Review: taking Hydroxyzine hydrochloride and Ibuprofen together


Summary

Drug interactions are reported among people who take Hydroxyzine hydrochloride and Ibuprofen together. This review analyzes the effectiveness and drug interactions between Hydroxyzine hydrochloride and Ibuprofen. It is created by eHealthMe based on reports of 1,412 people who take the same drugs from FDA and social media, and is updated regularly.

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Hydroxyzine Hydrochloride

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. (latest outcomes from Hydroxyzine hydrochloride 1,397 users)

Ibuprofen

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 70,676 users)

On Aug, 20, 2016

1,412 people who take Hydroxyzine Hydrochloride, Ibuprofen are studied.


Number of reports submitted per year:

Hydroxyzine hydrochloride and Ibuprofen drug interactions.

Drug effectiveness over time:

Hydroxyzine Hydrochloride:
  • < 1 month: 40.0% - (4 of 10 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 60.0% - (3 of 5 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Ibuprofen:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 22.0% - (2 of 9 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Hydroxyzine Hydrochloride:
  • female: 26.0% - (6 of 23 people)
  • male: 66.0% - (4 of 6 people)
Ibuprofen:
  • female: 22.0% - (5 of 22 people)
  • male: 33.0% - (2 of 6 people)

Drug effectiveness by age:

Hydroxyzine Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 44.0% - (4 of 9 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 50.0% - (3 of 6 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 0.0% - (0 of 1 people)
Ibuprofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 25.0% - (1 of 4 people)
  • 20-29: 37.0% - (3 of 8 people)
  • 30-39: 0.0% - (0 of 6 people)
  • 40-49: 20.0% - (1 of 5 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • toxic skin eruption
  • eosinophil count increased
  • suicide attempt
  • anxiety
  • somnolence
  • drug rash with eosinophilia and systemic symptoms
  • fatigue
  • pain
  • overdose
  • sepsis
1 - 6 months:
  • headache
  • bone pain
  • drug rash with eosinophilia and systemic symptoms
  • hip pain
  • leg cramps
  • muscle cramps
  • muscle spasms
  • pain - neck
  • pain in face
  • pain in jaw
6 - 12 months:
  • depression
  • drug ineffective
  • intentional overdose
  • suicidal ideation
  • suicide attempt
  • anxiety aggravated
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • headache
  • hysterectomy
  • irritability
1 - 2 years:
  • myoclonus
  • abdominal distension
  • chest pain
  • constipation
  • cough
  • diarrhoea
  • fainting
  • heart rate irregular
  • hyperlipidaemia
  • lightheadedness - dizzy
2 - 5 years:
  • injury
  • pain
  • pulmonary embolism
  • deep vein thrombosis
  • deformity
  • thrombosis
  • amnesia
  • anger
  • anxiety
  • depression
5 - 10 years:
  • pain
  • deep vein thrombosis
  • injury
  • pulmonary embolism
  • cholecystitis chronic
  • gallbladder disorder
  • headache - tension
  • irritability
  • lack of feeling
  • muscle contractions involuntary
10+ years:
  • emotional distress
  • headache
  • injury
  • pain
  • anxiety
  • bone pain
  • deep vein thrombosis
  • general physical health deterioration
  • hip pain
  • leg cramps
not specified:
  • fatigue
  • depression
  • nausea
  • anxiety
  • dyspnoea
  • pain
  • back pain
  • insomnia
  • weight decreased
  • weight increased

Most common drug interactions by gender *:

female:
  • fatigue
  • depression
  • anxiety
  • dyspnoea
  • back pain
  • nausea
  • pain
  • weight increased
  • insomnia
  • headache
male:
  • nausea
  • vomiting
  • pain
  • fatigue
  • anxiety
  • depression
  • weight decreased
  • dyspnoea
  • arthralgia
  • insomnia

Most common drug interactions by age *:

0-1:
  • anorexia
  • atrial septal defect
  • dehydration
  • fallot's tetralogy
  • irritability
  • lethargy
  • markedly reduced food intake
  • oral candidiasis
  • pulmonary valve stenosis congenital
  • pyrexia
2-9:
  • alanine aminotransferase increased
  • pyrexia
  • aspartate aminotransferase increased
  • toxic epidermal necrolysis
  • transaminases increased
  • abdominal distension
  • blood alkaline phosphatase increased
  • blood chloride decreased
  • blood creatine phosphokinase increased
  • blood potassium increased
10-19:
  • arthritis
  • electrocardiogram qt prolonged
  • pruritus
  • vomiting
  • histiocytosis haematophagic
  • rash erythematous
  • diabetes insipidus
  • electrolyte imbalance
  • acne
  • back pain
20-29:
  • fatigue
  • hodgkin's disease
  • pneumothorax
  • eczema
  • rash
  • ear infection
  • lymphadenopathy
  • vaginal haemorrhage
  • asthenia
  • thrombosis
30-39:
  • pain
  • depression
  • anxiety
  • completed suicide
  • pulmonary embolism
  • dyspnoea
  • headache
  • suicidal ideation
  • diabetes mellitus
  • fatigue
40-49:
  • nausea
  • pain
  • fatigue
  • depression
  • chest pain
  • weight decreased
  • dyspnoea
  • type 2 diabetes mellitus
  • insomnia
  • vomiting
50-59:
  • depression
  • dyspnoea
  • anxiety
  • back pain
  • nausea
  • insomnia
  • fatigue
  • pain
  • urinary tract infection
  • weight decreased
60+:
  • nausea
  • fall
  • pain
  • vomiting
  • gait disturbance
  • fatigue
  • atrial fibrillation
  • anxiety
  • back pain
  • paraesthesia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Hydroxyzine hydrochloride (hydroxyzine hydrochloride) is often used to treat stress and anxiety. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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