Review: taking Klonopin and Effexor xr together


Summary

Drug interactions are reported among people who take Klonopin and Effexor xr together. This review analyzes the effectiveness and drug interactions between Klonopin and Effexor xr. It is created by eHealthMe based on reports of 6,839 people who take the same drugs from FDA and social media, and is updated regularly.

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Klonopin

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 41,671 users)

Effexor Xr

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from Effexor xr 27,070 users)

On Sep, 16, 2016

6,839 people who take Klonopin, Effexor Xr are studied.


Number of reports submitted per year:

Klonopin and Effexor xr drug interactions.

Drug effectiveness over time:

Klonopin:
  • < 1 month: 18.0% - (4 of 22 people)
  • 1 - 6 months: 52.0% - (19 of 36 people)
  • 6 - 12 months: 52.0% - (18 of 34 people)
  • 1 - 2 years: 39.0% - (18 of 46 people)
  • 2 - 5 years: 53.0% - (36 of 67 people)
  • 5 - 10 years: 50.0% - (24 of 48 people)
  • 10+ years: 61.0% - (21 of 34 people)
  • not specified: 33.0% - (1 of 3 people)
Effexor Xr:
  • < 1 month: 11.0% - (2 of 17 people)
  • 1 - 6 months: 24.0% - (9 of 37 people)
  • 6 - 12 months: 25.0% - (8 of 32 people)
  • 1 - 2 years: 26.0% - (10 of 38 people)
  • 2 - 5 years: 51.0% - (29 of 56 people)
  • 5 - 10 years: 35.0% - (24 of 67 people)
  • 10+ years: 50.0% - (18 of 36 people)
  • not specified: 0.0% - (0 of 4 people)

Drug effectiveness by gender:

Klonopin:
  • female: 49.0% - (101 of 203 people)
  • male: 45.0% - (40 of 87 people)
Effexor Xr:
  • female: 34.0% - (69 of 200 people)
  • male: 35.0% - (31 of 87 people)

Drug effectiveness by age:

Klonopin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 71.0% - (5 of 7 people)
  • 20-29: 39.0% - (13 of 33 people)
  • 30-39: 50.0% - (33 of 66 people)
  • 40-49: 59.0% - (49 of 82 people)
  • 50-59: 45.0% - (27 of 59 people)
  • 60+: 32.0% - (14 of 43 people)
Effexor Xr:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 22.0% - (2 of 9 people)
  • 20-29: 25.0% - (8 of 31 people)
  • 30-39: 32.0% - (20 of 62 people)
  • 40-49: 42.0% - (36 of 84 people)
  • 50-59: 29.0% - (17 of 58 people)
  • 60+: 39.0% - (17 of 43 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • drug withdrawal syndrome
  • headache
  • drug ineffective
  • anxiety
  • suicidal ideation
  • feeling abnormal
  • depression
  • dizziness
  • insomnia
1 - 6 months:
  • anxiety
  • drug ineffective
  • pain
  • nausea
  • suicidal ideation
  • depression
  • convulsion
  • drug withdrawal syndrome
  • weight decreased
  • dizziness
6 - 12 months:
  • drug withdrawal syndrome
  • nausea
  • anxiety
  • headache
  • fatigue
  • pain
  • dizziness
  • vision blurred
  • depression
  • irritability
1 - 2 years:
  • pain
  • emotional distress
  • drug ineffective
  • depression
  • constipation
  • headache
  • insomnia
  • rash
  • cardiomyopathy
  • cerebrovascular accident
2 - 5 years:
  • depression
  • abdominal pain
  • type 2 diabetes mellitus
  • vomiting
  • impaired healing
  • insomnia
  • suicidal ideation
  • diarrhoea
  • pain
  • suicide attempt
5 - 10 years:
  • anxiety
  • depression
  • insomnia
  • drug withdrawal syndrome
  • fatigue
  • diabetes mellitus
  • pancreatitis
  • paraesthesia
  • weight increased
  • withdrawal syndrome
10+ years:
  • fatigue
  • drug ineffective
  • anxiety
  • movement disorder
  • back injury
  • depression aggravated
  • drug withdrawal syndrome
  • insomnia
  • accident at work
  • coronary artery disease
not specified:
  • depression
  • anxiety
  • nausea
  • pain
  • headache
  • drug ineffective
  • fatigue
  • insomnia
  • dizziness
  • weight increased

Most common drug interactions by gender *:

female:
  • depression
  • nausea
  • anxiety
  • headache
  • pain
  • fatigue
  • drug ineffective
  • insomnia
  • diarrhoea
  • dizziness
male:
  • anxiety
  • drug ineffective
  • depression
  • pain
  • diabetes mellitus
  • fall
  • dizziness
  • back pain
  • fatigue
  • insomnia

Most common drug interactions by age *:

0-1:
  • premature baby
  • anorexia
  • anxiety
  • asthma
  • atrial septal defect
  • bronchitis
  • cardiac murmur
  • congenital bladder anomaly
  • deep vein thrombosis
  • dermal cyst
2-9:
  • cardiovascular disorder
  • electrolyte imbalance
  • intentional overdose
  • mental disorder
  • suicide attempt
  • balance disorder
  • hypertension
  • photophobia
  • pyrexia
  • international normalised ratio increased
10-19:
  • suicidal ideation
  • hyperhidrosis
  • hepatic enzyme increased
  • depression
  • autoimmune hepatitis
  • insomnia
  • malaise
  • weight increased
  • anger
  • drug ineffective
20-29:
  • anxiety
  • nausea
  • drug ineffective
  • depression
  • suicide attempt
  • fatigue
  • suicidal ideation
  • vomiting
  • dyspnoea
  • pain
30-39:
  • nausea
  • depression
  • anxiety
  • diabetes mellitus
  • suicidal ideation
  • type 2 diabetes mellitus
  • headache
  • dizziness
  • weight increased
  • fatigue
40-49:
  • nausea
  • headache
  • pain
  • depression
  • fatigue
  • anxiety
  • diabetes mellitus
  • weight increased
  • type 2 diabetes mellitus
  • drug ineffective
50-59:
  • depression
  • pain
  • anxiety
  • insomnia
  • headache
  • nausea
  • drug ineffective
  • diarrhoea
  • fatigue
  • dizziness
60+:
  • drug ineffective
  • depression
  • anxiety
  • pain
  • nausea
  • fall
  • headache
  • fatigue
  • malaise
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Effexor xr (venlafaxine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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