Review: taking Gliclazide and Januvia together


Summary

Drug interactions are reported among people who take Gliclazide and Januvia together. This review analyzes the effectiveness and drug interactions between Gliclazide and Januvia. It is created by eHealthMe based on reports of 478 people who take the same drugs from FDA and social media, and is updated regularly.

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Gliclazide

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. (latest outcomes from Gliclazide 5,465 users)

Januvia

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. (latest outcomes from Januvia 25,365 users)

On Aug, 27, 2016

478 people who take Gliclazide, Januvia are studied.


Number of reports submitted per year:

Gliclazide and Januvia drug interactions.

Drug effectiveness over time:

Gliclazide:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Januvia:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Gliclazide:
  • female: 25.0% - (1 of 4 people)
  • male: 0.0% - (0 of 2 people)
Januvia:
  • female: 50.0% - (2 of 4 people)
  • male: 0.0% - (0 of 2 people)

Drug effectiveness by age:

Gliclazide:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 50.0% - (1 of 2 people)
Januvia:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • hypoglycaemia
  • dyspepsia
  • diarrhoea
  • hyperkalaemia
  • renal failure acute
  • anuria
  • oedema peripheral
  • nausea
  • abdominal pain lower
  • enterocolitis haemorrhagic
1 - 6 months:
  • abdominal pain upper
  • rash
  • constipation
  • hyperglycaemia
  • oedema peripheral
  • myalgia
  • arthralgia
  • interstitial lung disease
  • diabetic nephropathy
  • headache
6 - 12 months:
  • cholecystitis acute
  • cholelithiasis
  • diarrhoea
  • diplopia
  • hepatic steatosis
  • liver function test abnormal
  • lymphadenopathy
  • myasthenia gravis
  • nephropathy toxic
  • rash erythematous
1 - 2 years:
  • lower limb fracture
  • diabetic nephropathy
  • metastases to bone
  • pain
  • back pain
  • cerebral haemorrhage
  • drug ineffective
  • fatigue
  • international normalised ratio increased
  • overdose
2 - 5 years:
  • phlebitis
  • visual acuity reduced
  • pancreatic neoplasm
  • pancreatitis chronic
  • pancreatitis acute
  • indigestion
  • swelling of the ankles - feet - legs
  • adenocarcinoma pancreas
  • macular oedema
  • pancreatic disorder
5 - 10 years:
  • nausea
  • vertigo
  • anemia - b12 deficiency
  • hyperglycaemia
not specified:
  • hypoglycaemia
  • metabolic acidosis
  • dyspnoea
  • weight increased
  • headache
  • malaise
  • blood glucose increased
  • vomiting
  • asthenia
  • fatigue

Most common drug interactions by gender *:

female:
  • renal failure acute
  • hyperkalaemia
  • dyspnoea
  • vomiting
  • dyspepsia
  • malaise
  • diarrhoea
  • anuria
  • nausea
  • asthenia
male:
  • hypoglycaemia
  • metabolic acidosis
  • oedema peripheral
  • constipation
  • abdominal pain upper
  • rash
  • headache
  • weight increased
  • fatigue
  • arthralgia

Most common drug interactions by age *:

2-9:
  • acute graft versus host disease
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • bacterial infection
  • blood amylase increased
  • chest pain
  • convulsion
  • haemoglobin decreased
  • myocardial infarction
  • myocardial ischaemia
30-39:
  • abdominal pain
  • blood urine present
  • musculoskeletal pain
  • pain
  • pyelonephritis
  • urinary tract infection
40-49:
  • interstitial lung disease
  • abdominal pain upper
  • angina pectoris
  • arthralgia
  • burning sensation
  • cerebrovascular accident
  • constipation
  • fatigue
  • hypocalcaemia
  • hypoglycaemia
50-59:
  • hypoglycaemia
  • metabolic acidosis
  • weight increased
  • nausea
  • vomiting
  • joint swelling
  • rheumatoid arthritis
  • vomiting projectile
  • dyspnoea
  • lower limb fracture
60+:
  • oedema peripheral
  • diarrhoea
  • dyspnoea
  • hypoglycaemia
  • headache
  • rash
  • dyspepsia
  • renal failure acute
  • hyperkalaemia
  • constipation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Gliclazide (gliclazide) is often used to treat diabetes. Januvia (sitagliptin phosphate) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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