Review: taking Klonopin and Wellbutrin together


Summary

Drug interactions are reported among people who take Klonopin and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Klonopin and Wellbutrin. It is created by eHealthMe based on reports of 5,691 people who take the same drugs from FDA and social media, and is updated regularly.

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Klonopin

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 30,926 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 54,663 users)

On Jul, 22, 2016

5,691 people who take Klonopin, Wellbutrin are studied.


Number of reports submitted per year:

Klonopin and Wellbutrin drug interactions.

Drug effectiveness over time:

Klonopin:
  • < 1 month: 34.0% - (16 of 47 people)
  • 1 - 6 months: 48.0% - (49 of 102 people)
  • 6 - 12 months: 48.0% - (37 of 77 people)
  • 1 - 2 years: 54.0% - (52 of 96 people)
  • 2 - 5 years: 70.0% - (194 of 277 people)
  • 5 - 10 years: 65.0% - (70 of 107 people)
  • 10+ years: 75.0% - (71 of 94 people)
  • not specified: 63.0% - (7 of 11 people)
Wellbutrin:
  • < 1 month: 15.0% - (9 of 59 people)
  • 1 - 6 months: 22.0% - (24 of 108 people)
  • 6 - 12 months: 27.0% - (25 of 92 people)
  • 1 - 2 years: 31.0% - (30 of 94 people)
  • 2 - 5 years: 20.0% - (49 of 239 people)
  • 5 - 10 years: 58.0% - (72 of 123 people)
  • 10+ years: 48.0% - (33 of 68 people)
  • not specified: 50.0% - (4 of 8 people)

Drug effectiveness by gender:

Klonopin:
  • female: 63.0% - (381 of 602 people)
  • male: 55.0% - (115 of 209 people)
Wellbutrin:
  • female: 28.0% - (169 of 586 people)
  • male: 37.0% - (77 of 205 people)

Drug effectiveness by age:

Klonopin:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 20.0% - (1 of 5 people)
  • 20-29: 74.0% - (131 of 175 people)
  • 30-39: 60.0% - (109 of 180 people)
  • 40-49: 58.0% - (105 of 180 people)
  • 50-59: 52.0% - (95 of 182 people)
  • 60+: 61.0% - (54 of 88 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 57.0% - (4 of 7 people)
  • 20-29: 13.0% - (24 of 174 people)
  • 30-39: 31.0% - (54 of 171 people)
  • 40-49: 34.0% - (61 of 175 people)
  • 50-59: 42.0% - (74 of 176 people)
  • 60+: 33.0% - (29 of 87 people)

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • depression
  • dizziness
  • drug ineffective
  • insomnia
  • nausea
  • convulsion
  • fall
  • pain
  • suicidal ideation
1 - 6 months:
  • drug exposure during pregnancy
  • cardiomegaly
  • congenital anomaly
  • dilatation ventricular
  • truncus arteriosus persistent
  • ventricular septal defect
  • bundle branch block right
  • aortic stenosis
  • depression
  • cardiac murmur
6 - 12 months:
  • nausea
  • depression
  • type 2 diabetes mellitus
  • back pain
  • anxiety
  • headache
  • fatigue
  • anxiety disorder
  • muscle spasms
  • abdominal discomfort
1 - 2 years:
  • anxiety
  • type 2 diabetes mellitus
  • gastric ulcer
  • nausea
  • cardiac arrest
  • depression
  • headache
  • myocardial infarction
  • cardiac failure congestive
  • fatigue
2 - 5 years:
  • hair loss
  • depression
  • fatigue
  • nausea
  • anxiety
  • headache
  • type 2 diabetes mellitus
  • diabetes mellitus
  • anxiety disorder
  • constipation
5 - 10 years:
  • depression
  • anxiety
  • nausea
  • dizziness
  • irritability
  • intentional overdose
  • suicide attempt
  • vision blurred
  • anger
  • weight gain
10+ years:
  • pain
  • depression
  • fatigue
  • dry mouth
  • angioedema
  • anxiety
  • chest pain
  • swollen tongue
  • constipation
  • pancreatitis
not specified:
  • depression
  • anxiety
  • nausea
  • weight increased
  • drug ineffective
  • pain
  • diabetes mellitus
  • fatigue
  • insomnia
  • dizziness

Most common drug interactions by gender *:

female:
  • depression
  • anxiety
  • nausea
  • pain
  • weight increased
  • drug ineffective
  • insomnia
  • fatigue
  • headache
  • dizziness
male:
  • depression
  • diabetes mellitus
  • type 2 diabetes mellitus
  • drug ineffective
  • weight increased
  • anxiety
  • fatigue
  • suicidal ideation
  • insomnia
  • fall

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • anhedonia
  • anxiety
  • deep vein thrombosis
  • dysphagia
  • fear
  • food craving
  • hyperglycaemia
2-9:
  • dysphagia
  • laryngomalacia
  • speech disorder
  • drug exposure during pregnancy
  • dizziness
  • headache
  • maternal drugs affecting foetus
  • weight decreased
10-19:
  • nausea
  • somnolence
  • vomiting
  • back pain
  • cholecystitis chronic
  • abdominal discomfort
  • abdominal pain upper
  • biliary dyskinesia
  • cholecystitis
  • gallbladder cholesterolosis
20-29:
  • hair loss
  • completed suicide
  • depression
  • drug ineffective
  • suicidal ideation
  • weight increased
  • grand mal convulsion
  • suicide attempt
  • convulsion
  • diabetes mellitus
30-39:
  • diabetes mellitus
  • nausea
  • type 2 diabetes mellitus
  • anxiety
  • weight increased
  • depression
  • pain
  • completed suicide
  • insomnia
  • suicidal ideation
40-49:
  • depression
  • nausea
  • anxiety
  • diabetes mellitus
  • fatigue
  • pain
  • dizziness
  • type 2 diabetes mellitus
  • weight increased
  • suicidal ideation
50-59:
  • depression
  • anxiety
  • fall
  • pain
  • nausea
  • weight increased
  • fatigue
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
60+:
  • drug ineffective
  • fatigue
  • nausea
  • dizziness
  • depression
  • headache
  • asthenia
  • weight increased
  • anxiety
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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