Review: taking Gabapentin and Dilantin together


Summary

Drug interactions are reported among people who take Gabapentin and Dilantin together. This review analyzes the effectiveness and drug interactions between Gabapentin and Dilantin. It is created by eHealthMe based on reports of 2,022 people who take the same drugs from FDA and social media, and is updated regularly.

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Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 38,775 users)

Dilantin

Dilantin has active ingredients of phenytoin. It is often used in convulsion. (latest outcomes from Dilantin 20,084 users)

On Jul, 19, 2016

2,022 people who take Gabapentin, Dilantin are studied.


Number of reports submitted per year:

Gabapentin and Dilantin drug interactions.

Drug effectiveness over time:

Gabapentin:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 0.0% - (0 of 8 people)
  • 5 - 10 years: 33.0% - (2 of 6 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Dilantin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 0.0% - (0 of 4 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 75.0% - (6 of 8 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Gabapentin:
  • female: 0.0% - (0 of 16 people)
  • male: 20.0% - (2 of 10 people)
Dilantin:
  • female: 52.0% - (9 of 17 people)
  • male: 44.0% - (4 of 9 people)

Drug effectiveness by age:

Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 4 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 7.0% - (1 of 13 people)
  • 60+: 0.0% - (0 of 5 people)
Dilantin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 16.0% - (2 of 12 people)
  • 60+: 100.0% - (6 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • convulsion
  • somnolence
  • asthenia
  • drug hypersensitivity
  • fall
  • epilepsy
  • memory impairment
  • balance disorder
  • pyrexia
  • depression
1 - 6 months:
  • convulsion
  • cardiac tamponade
  • pericardial effusion
  • drug hypersensitivity
  • drug ineffective
  • cardiac arrest
  • fatigue
  • myocardial infarction
  • cerebral arteriovenous malformation haemorrhagic
  • disseminated intravascular coagulation
6 - 12 months:
  • fall
  • memory impairment
  • fatigue
  • weight increased
  • blood triglycerides increased
  • convulsion
  • abdominal distension
  • ankle fracture
  • blood cholesterol increased
  • constipation
1 - 2 years:
  • convulsion
  • confusional state
  • dizziness
  • headache
  • arthralgia
  • coma
  • memory impairment
  • anxiety
  • asthenia
  • diabetes mellitus
2 - 5 years:
  • drug ineffective
  • convulsion
  • coma
  • headache
  • pain in extremity
  • nervousness
  • speech disorder
  • aplastic anaemia
  • arthralgia
  • balance disorder
5 - 10 years:
  • aplastic anaemia
  • arthralgia
  • coma
  • dry mouth
  • fall
  • muscle spasms
  • pain
  • speech disorder
  • balance disorder
  • convulsion
10+ years:
  • suicide attempt
  • convulsion
  • depressed level of consciousness
  • drug screen positive
  • drug toxicity
  • insomnia
  • a-fib
  • adrenal insufficiency
  • amnesia
  • anaemia
not specified:
  • convulsion
  • drug ineffective
  • nausea
  • fatigue
  • pain
  • fall
  • asthenia
  • depression
  • pain in extremity
  • oedema peripheral

Most common drug interactions by gender *:

female:
  • convulsion
  • nausea
  • pain
  • asthenia
  • drug ineffective
  • fatigue
  • fall
  • oedema peripheral
  • depression
  • pain in extremity
male:
  • convulsion
  • drug ineffective
  • fall
  • fatigue
  • pain
  • tremor
  • grand mal convulsion
  • pain in extremity
  • depression
  • asthenia

Most common drug interactions by age *:

0-1:
  • cleft lip
  • cleft palate
  • congenital megacolon
  • convulsion neonatal
  • drug exposure during pregnancy
  • small for dates baby
2-9:
  • nausea
  • asthenia
  • vomiting
  • appetite decreased
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood bilirubin increased
  • multiple sclerosis
  • electroencephalogram abnormal
  • blood alkaline phosphatase increased
10-19:
  • convulsion
  • anticonvulsant drug level decreased
  • myoclonus
  • drug ineffective
  • drop attacks
  • insomnia
  • abnormal behaviour
  • anticonvulsant drug level below therapeutic
  • complex partial seizures
  • drug eruption
20-29:
  • fatigue
  • pain
  • cardiac tamponade
  • pericardial effusion
  • cardiac arrest
  • dry skin
  • nephrogenic systemic fibrosis
  • skin tightness
  • pyrexia
  • multi-organ failure
30-39:
  • convulsion
  • anxiety
  • pain
  • grand mal convulsion
  • renal failure acute
  • insomnia
  • fall
  • depression
  • memory impairment
  • diabetic neuropathy
40-49:
  • convulsion
  • drug ineffective
  • myocardial infarction
  • depression
  • nausea
  • arthralgia
  • fatigue
  • pain
  • weight increased
  • diabetes mellitus
50-59:
  • convulsion
  • nausea
  • asthenia
  • oedema peripheral
  • pain
  • vomiting
  • pain in extremity
  • blood glucose increased
  • arthralgia
  • depression
60+:
  • convulsion
  • fall
  • confusional state
  • drug ineffective
  • pneumonia
  • pain
  • asthenia
  • anxiety
  • depression
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Gabapentin (gabapentin) is often used to treat pain. Dilantin (phenytoin) is often used to treat convulsion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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