Review: taking Imitrex and Benadryl together


Summary

Drug interactions are reported among people who take Imitrex and Benadryl together. This review analyzes the effectiveness and drug interactions between Imitrex and Benadryl. It is created by eHealthMe based on reports of 159 people who take the same drugs from FDA and social media, and is updated regularly.

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Imitrex

Imitrex has active ingredients of sumatriptan. It is often used in migraine. (latest outcomes from Imitrex 1,868 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,260 users)

On Sep, 16, 2016

159 people who take Imitrex, Benadryl are studied.


Number of reports submitted per year:

Imitrex and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  • basal cell carcinoma
  • cerebrovascular accident
  • infusion related reaction
  • lung infection
  • pericarditis
  • abdominal pain upper
  • headache
  • nausea
  • vomiting
  • dyspnoea
1 - 6 months:
  • headache
  • hypotension
  • infusion related reaction
  • intracranial aneurysm
  • pruritus
  • urticaria
not specified:
  • headache
  • nausea
  • vomiting
  • fatigue
  • sinusitis
  • pain
  • diarrhoea
  • migraine
  • hypertension
  • back pain

Most common drug interactions by gender *:

female:
  • headache
  • nausea
  • vomiting
  • sinusitis
  • fatigue
  • pain
  • migraine
  • dyspnoea
  • diarrhoea
  • urticaria
male:
  • anaemia
  • asthenia
  • heart rate increased
  • hypertension
  • pneumonia
  • arthralgia
  • dyspnoea exertional
  • feeling abnormal
  • haematuria
  • herpes zoster

Most common drug interactions by age *:

2-9:
  • contusion
  • musculoskeletal stiffness
  • pain
10-19:
  • palpitations
  • actinic keratosis
  • adenomyosis
  • anaemia
  • anxiety
  • arteriosclerosis coronary artery
  • balance disorder
  • bone density increased
  • bone disorder
  • bronchitis
20-29:
  • nausea
  • vomiting
  • abdominal pain lower
  • breast pain
  • depressed mood
  • depression
  • diarrhoea
  • dizziness
  • drug ineffective
  • drug withdrawal syndrome
30-39:
  • headache
  • nausea
  • urticaria
  • vomiting
  • eye pruritus
  • feeling abnormal
  • pain
  • acne
  • chills
  • dyspnoea
40-49:
  • nausea
  • vomiting
  • headache
  • diarrhoea
  • dyspnoea
  • heart rate increased
  • chest pain
  • cough
  • fatigue
  • hypertension
50-59:
  • headache
  • nausea
  • lung infection
  • vomiting
  • migraine
  • pain in extremity
  • sinusitis
  • anaemia
  • arthralgia
  • back pain
60+:
  • infusion related reaction
  • hypertension
  • headache
  • sinusitis
  • back pain
  • nausea
  • upper respiratory tract infection
  • drug effect decreased
  • catheter site swelling
  • device dislocation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Imitrex (sumatriptan) is often used to treat migraine. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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