Review: taking Klonopin and Effexor xr together


Summary

Drug interactions are reported among people who take Klonopin and Effexor xr together. This review analyzes the effectiveness and drug interactions between Klonopin and Effexor xr. It is created by eHealthMe based on reports of 4,902 people who take the same drugs from FDA and social media, and is updated regularly.

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Klonopin

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 30,926 users)

Effexor Xr

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from Effexor xr 21,661 users)

On Jul, 21, 2016

4,902 people who take Klonopin, Effexor Xr are studied.


Number of reports submitted per year:

Klonopin and Effexor xr drug interactions.

Drug effectiveness over time:

Klonopin:
  • < 1 month: 17.0% - (4 of 23 people)
  • 1 - 6 months: 59.0% - (25 of 42 people)
  • 6 - 12 months: 60.0% - (27 of 45 people)
  • 1 - 2 years: 51.0% - (34 of 66 people)
  • 2 - 5 years: 50.0% - (40 of 79 people)
  • 5 - 10 years: 48.0% - (27 of 56 people)
  • 10+ years: 60.0% - (27 of 45 people)
  • not specified: 50.0% - (2 of 4 people)
Effexor Xr:
  • < 1 month: 11.0% - (2 of 17 people)
  • 1 - 6 months: 23.0% - (10 of 42 people)
  • 6 - 12 months: 19.0% - (8 of 41 people)
  • 1 - 2 years: 38.0% - (19 of 49 people)
  • 2 - 5 years: 42.0% - (31 of 73 people)
  • 5 - 10 years: 35.0% - (31 of 87 people)
  • 10+ years: 48.0% - (24 of 49 people)
  • not specified: 0.0% - (0 of 5 people)

Drug effectiveness by gender:

Klonopin:
  • female: 55.0% - (140 of 254 people)
  • male: 43.0% - (46 of 106 people)
Effexor Xr:
  • female: 33.0% - (86 of 258 people)
  • male: 37.0% - (39 of 105 people)

Drug effectiveness by age:

Klonopin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 71.0% - (5 of 7 people)
  • 20-29: 42.0% - (18 of 42 people)
  • 30-39: 52.0% - (39 of 74 people)
  • 40-49: 62.0% - (64 of 103 people)
  • 50-59: 52.0% - (42 of 80 people)
  • 60+: 33.0% - (18 of 54 people)
Effexor Xr:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 22.0% - (2 of 9 people)
  • 20-29: 23.0% - (9 of 38 people)
  • 30-39: 30.0% - (22 of 71 people)
  • 40-49: 40.0% - (44 of 109 people)
  • 50-59: 35.0% - (28 of 78 people)
  • 60+: 34.0% - (20 of 58 people)

Most common drug interactions over time *:

< 1 month:
  • drug withdrawal syndrome
  • nausea
  • headache
  • suicidal ideation
  • anxiety
  • completed suicide
  • drug ineffective
  • dizziness
  • depression
  • feeling abnormal
1 - 6 months:
  • pain
  • anxiety
  • suicidal ideation
  • nausea
  • convulsion
  • drug ineffective
  • weight decreased
  • depression
  • drug withdrawal syndrome
  • suicide attempt
6 - 12 months:
  • nausea
  • drug withdrawal syndrome
  • anxiety
  • fatigue
  • headache
  • dizziness
  • vision blurred
  • irritability
  • alopecia
  • influenza like illness
1 - 2 years:
  • emotional distress
  • drug ineffective
  • pain
  • depression
  • constipation
  • insomnia
  • cerebrovascular accident
  • headache
  • rash
  • cardiomyopathy
2 - 5 years:
  • depression
  • type 2 diabetes mellitus
  • abdominal pain
  • vomiting
  • impaired healing
  • diarrhoea
  • suicidal ideation
  • insomnia
  • osteomyelitis
  • sepsis
5 - 10 years:
  • depression
  • anxiety
  • insomnia
  • fatigue
  • diabetes mellitus
  • pancreatitis
  • weight increased
  • drug withdrawal syndrome
  • pulmonary embolism
  • arthritis
10+ years:
  • fatigue
  • drug ineffective
  • depression aggravated
  • anxiety
  • coronary artery disease
  • dry mouth
  • movement disorder
  • multiple sclerosis
  • tardive dyskinesia
  • type 2 diabetes mellitus
not specified:
  • depression
  • anxiety
  • nausea
  • pain
  • diabetes mellitus
  • headache
  • fatigue
  • weight increased
  • insomnia
  • suicidal ideation

Most common drug interactions by gender *:

female:
  • depression
  • nausea
  • anxiety
  • pain
  • headache
  • fatigue
  • insomnia
  • diabetes mellitus
  • suicidal ideation
  • weight increased
male:
  • diabetes mellitus
  • anxiety
  • depression
  • pain
  • type 2 diabetes mellitus
  • suicidal ideation
  • drug ineffective
  • weight increased
  • back pain
  • fatigue

Most common drug interactions by age *:

0-1:
  • premature baby
  • anorexia
  • anxiety
  • asthma
  • bronchitis
  • congenital bladder anomaly
  • deep vein thrombosis
  • diabetes mellitus
  • drug exposure during pregnancy
  • drug exposure via breast milk
2-9:
  • neck tightness
  • palpitations
  • photophobia
  • pyrexia
  • serotonin syndrome
10-19:
  • suicidal ideation
  • weight increased
  • anger
  • depression
  • aggression
  • agitation
  • completed suicide
  • pain
  • diabetes mellitus
  • drug ineffective
20-29:
  • suicide attempt
  • anxiety
  • depression
  • nausea
  • suicidal ideation
  • type 2 diabetes mellitus
  • fatigue
  • muscle spasms
  • diabetes mellitus
  • pain
30-39:
  • diabetes mellitus
  • nausea
  • depression
  • anxiety
  • type 2 diabetes mellitus
  • suicidal ideation
  • suicide attempt
  • weight increased
  • dizziness
  • headache
40-49:
  • nausea
  • diabetes mellitus
  • headache
  • pain
  • depression
  • type 2 diabetes mellitus
  • fatigue
  • anxiety
  • weight increased
  • oedema peripheral
50-59:
  • depression
  • pain
  • anxiety
  • insomnia
  • headache
  • nausea
  • diarrhoea
  • dizziness
  • fatigue
  • diabetes mellitus
60+:
  • depression
  • anxiety
  • pain
  • fall
  • drug ineffective
  • nausea
  • fatigue
  • headache
  • dizziness
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Effexor xr (venlafaxine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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