Review: taking Fosamax and Cymbalta together


Summary

Drug interactions are reported among people who take Fosamax and Cymbalta together. This review analyzes the effectiveness and drug interactions between Fosamax and Cymbalta. It is created by eHealthMe based on reports of 1,233 people who take the same drugs from FDA and social media, and is updated regularly.

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Fosamax

Fosamax has active ingredients of alendronate sodium. It is often used in osteoporosis. (latest outcomes from Fosamax 81,526 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 89,411 users)

On Sep, 18, 2016

1,233 people who take Fosamax, Cymbalta are studied.


Number of reports submitted per year:

Fosamax and Cymbalta drug interactions.

Drug effectiveness over time:

Fosamax:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Fosamax:
  • female: 0.0% - (0 of 6 people)
  • male: 0.0% - (0 of 1 people)
Cymbalta:
  • female: 33.0% - (3 of 9 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Fosamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 0.0% - (0 of 3 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • fall
  • gastrooesophageal reflux disease
  • nausea
  • arthritis
  • anxiety
  • constipation
  • anaemia
  • bone disorder
  • hypertension
1 - 6 months:
  • palpitations
  • fall
  • gastrooesophageal reflux disease
  • impaired healing
  • nausea
  • osteomyelitis
  • bursitis
  • dental caries
  • headache
  • epistaxis
6 - 12 months:
  • nausea
  • fall
  • vomiting
  • depression
  • arthralgia
  • femur fracture
  • gastrooesophageal reflux disease
  • insomnia
  • arthritis
  • hypertension
1 - 2 years:
  • femur fracture
  • arthralgia
  • pain in extremity
  • fall
  • pain
  • gastrooesophageal reflux disease
  • oedema peripheral
  • bone density decreased
  • arthritis
  • back pain
2 - 5 years:
  • femur fracture
  • arthralgia
  • fall
  • gastrooesophageal reflux disease
  • impaired healing
  • pain
  • depression
  • pain in extremity
  • anxiety
  • low turnover osteopathy
5 - 10 years:
  • femur fracture
  • osteoarthritis
  • low turnover osteopathy
  • fall
  • arthralgia
  • anxiety
  • gastrooesophageal reflux disease
  • constipation
  • depression
  • hypothyroidism
10+ years:
  • femur fracture
  • osteoarthritis
  • low turnover osteopathy
  • osteoporosis
  • colon adenoma
  • cystitis
  • gastrointestinal disorder
  • hypothyroidism
  • lymphoedema
  • menopausal symptoms
not specified:
  • pain
  • fall
  • nausea
  • anxiety
  • depression
  • pain in extremity
  • back pain
  • arthralgia
  • gastrooesophageal reflux disease
  • osteonecrosis of jaw

Most common drug interactions by gender *:

female:
  • pain
  • fall
  • nausea
  • anxiety
  • depression
  • gastrooesophageal reflux disease
  • arthralgia
  • pain in extremity
  • osteonecrosis of jaw
  • back pain
male:
  • nausea
  • fall
  • pain
  • weight decreased
  • depression
  • back pain
  • anxiety
  • dizziness
  • abdominal pain
  • urinary tract infection

Most common drug interactions by age *:

10-19:
  • bone disorder
  • bone pain
  • depression
  • osteoporosis
  • arthropathy
  • cataract
  • convulsion
  • fracture delayed union
  • humerus fracture
  • squamous cell carcinoma
20-29:
  • arthritis
  • bone disorder
  • cataract
  • chronic obstructive pulmonary disease
  • depression
  • diarrhoea
  • osteopenia
  • osteoporosis
  • blood pressure increased
  • convulsion
30-39:
  • nausea
  • vomiting
  • fatigue
  • weight decreased
  • hypothyroidism
  • swelling
  • fall
  • osteonecrosis
  • kidney infection
  • osteomyelitis
40-49:
  • pain
  • nausea
  • anxiety
  • hypertension
  • fall
  • vomiting
  • arthralgia
  • depression
  • constipation
  • diarrhoea
50-59:
  • anxiety
  • pain
  • nausea
  • osteonecrosis of jaw
  • fall
  • tooth disorder
  • impaired healing
  • anhedonia
  • diarrhoea
  • pain in extremity
60+:
  • fall
  • pain
  • arthralgia
  • nausea
  • gastrooesophageal reflux disease
  • depression
  • pain in extremity
  • femur fracture
  • back pain
  • anxiety

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fosamax (alendronate sodium) is often used to treat osteoporosis. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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