Review: taking Imodium and Promethazine together


Summary

Drug interactions are reported among people who take Imodium and Promethazine together. This review analyzes the effectiveness and drug interactions between Imodium and Promethazine. It is created by eHealthMe based on reports of 806 people who take the same drugs from FDA and social media, and is updated regularly.

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Imodium

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. (latest outcomes from Imodium 16,915 users)

Promethazine

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from Promethazine 7,296 users)

On Sep, 18, 2016

806 people who take Imodium, Promethazine are studied.


Number of reports submitted per year:

Imodium and Promethazine drug interactions.

Drug effectiveness over time:

Imodium:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)
Promethazine:
  • < 1 month: 100.0% - (4 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Imodium:
  • female: 60.0% - (3 of 5 people)
  • male: 0.0% - (0 of 1 people)
Promethazine:
  • female: 80.0% - (4 of 5 people)
  • male: 100.0% - (1 of 1 people)

Drug effectiveness by age:

Imodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)
Promethazine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 75.0% - (3 of 4 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • abdominal pain
  • anaemia
  • gastroenteritis
  • nausea
  • graft versus host disease in skin
  • headache
  • multi-organ failure
  • hyperglycaemia
  • renal tubular necrosis
1 - 6 months:
  • stevens-johnson syndrome
  • death
  • diarrhoea
  • myositis
  • rash
  • sinus tachycardia
  • spinal osteoarthritis
  • uterine leiomyoma
  • diabetes mellitus
  • electrocardiogram qt prolonged
6 - 12 months:
  • confusional state
  • pyrexia
1 - 2 years:
  • hypersensitivity
  • pain
  • peripheral swelling
  • psoriatic arthropathy
  • somnolence
2 - 5 years:
  • constipation
  • headache
  • insomnia
  • nausea
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • burning eyes
  • chronic pain
  • chronic pancreatitis
  • chronic sinusitis
  • cognitive deterioration
5 - 10 years:
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • burning eyes
  • chronic pain
  • chronic pancreatitis
  • chronic sinusitis
  • cognitive deterioration
  • constipation
  • depression
  • diarrhea
  • dry mouth
not specified:
  • diarrhoea
  • nausea
  • vomiting
  • dehydration
  • pain
  • abdominal pain
  • fatigue
  • anaemia
  • pneumonia
  • anxiety

Most common drug interactions by gender *:

female:
  • diarrhoea
  • nausea
  • vomiting
  • pain
  • anaemia
  • anxiety
  • dehydration
  • abdominal pain
  • depression
  • urinary tract infection
male:
  • diarrhoea
  • nausea
  • vomiting
  • dehydration
  • fatigue
  • abdominal pain
  • gastrointestinal haemorrhage
  • renal failure acute
  • dizziness
  • pneumonia

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
2-9:
  • foetal exposure during pregnancy
  • premature baby
10-19:
  • blood potassium decreased
  • catheter related infection
  • chills
  • pyrexia
  • anxiety
  • depression
  • hyponatraemia
  • injury
  • vomiting
  • abasia
20-29:
  • anxiety
  • pain
  • cholecystitis chronic
  • injury
  • deep vein thrombosis
  • emotional distress
  • general physical health deterioration
  • gallbladder disorder
  • mental disorder
  • pulmonary embolism
30-39:
  • nausea
  • vomiting
  • headache
  • insomnia
  • fatigue
  • diarrhoea
  • chest pain
  • abdominal pain
  • depression
  • mood swings
40-49:
  • diarrhoea
  • nausea
  • dehydration
  • dyspnoea
  • abdominal pain
  • pain
  • vomiting
  • depression
  • death
  • insomnia
50-59:
  • nausea
  • diarrhoea
  • pneumonia
  • vomiting
  • cardiac failure congestive
  • renal failure acute
  • dehydration
  • anaemia
  • gastrointestinal haemorrhage
  • pain
60+:
  • diarrhoea
  • nausea
  • vomiting
  • anaemia
  • dehydration
  • asthenia
  • fatigue
  • fall
  • pain
  • urinary tract infection

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Imodium (loperamide hydrochloride) is often used to treat diarrhea. Promethazine (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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