety
  • fatigue
  • migraine
  • arthritis - neck
  • back pain - low
  • blurred vision
10+ years:
  • allodynia
  • constipation
  • suicide attempt
  • dizziness
  • headache
  • nausea
  • alcohol intolerance
  • back injury
  • barrett's oesophagus
  • cardiac failure congestive
not specified:
  • pain
  • depression
  • anxiety
  • nausea
  • fall
  • back pain
  • fatigue
  • dizziness
  • arthralgia
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • depression
  • anxiety
  • fall
  • back pain
  • nausea
  • pain in extremity
  • arthralgia
  • fatigue
  • dizziness
male:
  • anxiety
  • depression
  • pain
  • fatigue
  • nausea
  • headache
  • dizziness
  • constipation
  • asthenia
  • back pain

Most common drug interactions by age *:

0-1:
  • drug exposure during pregnancy
2-9:
  • maternal drugs affecting foetus
  • pain
  • abdominal pain
  • actinic keratosis
  • anaemia
  • appendicitis
  • bone disorder
  • cardiac failure congestive
  • cardiac murmur
  • cardiomyopathy
10-19:
  • gallbladder disorder
  • pain
  • headache
  • tremor
  • cholecystitis chronic
  • pancreatitis
  • sphincter of oddi dysfunction
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
20-29:
  • dizziness
  • dyspnoea
  • headache
  • suicidal ideation
  • asthenia
  • urinary tract infection
  • paranoia
  • chest discomfort
  • back pain
  • cervical dysplasia
30-39:
  • depression
  • anxiety
  • nausea
  • pain
  • type 2 diabetes mellitus
  • pyrexia
  • dizziness
  • diabetes mellitus
  • fatigue
  • completed suicide
40-49:
  • pain
  • depression
  • headache
  • nausea
  • anxiety
  • fatigue
  • diabetes mellitus
  • arthralgia
  • constipation
  • dyspnoea
50-59:
  • pain
  • anxiety
  • depression
  • back pain
  • arthralgia
  • fatigue
  • pain in extremity
  • nausea
  • fall
  • injury
60+:
  • pain
  • fall
  • anxiety
  • back pain
  • dizziness
  • diarrhoea
  • dyspnoea
  • osteonecrosis of jaw
  • pneumonia
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fluoxetine (fluoxetine hydrochloride) is often used to treat depression. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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