Review: taking Gliclazide and Januvia together


Summary

Drug interactions are reported among people who take Gliclazide and Januvia together. This review analyzes the effectiveness and drug interactions between Gliclazide and Januvia. It is created by eHealthMe based on reports of 748 people who take the same drugs from FDA and social media, and is updated regularly.

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Gliclazide

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. (latest outcomes from Gliclazide 7,942 users)

Januvia

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. (latest outcomes from Januvia 37,219 users)

On Sep, 19, 2016

748 people who take Gliclazide, Januvia are studied.


Number of reports submitted per year:

Gliclazide and Januvia drug interactions.

Drug effectiveness over time:

Gliclazide:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Januvia:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Gliclazide:
  • female: 25.0% - (1 of 4 people)
  • male: 0.0% - (0 of 2 people)
Januvia:
  • female: 50.0% - (2 of 4 people)
  • male: 0.0% - (0 of 2 people)

Drug effectiveness by age:

Gliclazide:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 50.0% - (1 of 2 people)
Januvia:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • hypoglycaemia
  • dyspepsia
  • diarrhoea
  • hyperkalaemia
  • renal failure acute
  • anuria
  • oedema peripheral
  • nausea
  • abdominal pain lower
  • enterocolitis haemorrhagic
1 - 6 months:
  • abdominal pain upper
  • rash
  • constipation
  • myalgia
  • arthralgia
  • hyperglycaemia
  • oedema peripheral
  • fatigue
  • headache
  • interstitial lung disease
6 - 12 months:
  • rash erythematous
  • cholecystitis acute
  • cholelithiasis
  • arthralgia
  • diarrhoea
  • diplopia
  • generalised oedema
  • hepatic steatosis
  • lipase increased
  • liver function test abnormal
1 - 2 years:
  • pancreatitis acute
  • lower limb fracture
  • diabetic nephropathy
  • hypotension
  • metastases to bone
  • pain
  • pancreatic carcinoma
  • suicidal ideation
  • abdominal discomfort
  • abdominal distension
2 - 5 years:
  • pancreatic carcinoma metastatic
  • pancreatic disorder
  • phlebitis
  • visual acuity reduced
  • pancreatitis acute
  • indigestion
  • metastases to liver
  • swelling of the ankles - feet - legs
  • adenocarcinoma pancreas
  • macular oedema
5 - 10 years:
  • nausea
  • vertigo
  • anemia - b12 deficiency
  • hyperglycaemia
not specified:
  • hypoglycaemia
  • diarrhoea
  • malaise
  • fatigue
  • vomiting
  • metabolic acidosis
  • dyspnoea
  • rash
  • pain in extremity
  • hypertension

Most common drug interactions by gender *:

female:
  • diarrhoea
  • drug ineffective
  • vomiting
  • hyperkalaemia
  • hypertension
  • fatigue
  • diabetes mellitus inadequate control
  • hypoglycaemia
  • pain in extremity
  • renal failure acute
male:
  • hypoglycaemia
  • metabolic acidosis
  • rash
  • diarrhoea
  • malaise
  • oedema peripheral
  • vomiting projectile
  • constipation
  • fatigue
  • headache

Most common drug interactions by age *:

2-9:
  • acute graft versus host disease
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • bacterial infection
  • blood amylase increased
  • chest pain
  • convulsion
  • haemoglobin decreased
  • myocardial infarction
  • myocardial ischaemia
30-39:
  • abdominal pain
  • blood urine present
  • musculoskeletal pain
  • pain
  • pyelonephritis
  • urinary tract infection
40-49:
  • rash
  • malaise
  • joint swelling
  • interstitial lung disease
  • abdominal pain upper
  • angina pectoris
  • arthralgia
  • burning sensation
  • cerebrovascular accident
  • constipation
50-59:
  • hypoglycaemia
  • metabolic acidosis
  • vomiting projectile
  • weight increased
  • confusional state
  • fatigue
  • nausea
  • vomiting
  • blood creatinine increased
  • myalgia
60+:
  • diarrhoea
  • hypoglycaemia
  • dyspnoea
  • vomiting
  • oedema peripheral
  • rash
  • hyperkalaemia
  • pain in extremity
  • drug ineffective
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Gliclazide (gliclazide) is often used to treat diabetes. Januvia (sitagliptin phosphate) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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