Review: taking Herceptin and Letrozole together


Summary

Drug interactions are reported among people who take Herceptin and Letrozole together. This review analyzes the effectiveness and drug interactions between Herceptin and Letrozole. It is created by eHealthMe based on reports of 954 people who take the same drugs from FDA and social media, and is updated regularly.

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Herceptin

Herceptin has active ingredients of trastuzumab. It is often used in breast cancer. (latest outcomes from Herceptin 17,937 users)

Letrozole

Letrozole has active ingredients of letrozole. It is often used in breast cancer. (latest outcomes from Letrozole 4,974 users)

On Sep, 29, 2016

954 people who take Herceptin, Letrozole are studied.


Number of reports submitted per year:

Herceptin and Letrozole drug interactions.

Drug effectiveness over time:

Herceptin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Letrozole:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Herceptin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 0 people)
Letrozole:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Herceptin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Letrozole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • rash
  • cough
  • infusion related reaction
  • interstitial lung disease
  • arthralgia
  • back pain
  • decreased appetite
  • disease progression
  • breast cancer
1 - 6 months:
  • disease progression
  • arthralgia
  • pyrexia
  • dyspnoea
  • alopecia
  • cough
  • rash pruritic
  • white blood cell count increased
  • autoimmune thyroiditis
  • blood alkaline phosphatase increased
6 - 12 months:
  • pyrexia
  • chest pain
  • cough
  • disease progression
  • dyspnoea
  • weight decreased
  • fatigue
  • pleural effusion
  • back pain
  • diarrhoea
1 - 2 years:
  • disease progression
  • vomiting
  • decreased appetite
  • fatigue
  • asthenia
  • diarrhoea
  • back pain
  • dyspnoea
  • malignant neoplasm progression
  • osteonecrosis of jaw
2 - 5 years:
  • metastases to bone
  • tooth disorder
  • swelling
  • erythema
  • metastases to lung
  • osteomyelitis
  • pain
  • pain in jaw
  • anaemia
  • blood creatinine increased
5 - 10 years:
  • disease progression
  • neoplasm malignant
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood lactate dehydrogenase increased
  • endocrine neoplasm
  • gamma-glutamyltransferase increased
  • hepatic lesion
  • hepatitis cholestatic
not specified:
  • pain
  • osteonecrosis of jaw
  • anxiety
  • anaemia
  • nausea
  • osteomyelitis
  • fatigue
  • metastases to bone
  • diarrhoea
  • bone disorder

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • anaemia
  • metastases to bone
  • nausea
  • fatigue
  • osteomyelitis
  • diarrhoea
  • bone disorder
male:
  • osteonecrosis of jaw
  • depression
  • osteomyelitis
  • anxiety
  • diarrhoea
  • metastases to bone
  • pathological fracture
  • rib fracture
  • erythema
  • injury

Most common drug interactions by age *:

10-19:
  • alopecia
  • anaemia
  • ataxia
  • cellulitis
  • constipation
  • dysphagia
  • fatigue
  • gait disturbance
  • intervertebral disc degeneration
  • osteomyelitis
20-29:
  • osteonecrosis of jaw
  • anaemia
  • cellulitis
  • depression
  • exposed bone in jaw
  • fatigue
  • lymphoedema
  • metastases to bone
  • metastases to central nervous system
  • nausea
30-39:
  • anaemia
  • osteopenia
  • alopecia
  • biopsy breast abnormal
  • breast cancer female
  • haemorrhoids
  • intervertebral disc protrusion
  • osteoarthritis
  • ovarian cyst
  • acne
40-49:
  • anxiety
  • bone disorder
  • pain
  • anaemia
  • osteonecrosis of jaw
  • tooth extraction
  • injury
  • tooth disorder
  • osteomyelitis
  • nausea
50-59:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • nausea
  • diarrhoea
  • metastases to bone
  • anaemia
  • osteomyelitis
  • dyspnoea
  • arthralgia
60+:
  • pain
  • fatigue
  • diarrhoea
  • metastases to bone
  • pyrexia
  • arthralgia
  • osteonecrosis of jaw
  • disease progression
  • osteonecrosis
  • alopecia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Herceptin (trastuzumab) is often used to treat breast cancer. Letrozole (letrozole) is often used to treat breast cancer. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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