Review: taking Herceptin and Letrozole together


Summary

Drug interactions are reported among people who take Herceptin and Letrozole together. This review analyzes the effectiveness and drug interactions between Herceptin and Letrozole. It is created by eHealthMe based on reports of 721 people who take the same drugs from FDA and social media, and is updated regularly.

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Herceptin

Herceptin has active ingredients of trastuzumab. It is often used in breast cancer. (latest outcomes from Herceptin 13,175 users)

Letrozole

Letrozole has active ingredients of letrozole. It is often used in breast cancer. (latest outcomes from Letrozole 2,337 users)

On Aug, 24, 2016

721 people who take Herceptin, Letrozole are studied.


Number of reports submitted per year:

Herceptin and Letrozole drug interactions.

Drug effectiveness over time:

Herceptin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Letrozole:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Herceptin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 0 people)
Letrozole:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Herceptin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Letrozole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • interstitial lung disease
  • pyrexia
  • cough
  • infusion related reaction
  • viith nerve paralysis
  • blood lactate dehydrogenase increased
  • disease progression
  • dyspnoea at rest
  • erythema
  • haemoglobin decreased
1 - 6 months:
  • disease progression
  • arthralgia
  • pyrexia
  • dyspnoea
  • alopecia
  • cough
  • rash pruritic
  • white blood cell count increased
  • autoimmune thyroiditis
  • blood alkaline phosphatase increased
6 - 12 months:
  • pyrexia
  • chest pain
  • cough
  • disease progression
  • dyspnoea
  • pleural effusion
  • anaemia
  • cardiac arrest
  • diarrhoea
  • fatigue
1 - 2 years:
  • disease progression
  • decreased appetite
  • diarrhoea
  • fatigue
  • asthenia
  • dyspnoea
  • arthropod bite
  • back pain
  • metastases to central nervous system
  • metastases to uterus
2 - 5 years:
  • swelling
  • erythema
  • metastases to lung
  • inflammation
  • metastases to bone
  • osteomyelitis
  • pain
  • pain in jaw
  • pleural effusion
  • anaemia
5 - 10 years:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood lactate dehydrogenase increased
  • disease progression
  • endocrine neoplasm
  • gamma-glutamyltransferase increased
  • hepatic lesion
  • hepatitis cholestatic
  • hypertension aggravated
not specified:
  • pain
  • osteonecrosis of jaw
  • anxiety
  • anaemia
  • osteomyelitis
  • metastases to bone
  • bone disorder
  • pleural effusion
  • nausea
  • primary sequestrum

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • anaemia
  • metastases to bone
  • osteomyelitis
  • bone disorder
  • pleural effusion
  • vomiting
  • pain in jaw
male:
  • osteonecrosis of jaw
  • anxiety
  • metastases to bone
  • depression
  • osteomyelitis
  • pain in jaw
  • diarrhoea
  • pathological fracture
  • rib fracture
  • erythema

Most common drug interactions by age *:

10-19:
  • alopecia
  • anaemia
  • ataxia
  • cellulitis
  • constipation
  • dysphagia
  • fatigue
  • gait disturbance
  • intervertebral disc degeneration
  • osteomyelitis
20-29:
  • metastases to bone
  • metastases to central nervous system
  • abscess jaw
  • alopecia
  • anaemia
  • anxiety
  • bone lesion
  • bone swelling
  • depression
  • dizziness
30-39:
  • anaemia
  • biopsy breast abnormal
  • breast cancer female
  • intervertebral disc protrusion
  • osteopenia
  • ovarian cyst
  • acne
  • alopecia
  • conjunctivitis
  • erythema of eyelid
40-49:
  • anxiety
  • bone disorder
  • anaemia
  • pain
  • osteonecrosis of jaw
  • tooth extraction
  • tooth disorder
  • injury
  • pain in jaw
  • osteomyelitis
50-59:
  • anxiety
  • pain
  • osteonecrosis of jaw
  • anaemia
  • metastases to bone
  • osteomyelitis
  • vomiting
  • diarrhoea
  • fall
  • impaired healing
60+:
  • pain
  • metastases to bone
  • osteonecrosis of jaw
  • diarrhoea
  • fatigue
  • disease progression
  • primary sequestrum
  • erythema
  • osteonecrosis
  • alopecia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Herceptin (trastuzumab) is often used to treat breast cancer. Letrozole (letrozole) is often used to treat breast cancer. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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