Review: taking Klonopin and Wellbutrin together


Summary

Drug interactions are reported among people who take Klonopin and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Klonopin and Wellbutrin. It is created by eHealthMe based on reports of 6,571 people who take the same drugs from FDA and social media, and is updated regularly.

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Klonopin

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 34,034 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 58,718 users)

On Aug, 20, 2016

6,571 people who take Klonopin, Wellbutrin are studied.


Number of reports submitted per year:

Klonopin and Wellbutrin drug interactions.

Drug effectiveness over time:

Klonopin:
  • < 1 month: 35.0% - (16 of 45 people)
  • 1 - 6 months: 47.0% - (44 of 93 people)
  • 6 - 12 months: 46.0% - (29 of 62 people)
  • 1 - 2 years: 54.0% - (44 of 81 people)
  • 2 - 5 years: 54.0% - (76 of 139 people)
  • 5 - 10 years: 67.0% - (57 of 84 people)
  • 10+ years: 73.0% - (53 of 72 people)
  • not specified: 62.0% - (5 of 8 people)
Wellbutrin:
  • < 1 month: 16.0% - (9 of 53 people)
  • 1 - 6 months: 21.0% - (19 of 89 people)
  • 6 - 12 months: 30.0% - (22 of 73 people)
  • 1 - 2 years: 32.0% - (25 of 77 people)
  • 2 - 5 years: 33.0% - (40 of 118 people)
  • 5 - 10 years: 53.0% - (50 of 94 people)
  • 10+ years: 50.0% - (27 of 54 people)
  • not specified: 40.0% - (2 of 5 people)

Drug effectiveness by gender:

Klonopin:
  • female: 56.0% - (230 of 407 people)
  • male: 53.0% - (95 of 178 people)
Wellbutrin:
  • female: 34.0% - (133 of 390 people)
  • male: 35.0% - (62 of 174 people)

Drug effectiveness by age:

Klonopin:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 20.0% - (1 of 5 people)
  • 20-29: 51.0% - (41 of 80 people)
  • 30-39: 60.0% - (89 of 148 people)
  • 40-49: 57.0% - (85 of 147 people)
  • 50-59: 51.0% - (69 of 134 people)
  • 60+: 55.0% - (39 of 70 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (3 of 6 people)
  • 20-29: 29.0% - (23 of 79 people)
  • 30-39: 32.0% - (46 of 140 people)
  • 40-49: 35.0% - (50 of 142 people)
  • 50-59: 37.0% - (48 of 129 people)
  • 60+: 37.0% - (25 of 67 people)

Most common drug interactions over time *:

< 1 month:
  • anxiety
  • depression
  • drug ineffective
  • nausea
  • convulsion
  • dizziness
  • fall
  • insomnia
  • suicidal ideation
  • suicide attempt
1 - 6 months:
  • drug exposure during pregnancy
  • cardiomegaly
  • congenital anomaly
  • dilatation ventricular
  • truncus arteriosus persistent
  • ventricular septal defect
  • bundle branch block right
  • depression
  • aortic stenosis
  • anxiety
6 - 12 months:
  • nausea
  • depression
  • type 2 diabetes mellitus
  • anxiety
  • back pain
  • headache
  • fatigue
  • anxiety disorder
  • insomnia
  • muscle spasms
1 - 2 years:
  • anxiety
  • type 2 diabetes mellitus
  • gastric ulcer
  • nausea
  • cardiac arrest
  • depression
  • headache
  • myocardial infarction
  • cardiac failure congestive
  • fatigue
2 - 5 years:
  • hair loss
  • depression
  • fatigue
  • nausea
  • anxiety
  • headache
  • type 2 diabetes mellitus
  • diabetes mellitus
  • anxiety disorder
  • constipation
5 - 10 years:
  • depression
  • nausea
  • anxiety
  • dizziness
  • irritability
  • intentional overdose
  • suicide attempt
  • pain
  • vision blurred
  • weight gain
10+ years:
  • depression
  • pain
  • fatigue
  • anxiety
  • dry mouth
  • angioedema
  • chest pain
  • swollen tongue
  • constipation
  • insomnia
not specified:
  • depression
  • anxiety
  • nausea
  • pain
  • drug ineffective
  • weight increased
  • fatigue
  • insomnia
  • dizziness
  • diabetes mellitus

Most common drug interactions by gender *:

female:
  • depression
  • anxiety
  • nausea
  • pain
  • drug ineffective
  • weight increased
  • headache
  • fatigue
  • dizziness
  • insomnia
male:
  • depression
  • anxiety
  • drug ineffective
  • diabetes mellitus
  • type 2 diabetes mellitus
  • fatigue
  • weight increased
  • insomnia
  • suicidal ideation
  • nausea

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • anhedonia
  • anxiety
  • attention deficit/hyperactivity disorder
  • cleft lip
  • congenital choroid plexus cyst
  • deep vein thrombosis
  • dysphagia
2-9:
  • dysphagia
  • laryngomalacia
  • speech disorder
  • hypertension
  • headache
  • weight decreased
  • drug exposure during pregnancy
  • abdominal distension
  • abdominal pain
  • abnormal behaviour
10-19:
  • nausea
  • vomiting
  • back pain
  • somnolence
  • biliary dyskinesia
  • cholecystitis chronic
  • drug abuse
  • gallbladder disorder
  • abdominal discomfort
  • abdominal pain upper
20-29:
  • hair loss
  • completed suicide
  • drug ineffective
  • convulsion
  • depression
  • grand mal convulsion
  • suicidal ideation
  • suicide attempt
  • pulmonary embolism
  • weight increased
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • anxiety
  • pain
  • completed suicide
  • depression
  • weight increased
  • dizziness
  • insomnia
40-49:
  • depression
  • nausea
  • anxiety
  • fatigue
  • pain
  • diabetes mellitus
  • dizziness
  • weight increased
  • drug ineffective
  • suicidal ideation
50-59:
  • depression
  • anxiety
  • fall
  • pain
  • nausea
  • fatigue
  • headache
  • insomnia
  • weight increased
  • type 2 diabetes mellitus
60+:
  • drug ineffective
  • fatigue
  • nausea
  • depression
  • dizziness
  • anxiety
  • headache
  • pain
  • asthenia
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Klonopin (clonazepam) is often used to treat stress and anxiety. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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