Review: taking Gabapentin and Dilantin together


Summary

Drug interactions are reported among people who take Gabapentin and Dilantin together. This review analyzes the effectiveness and drug interactions between Gabapentin and Dilantin. It is created by eHealthMe based on reports of 2,550 people who take the same drugs from FDA and social media, and is updated regularly.

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Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 83,499 users)

Dilantin

Dilantin has active ingredients of phenytoin. It is often used in convulsion. (latest outcomes from Dilantin 4,823 users)

On Sep, 16, 2016

2,550 people who take Gabapentin, Dilantin are studied.


Number of reports submitted per year:

Gabapentin and Dilantin drug interactions.

Drug effectiveness over time:

Gabapentin:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 7 people)
  • 5 - 10 years: 33.0% - (2 of 6 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Dilantin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 0.0% - (0 of 4 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 71.0% - (5 of 7 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Gabapentin:
  • female: 0.0% - (0 of 14 people)
  • male: 22.0% - (2 of 9 people)
Dilantin:
  • female: 53.0% - (8 of 15 people)
  • male: 50.0% - (4 of 8 people)

Drug effectiveness by age:

Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 4 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 9.0% - (1 of 11 people)
  • 60+: 0.0% - (0 of 4 people)
Dilantin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 20.0% - (2 of 10 people)
  • 60+: 100.0% - (5 of 5 people)

Most common drug interactions over time *:

< 1 month:
  • convulsion
  • somnolence
  • asthenia
  • drug hypersensitivity
  • stevens-johnson syndrome
  • fall
  • epilepsy
  • memory impairment
  • pyrexia
  • balance disorder
1 - 6 months:
  • convulsion
  • drug ineffective
  • cardiac tamponade
  • drug hypersensitivity
  • pericardial effusion
  • cardiac arrest
  • fatigue
  • myocardial infarction
  • cerebral arteriovenous malformation haemorrhagic
  • disseminated intravascular coagulation
6 - 12 months:
  • fall
  • memory impairment
  • fatigue
  • weight increased
  • blood triglycerides increased
  • convulsion
  • abdominal distension
  • ankle fracture
  • blood cholesterol increased
  • constipation
1 - 2 years:
  • convulsion
  • confusional state
  • dizziness
  • headache
  • arthralgia
  • coma
  • memory impairment
  • tremor
  • weight increased
  • amnesia
2 - 5 years:
  • drug ineffective
  • convulsion
  • coma
  • headache
  • pain in extremity
  • nervousness
  • speech disorder
  • aplastic anaemia
  • arthralgia
  • balance disorder
5 - 10 years:
  • aplastic anaemia
  • arthralgia
  • coma
  • dry mouth
  • fall
  • muscle spasms
  • pain
  • speech disorder
  • balance disorder
  • convulsion
10+ years:
  • suicide attempt
  • asthenia
  • convulsion
  • depressed level of consciousness
  • drug screen positive
  • drug toxicity
  • fatigue
  • insomnia
  • a-fib
  • adrenal insufficiency
not specified:
  • convulsion
  • drug ineffective
  • pain
  • fatigue
  • fall
  • nausea
  • asthenia
  • depression
  • pain in extremity
  • headache

Most common drug interactions by gender *:

female:
  • convulsion
  • pain
  • drug ineffective
  • nausea
  • asthenia
  • fatigue
  • headache
  • fall
  • depression
  • vomiting
male:
  • convulsion
  • drug ineffective
  • fall
  • fatigue
  • pain
  • tremor
  • asthenia
  • depression
  • grand mal convulsion
  • pain in extremity

Most common drug interactions by age *:

0-1:
  • cleft lip
  • cleft palate
  • congenital megacolon
  • convulsion neonatal
  • drug exposure during pregnancy
  • small for dates baby
2-9:
  • toxic epidermal necrolysis
  • nausea
  • asthenia
  • drug ineffective
  • vomiting
  • appetite decreased
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood bilirubin increased
  • multiple sclerosis
10-19:
  • convulsion
  • anticonvulsant drug level decreased
  • drug ineffective
  • myoclonus
  • insomnia
  • abnormal behaviour
  • agitation
  • drop attacks
  • anticonvulsant drug level below therapeutic
  • complex partial seizures
20-29:
  • fatigue
  • pain
  • cardiac tamponade
  • pericardial effusion
  • cardiac arrest
  • dry skin
  • nephrogenic systemic fibrosis
  • skin tightness
  • pyrexia
  • malaise
30-39:
  • convulsion
  • pain
  • anxiety
  • drug ineffective
  • grand mal convulsion
  • insomnia
  • nausea
  • anaemia
  • asthenia
  • depression
40-49:
  • convulsion
  • drug ineffective
  • pain
  • depression
  • nausea
  • fatigue
  • arthralgia
  • weight increased
  • myocardial infarction
  • anxiety
50-59:
  • convulsion
  • nausea
  • pain
  • asthenia
  • vomiting
  • oedema peripheral
  • pain in extremity
  • anaemia
  • drug ineffective
  • fall
60+:
  • convulsion
  • drug ineffective
  • pain
  • fall
  • confusional state
  • pneumonia
  • asthenia
  • fatigue
  • depression
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Gabapentin (gabapentin) is often used to treat pain. Dilantin (phenytoin) is often used to treat convulsion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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