Review: taking Klonopin and Melatonin together


Summary

Drug interactions are reported among people who take Klonopin and Melatonin together. This review analyzes the effectiveness and drug interactions between Klonopin and Melatonin. It is created by eHealthMe based on reports of 716 people who take the same drugs from FDA and social media, and is updated regularly.

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Klonopin

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 41,671 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 8,403 users)

On Sep, 17, 2016

716 people who take Klonopin, Melatonin are studied.


Number of reports submitted per year:

Klonopin and Melatonin drug interactions.

Drug effectiveness over time:

Klonopin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 25.0% - (2 of 8 people)
  • 6 - 12 months: 75.0% - (3 of 4 people)
  • 1 - 2 years: 83.0% - (5 of 6 people)
  • 2 - 5 years: 25.0% - (2 of 8 people)
  • 5 - 10 years: 70.0% - (7 of 10 people)
  • 10+ years: 83.0% - (5 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 66.0% - (4 of 6 people)
  • 1 - 2 years: 25.0% - (3 of 12 people)
  • 2 - 5 years: 45.0% - (5 of 11 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Klonopin:
  • female: 56.0% - (18 of 32 people)
  • male: 63.0% - (7 of 11 people)
Melatonin:
  • female: 31.0% - (10 of 32 people)
  • male: 66.0% - (6 of 9 people)

Drug effectiveness by age:

Klonopin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 14.0% - (1 of 7 people)
  • 30-39: 60.0% - (3 of 5 people)
  • 40-49: 22.0% - (2 of 9 people)
  • 50-59: 90.0% - (9 of 10 people)
  • 60+: 88.0% - (8 of 9 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 28.0% - (2 of 7 people)
  • 30-39: 20.0% - (1 of 5 people)
  • 40-49: 33.0% - (3 of 9 people)
  • 50-59: 60.0% - (6 of 10 people)
  • 60+: 28.0% - (2 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • depressed level of consciousness
  • accidental exposure
  • confusional state
  • incontinence
  • lethargy
  • general physical health deterioration
  • pain
  • unresponsive to stimuli
  • abdominal adhesions
  • bronchopneumonia
1 - 6 months:
  • arthritis
  • pseudoporphyria
  • anxiety
  • depression
  • anxiety disorder
  • constipation
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
6 - 12 months:
  • fatigue
  • hypertension
  • depression
  • frequent or urgent urination
  • hyperlipidemia
  • insomnia
  • restless leg syndrome
  • seroma
  • tachycardia
  • type 2 diabetes
1 - 2 years:
  • insomnia
  • constipation aggravated
  • heat intolerance
  • dark circles under eyes
  • hypertension
  • insomnia related to another mental condition
  • movement - uncoordinated
  • nightmares - repeated
  • restless leg syndrome
  • supraventricular tachycardia
2 - 5 years:
  • arthritis
  • pseudoporphyria
  • anxiety
  • constipation
  • depression
  • anxiety disorder
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
5 - 10 years:
  • inflammation localised
  • arthritis
  • fear of weight gain
  • hearing loss
  • altered state of consciousness
  • anxiety
  • atypical pneumonia
  • bone and joint pain
  • botulism
  • breath sounds abnormal
10+ years:
  • dark circles under eyes
  • insomnia related to another mental condition
  • movement - uncoordinated
  • nightmares - repeated
  • supraventricular tachycardia
  • teeth grinding and clenching
  • vision blurred
  • diarrhoea
  • skin blushing/flushing
  • aortic valve stenosis
not specified:
  • fatigue
  • nausea
  • insomnia
  • pain
  • drug ineffective
  • pneumonia
  • fall
  • depression
  • dizziness
  • anxiety

Most common drug interactions by gender *:

female:
  • fatigue
  • nausea
  • pain
  • insomnia
  • depression
  • drug ineffective
  • anxiety
  • pneumonia
  • fall
  • diarrhoea
male:
  • fatigue
  • insomnia
  • drug ineffective
  • anxiety
  • somnolence
  • dizziness
  • feeling abnormal
  • diarrhoea
  • arthralgia
  • fall

Most common drug interactions by age *:

0-1:
  • blood alkaline phosphatase increased
  • cough
  • feeling cold
  • gamma-glutamyltransferase increased
  • gastroenteritis
  • pneumonia
  • pyrexia
  • respiratory syncytial virus infection
  • respiratory tract congestion
  • somnolence
2-9:
  • anger
  • sudden death
  • syncope
  • convulsion
  • dehydration
  • insomnia
  • joint dislocation
  • lethargy
  • anxiety
  • application site erythema
10-19:
  • convulsion
  • pyrexia
  • anticonvulsant drug level decreased
  • agitation
  • decreased appetite
  • cerebrospinal fluid leakage
  • decubitus ulcer
  • hydrocephalus
  • implant site infection
  • lethargy
20-29:
  • seizure
  • hyponatraemia
  • restlessness
  • dizziness
  • anxiety
  • malaise
  • palpitations
  • abdominal discomfort
  • dyspnoea
  • hypoaesthesia
30-39:
  • pain
  • flushing
  • lip disorder
  • fatigue
  • insomnia
  • seizure
  • oedema peripheral
  • pain in extremity
  • abdominal pain upper
  • anxiety
40-49:
  • bronchitis
  • fatigue
  • depression
  • nausea
  • cystitis
  • cystitis haemorrhagic
  • hip arthroplasty
  • pneumonia
  • pneumonia aspiration
  • urinary bladder haemorrhage
50-59:
  • insomnia
  • pain
  • confusional state
  • fall
  • depression
  • anxiety
  • drug ineffective
  • fatigue
  • diarrhoea
  • gait disturbance
60+:
  • drug ineffective
  • fatigue
  • insomnia
  • fall
  • influenza like illness
  • pneumonia
  • nausea
  • arthralgia
  • diarrhoea
  • visual impairment

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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