Review: taking Lamictal and Keppra xr together


Summary

Drug interactions are reported among people who take Lamictal and Keppra xr together. This review analyzes the effectiveness and drug interactions between Lamictal and Keppra xr. It is created by eHealthMe based on reports of 6,151 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 53,475 users)

Keppra Xr

Keppra xr has active ingredients of levetiracetam. It is often used in seizures. (latest outcomes from Keppra xr 1,320 users)

On Sep, 16, 2016

6,151 people who take Lamictal, Keppra Xr are studied.


Number of reports submitted per year:

Lamictal and Keppra xr drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 50.0% - (5 of 10 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 50.0% - (9 of 18 people)
  • 2 - 5 years: 45.0% - (17 of 37 people)
  • 5 - 10 years: 57.0% - (16 of 28 people)
  • 10+ years: 50.0% - (10 of 20 people)
  • not specified: 33.0% - (1 of 3 people)
Keppra Xr:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 63.0% - (7 of 11 people)
  • 6 - 12 months: 62.0% - (5 of 8 people)
  • 1 - 2 years: 29.0% - (5 of 17 people)
  • 2 - 5 years: 59.0% - (22 of 37 people)
  • 5 - 10 years: 70.0% - (19 of 27 people)
  • 10+ years: 57.0% - (11 of 19 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Lamictal:
  • female: 44.0% - (40 of 90 people)
  • male: 58.0% - (21 of 36 people)
Keppra Xr:
  • female: 56.0% - (50 of 88 people)
  • male: 56.0% - (22 of 39 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 33.0% - (1 of 3 people)
  • 10-19: 40.0% - (2 of 5 people)
  • 20-29: 44.0% - (15 of 34 people)
  • 30-39: 51.0% - (19 of 37 people)
  • 40-49: 40.0% - (6 of 15 people)
  • 50-59: 56.0% - (13 of 23 people)
  • 60+: 55.0% - (5 of 9 people)
Keppra Xr:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 33.0% - (1 of 3 people)
  • 10-19: 60.0% - (3 of 5 people)
  • 20-29: 51.0% - (18 of 35 people)
  • 30-39: 59.0% - (22 of 37 people)
  • 40-49: 64.0% - (9 of 14 people)
  • 50-59: 60.0% - (14 of 23 people)
  • 60+: 50.0% - (5 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • rash
  • convulsion
  • pyrexia
  • drug eruption
  • somnolence
  • dizziness
  • erythema
  • erythema multiforme
  • status epilepticus
  • drug ineffective
1 - 6 months:
  • convulsion
  • pyrexia
  • headache
  • rash
  • depression
  • dizziness
  • rash maculo-papular
  • foetal exposure during pregnancy
  • grand mal convulsion
  • maternal drugs affecting foetus
6 - 12 months:
  • foetal exposure during pregnancy
  • premature baby
  • neonatal respiratory distress syndrome
  • atrial septal defect
  • pyrexia
  • insomnia
  • respiratory distress
  • diarrhoea
  • irritability
  • jaundice
1 - 2 years:
  • insomnia
  • constipation
  • pyrexia
  • diarrhoea
  • road traffic accident
  • ammonia increased
  • atrial septal defect
  • autonomic nervous system imbalance
  • cough
  • crying
2 - 5 years:
  • convulsion
  • aggression
  • mood altered
  • thermal burn
  • rash
  • rhabdomyolysis
  • seizure
  • visual impairment
  • acute hepatic failure
  • pruritus
5 - 10 years:
  • convulsion
  • tremor
  • alopecia
  • diabetes mellitus
  • pancreatitis
  • urinary tract infection
  • weight decreased
  • aggression
  • chest pain
  • drug ineffective
10+ years:
  • seizure - grand mal
  • seizure - petit mal
  • inflammation
  • vicodin overdose
  • aches - leg
  • angiopathy
  • arthritis
  • blood creatinine increased
  • burning eyes
  • clumsiness
not specified:
  • convulsion
  • drug ineffective
  • seizure
  • fatigue
  • dizziness
  • depression
  • epilepsy
  • somnolence
  • grand mal convulsion
  • drug exposure during pregnancy

Most common drug interactions by gender *:

female:
  • convulsion
  • drug ineffective
  • seizure
  • dizziness
  • fatigue
  • pregnancy
  • depression
  • grand mal convulsion
  • epilepsy
  • drug exposure during pregnancy
male:
  • convulsion
  • drug ineffective
  • fatigue
  • seizure
  • fall
  • dizziness
  • somnolence
  • pyrexia
  • epilepsy
  • depression

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • premature baby
  • neonatal respiratory distress syndrome
  • maternal drugs affecting foetus
  • ventricular septal defect
  • atrial septal defect
  • drug exposure during pregnancy
  • low birth weight baby
  • convulsion
  • hypoglycaemia
2-9:
  • convulsion
  • drug ineffective
  • aggression
  • status epilepticus
  • abnormal behaviour
  • rash
  • epilepsy
  • seizure
  • thrombocytopenia
  • encephalopathy
10-19:
  • convulsion
  • epilepsy
  • grand mal convulsion
  • depression
  • drug ineffective
  • fatigue
  • aggression
  • thrombocytopenia
  • rash
  • dizziness
20-29:
  • convulsion
  • drug ineffective
  • nausea
  • grand mal convulsion
  • fatigue
  • seizure
  • vomiting
  • drug exposure during pregnancy
  • pregnancy
  • epilepsy
30-39:
  • convulsion
  • epilepsy
  • drug ineffective
  • fatigue
  • drug exposure during pregnancy
  • grand mal convulsion
  • depression
  • pyrexia
  • nausea
  • dizziness
40-49:
  • convulsion
  • drug ineffective
  • fatigue
  • dizziness
  • headache
  • rash
  • somnolence
  • grand mal convulsion
  • insomnia
  • nausea
50-59:
  • convulsion
  • fatigue
  • epilepsy
  • headache
  • urinary tract infection
  • dizziness
  • drug ineffective
  • somnolence
  • depression
  • confusional state
60+:
  • convulsion
  • dizziness
  • fall
  • drug ineffective
  • somnolence
  • confusional state
  • rash
  • depression
  • tremor
  • seizure

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Keppra xr (levetiracetam) is often used to treat seizures. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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