Review: taking Hydrea and Gleevec together


Summary

Drug interactions are reported among people who take Hydrea and Gleevec together. This review analyzes the effectiveness and drug interactions between Hydrea and Gleevec. It is created by eHealthMe based on reports of 641 people who take the same drugs from FDA and social media, and is updated regularly.

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Hydrea

Hydrea has active ingredients of hydroxyurea. It is often used in chronic myeloid leukaemia. (latest outcomes from Hydrea 3,204 users)

Gleevec

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myeloid leukaemia. (latest outcomes from Gleevec 22,558 users)

On Aug, 27, 2016

641 people who take Hydrea, Gleevec are studied.


Number of reports submitted per year:

Hydrea and Gleevec drug interactions.

Drug effectiveness over time:

Hydrea:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Gleevec:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Hydrea:
  • female: 100.0% - (1 of 1 people)
  • male: 0.0% - (0 of 0 people)
Gleevec:
  • female: 0.0% - (0 of 1 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Hydrea:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 100.0% - (1 of 1 people)
Gleevec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • white blood cell count decreased
  • anaemia
  • pyrexia
  • thrombocytopenia
  • dyspnoea
  • platelet count decreased
  • blood lactate dehydrogenase increased
  • haemoglobin decreased
  • nausea
  • generalised oedema
1 - 6 months:
  • anaemia
  • haemoglobin decreased
  • fatigue
  • convulsion
  • diarrhoea
  • platelet count increased
  • pleural effusion
  • decreased appetite
  • pericardial effusion
  • white blood cell count decreased
6 - 12 months:
  • ascites
  • convulsion
  • pericarditis
  • pleurisy
  • atrial fibrillation
  • bradycardia
  • cardiac failure
  • cardiac tamponade
  • electrocardiogram qt prolonged
  • gastrointestinal haemorrhage
1 - 2 years:
  • anaemia
  • ascites
  • haemoglobin decreased
  • pericardial effusion
  • pleural effusion
  • rash
  • interstitial lung disease
  • oxygen saturation decreased
  • convulsion
  • gastric antral vascular ectasia
2 - 5 years:
  • neoplasm malignant
  • breast cancer
  • atrial fibrillation
  • dyspnoea
  • hepatic function abnormal
  • pericardial effusion
  • pericarditis
  • pleural effusion
  • ascites
  • bradycardia
5 - 10 years:
  • cardiac failure
  • renal failure acute
  • breast cancer
  • death
  • gastrointestinal haemorrhage
  • haemorrhoidal haemorrhage
  • leukocytosis
  • major depression
  • neoplasm malignant
  • penis carcinoma
10+ years:
  • pancytopenia
not specified:
  • haemoglobin decreased
  • anaemia
  • nausea
  • chronic myeloid leukaemia
  • pyrexia
  • vomiting
  • neoplasm malignant
  • white blood cell count increased
  • rash
  • fatigue

Most common drug interactions by gender *:

female:
  • anaemia
  • nausea
  • haemoglobin decreased
  • vomiting
  • fatigue
  • white blood cell count decreased
  • platelet count increased
  • dyspnoea
  • rash
  • pyrexia
male:
  • haemoglobin decreased
  • pyrexia
  • pleural effusion
  • chronic myeloid leukaemia
  • neoplasm malignant
  • interstitial lung disease
  • blast crisis in myelogenous leukaemia
  • white blood cell count increased
  • drug ineffective
  • anaemia

Most common drug interactions by age *:

0-1:
  • angina pectoris
  • coronary artery occlusion
  • lipase increased
  • drug exposure during pregnancy
  • premature baby
  • drug withdrawal syndrome neonatal
  • normal newborn
2-9:
  • chloroma
  • abasia
  • arthralgia
  • blast crisis in myelogenous leukaemia
  • capillary leak syndrome
  • chromosome analysis abnormal
  • chronic myeloid leukaemia
  • drug ineffective
  • fall
  • febrile neutropenia
10-19:
  • drug exposure during pregnancy
  • dyspnoea
  • haemothorax
  • leukostasis
  • placental disorder
  • premature labour
  • respiratory distress
  • viith nerve paralysis
  • white blood cell count increased
  • acute lymphocytic leukaemia
20-29:
  • vomiting
  • nausea
  • malaise
  • blood lactate dehydrogenase increased
  • haemoglobin decreased
  • pleural effusion
  • abdominal discomfort
  • anaemia
  • blood chloride decreased
  • blood creatinine increased
30-39:
  • chronic myeloid leukaemia
  • white blood cell count increased
  • haemoglobin decreased
  • nausea
  • face oedema
  • pyrexia
  • malaise
  • vomiting
  • blast crisis in myelogenous leukaemia
  • abdominal pain
40-49:
  • aspartate aminotransferase increased
  • pyrexia
  • alanine aminotransferase increased
  • blood lactate dehydrogenase increased
  • headache
  • vomiting
  • blast crisis in myelogenous leukaemia
  • thrombocytopenia
  • splenomegaly
  • anaemia haemolytic autoimmune
50-59:
  • rash
  • anaemia
  • interstitial lung disease
  • neoplasm malignant
  • pyrexia
  • chronic myeloid leukaemia
  • drug ineffective
  • gastric antral vascular ectasia
  • oxygen saturation decreased
  • pain in extremity
60+:
  • anaemia
  • haemoglobin decreased
  • pleural effusion
  • white blood cell count decreased
  • pyrexia
  • pericardial effusion
  • decreased appetite
  • platelet count increased
  • neoplasm malignant
  • platelet count decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Hydrea (hydroxyurea) is often used to treat chronic myeloid leukaemia. Gleevec (imatinib mesylate) is often used to treat chronic myeloid leukaemia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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