Hydrocortisone and Melatonin drug interactions - from FDA reports


Drug interactions are reported among people who take Hydrocortisone and Melatonin together. This review analyzes the effectiveness and drug interactions between Hydrocortisone and Melatonin. It is created by eHealthMe based on reports of 113 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Hydrocortisone and Melatonin, find out what symptoms you could have in 1 year or longer.

You are not alone!

Join a support group for people who take Hydrocortisone and Melatonin

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our tools are simple to use, anonymous and free. Start now >>>


Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. (latest outcomes from Hydrocortisone 16,769 users)


Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 9,321 users)

On Feb, 05, 2017

113 people who take Hydrocortisone, Melatonin are studied.

Number of reports submitted per year:

Hydrocortisone and Melatonin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • hyperthermia malignant
  • pericarditis
  • serotonin syndrome
  • body temperature increased
  • hypotension
  • international normalised ratio increased
  • liver function test abnormal
  • renal impairment
  • tachycardia
1 - 6 months:
  • aggression
  • agitation
  • anger
  • belligerence
  • crying
  • disinhibition
  • disturbance in attention
  • disturbance in social behaviour
  • dizziness
  • drug withdrawal syndrome
not specified:
  • pyrexia
  • fatigue
  • pain
  • headache
  • anxiety
  • gingival swelling
  • hot flush
  • impaired healing
  • lymphadenopathy
  • tooth infection

Most common drug interactions by gender *:

  • pyrexia
  • pruritus
  • constipation
  • headache
  • adrenal insufficiency
  • epistaxis
  • fatigue
  • weight increased
  • acne
  • skin odour abnormal
  • fatigue
  • pyrexia
  • dizziness
  • headache
  • abdominal pain upper
  • rash
  • pain
  • cough
  • dysphagia
  • intervertebral disc protrusion

Most common drug interactions by age *:

  • feeling hot
  • flushing
  • infusion related reaction
  • pallor
  • petit mal epilepsy
  • tachypnoea
  • clonus
  • gastroenteritis
  • headache
  • hyponatraemia
  • pyrexia
  • encephalopathy
  • bacteraemia
  • generalised oedema
  • large intestinal ulcer
  • proctitis
  • cardiac arrest
  • fatigue
  • adrenal insufficiency
  • constipation
  • abdominal discomfort
  • abdominal pain upper
  • acute prerenal failure
  • cardiac arrest
  • circulatory collapse
  • coagulopathy
  • compartment syndrome
  • confusional state
  • dizziness
  • enterobacter test positive
  • pericarditis
  • colon cancer
  • hepatic lesion
  • maternal exposure during pregnancy
  • metastases to lymph nodes
  • pruritus generalised
  • fatigue
  • pyrexia
  • weight increased
  • alanine aminotransferase increased
  • analgesic drug level increased
  • arthralgia
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood urea increased
  • blood urea nitrogen/creatinine ratio increased
  • fall
  • contusion
  • incision site erythema
  • incision site infection
  • incision site oedema
  • incision site pain
  • loss of consciousness
  • lower limb fracture
  • pain in extremity
  • tibia fracture
  • fatigue
  • malaise
  • pain
  • abdominal pain upper
  • cough
  • dysphagia
  • injury
  • insomnia
  • scoliosis
  • abscess jaw

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Hydrocortisone and Melatonin?

Interactions between Hydrocortisone and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Melatonin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Hydrocortisone (hydrocortisone) is often used to treat adrenal insufficiency. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

Can you answer these questions?

More questions for: Hydrocortisone, Melatonin

You may be interested in these reviews

More reviews for: Hydrocortisone, Melatonin