Hydrea and Gleevec drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Hydrea and Gleevec together. This review analyzes the effectiveness and drug interactions between Hydrea and Gleevec. It is created by eHealthMe based on reports of 771 people who take the same drugs from FDA, and is updated regularly.

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If you take Hydrea and Gleevec, find out what symptoms you could have in 1 year or longer.

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Hydrea

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. (latest outcomes from Hydrea 4,224 users)

Gleevec

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). (latest outcomes from Gleevec 25,083 users)

On Feb, 20, 2017

771 people who take Hydrea, Gleevec are studied.


Number of reports submitted per year:

Hydrea and Gleevec drug interactions.

Most common drug interactions over time *:

< 1 month:
  • white blood cell count decreased
  • anaemia
  • pyrexia
  • thrombocytopenia
  • platelet count decreased
  • dyspnoea
  • pneumonia
  • blood lactate dehydrogenase increased
  • haemoglobin decreased
  • nausea
1 - 6 months:
  • anaemia
  • haemoglobin decreased
  • fatigue
  • pleural effusion
  • convulsion
  • thrombocytopenia
  • pericardial effusion
  • decreased appetite
  • platelet count increased
  • ascites
6 - 12 months:
  • ascites
  • haemoglobin decreased
  • convulsion
  • electrocardiogram qt prolonged
  • pleurisy
  • atrial fibrillation
  • bradycardia
  • cardiac tamponade
  • gastrointestinal haemorrhage
  • hepatic ischaemia
1 - 2 years:
  • anaemia
  • rash
  • interstitial lung disease
  • ascites
  • haemoglobin decreased
  • oxygen saturation decreased
  • pericardial effusion
  • pleural effusion
  • gastric antral vascular ectasia
  • faeces discoloured
2 - 5 years:
  • neoplasm malignant
  • breast cancer
  • atrial fibrillation
  • pericardial effusion
  • pleural effusion
  • ascites
  • bradycardia
  • cardiac failure
  • cardiac tamponade
  • constipation
5 - 10 years:
  • death
  • gastrointestinal haemorrhage
  • haemorrhoidal haemorrhage
  • leukocytosis
  • major depression
  • neoplasm malignant
  • penis carcinoma
  • renal failure acute
  • cardiac failure
  • breast cancer
10+ years:
  • pancytopenia
  • blast crisis in myelogenous leukaemia
  • confusional state
  • oedema
  • pyrexia
  • renal failure
  • sepsis
  • urine output decreased
not specified:
  • anaemia
  • chronic myeloid leukaemia
  • haemoglobin decreased
  • death
  • nausea
  • pyrexia
  • rash
  • vomiting
  • drug ineffective
  • white blood cell count increased

Most common drug interactions by gender *:

female:
  • anaemia
  • nausea
  • haemoglobin decreased
  • vomiting
  • white blood cell count decreased
  • fatigue
  • pyrexia
  • platelet count decreased
  • chronic myeloid leukaemia
  • platelet count increased
male:
  • haemoglobin decreased
  • chronic myeloid leukaemia
  • pyrexia
  • drug ineffective
  • pleural effusion
  • thrombocytopenia
  • malignant neoplasm progression
  • anaemia
  • blast crisis in myelogenous leukaemia
  • interstitial lung disease

Most common drug interactions by age *:

0-1:
  • premature baby
  • angina pectoris
  • coronary artery occlusion
  • lipase increased
  • developmental hip dysplasia
  • foetal exposure during pregnancy
  • skin hypopigmentation
  • drug exposure during pregnancy
  • drug withdrawal syndrome neonatal
  • normal newborn
2-9:
  • chloroma
  • abasia
  • arthralgia
  • blast crisis in myelogenous leukaemia
  • capillary leak syndrome
  • chromosome analysis abnormal
  • chronic myeloid leukaemia
  • drug ineffective
  • fall
  • febrile neutropenia
10-19:
  • delayed puberty
  • drug exposure during pregnancy
  • loss of consciousness
  • neutropenia
  • death
  • dyspnoea
  • haemothorax
  • leukostasis
  • osteoarthritis
  • placental disorder
20-29:
  • nausea
  • vomiting
  • malaise
  • pleural effusion
  • anaemia
  • blood lactate dehydrogenase increased
  • fatigue
  • haemoglobin decreased
  • weight decreased
  • pancytopenia
30-39:
  • chronic myeloid leukaemia
  • white blood cell count increased
  • vomiting
  • blast crisis in myelogenous leukaemia
  • abdominal pain
  • haemoglobin decreased
  • nausea
  • platelet count increased
  • splenomegaly
  • face oedema
40-49:
  • pyrexia
  • aspartate aminotransferase increased
  • blast crisis in myelogenous leukaemia
  • chronic myeloid leukaemia
  • thrombocytopenia
  • alanine aminotransferase increased
  • blood lactate dehydrogenase increased
  • headache
  • vomiting
  • splenomegaly
50-59:
  • anaemia
  • rash
  • interstitial lung disease
  • neoplasm malignant
  • chronic myeloid leukaemia
  • neutropenia
  • death
  • pyrexia
  • drug ineffective
  • leukopenia
60+:
  • haemoglobin decreased
  • anaemia
  • pleural effusion
  • thrombocytopenia
  • white blood cell count decreased
  • platelet count decreased
  • pyrexia
  • rash
  • decreased appetite
  • pericardial effusion

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Hydrea and Gleevec?

Interactions between Hydrea and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Gleevec and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Hydrea (hydroxyurea) is often used to treat chronic myeloid leukaemia. Gleevec (imatinib mesylate) is often used to treat chronic myeloid leukaemia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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