Review: taking Lamictal and Seroquel together


Summary

Drug interactions are reported among people who take Lamictal and Seroquel together. This review analyzes the effectiveness and drug interactions between Lamictal and Seroquel. It is created by eHealthMe based on reports of 7,061 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 53,475 users)

Seroquel

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 89,713 users)

On Sep, 17, 2016

7,061 people who take Lamictal, Seroquel are studied.


Number of reports submitted per year:

Lamictal and Seroquel drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 18.0% - (3 of 16 people)
  • 1 - 6 months: 29.0% - (22 of 75 people)
  • 6 - 12 months: 40.0% - (25 of 61 people)
  • 1 - 2 years: 47.0% - (34 of 71 people)
  • 2 - 5 years: 57.0% - (65 of 113 people)
  • 5 - 10 years: 56.0% - (44 of 78 people)
  • 10+ years: 68.0% - (17 of 25 people)
  • not specified: 75.0% - (3 of 4 people)
Seroquel:
  • < 1 month: 30.0% - (12 of 39 people)
  • 1 - 6 months: 40.0% - (36 of 88 people)
  • 6 - 12 months: 48.0% - (24 of 50 people)
  • 1 - 2 years: 49.0% - (37 of 75 people)
  • 2 - 5 years: 59.0% - (62 of 104 people)
  • 5 - 10 years: 59.0% - (43 of 72 people)
  • 10+ years: 78.0% - (15 of 19 people)
  • not specified: 80.0% - (4 of 5 people)

Drug effectiveness by gender:

Lamictal:
  • female: 49.0% - (161 of 326 people)
  • male: 44.0% - (52 of 117 people)
Seroquel:
  • female: 51.0% - (170 of 333 people)
  • male: 52.0% - (63 of 119 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 38.0% - (12 of 31 people)
  • 20-29: 55.0% - (55 of 99 people)
  • 30-39: 47.0% - (50 of 106 people)
  • 40-49: 41.0% - (46 of 111 people)
  • 50-59: 49.0% - (35 of 71 people)
  • 60+: 60.0% - (15 of 25 people)
Seroquel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 40.0% - (13 of 32 people)
  • 20-29: 51.0% - (53 of 103 people)
  • 30-39: 49.0% - (54 of 109 people)
  • 40-49: 52.0% - (58 of 110 people)
  • 50-59: 54.0% - (39 of 72 people)
  • 60+: 61.0% - (16 of 26 people)

Most common drug interactions over time *:

< 1 month:
  • rash
  • pyrexia
  • erythema
  • alanine aminotransferase increased
  • drug eruption
  • stevens-johnson syndrome
  • c-reactive protein increased
  • somnolence
  • malaise
  • dizziness
1 - 6 months:
  • rash
  • type 2 diabetes mellitus
  • diabetes mellitus
  • pyrexia
  • neuropathy peripheral
  • anxiety
  • weight increased
  • insomnia
  • depression
  • nausea
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • neuropathy peripheral
  • arthralgia
  • intraocular pressure increased
  • diabetic foot
  • chest pain
  • mental disorder
  • pneumonia
  • abdominal pain upper
1 - 2 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • depression
  • hyperglycaemia
  • obesity
  • anxiety
  • insomnia
  • drug ineffective
  • glycosuria
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • obesity
  • insomnia
  • blood cholesterol increased
  • depression
  • drug ineffective
  • diabetic neuropathy
  • headache
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • blood cholesterol increased
  • weight increased
  • insomnia
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • diabetic neuropathy
  • suicidal ideation
10+ years:
  • short-term memory loss
  • insomnia
  • acanthosis nigricans
  • cerebral palsy
  • dystonia
  • long-term memory loss
  • muscle spasticity
  • vomiting
  • type 2 diabetes mellitus
  • nausea
not specified:
  • insomnia
  • depression
  • drug ineffective
  • somnolence
  • fall
  • headache
  • diabetes mellitus
  • fatigue
  • weight increased
  • malaise

Most common drug interactions by gender *:

female:
  • insomnia
  • depression
  • drug ineffective
  • somnolence
  • type 2 diabetes mellitus
  • diabetes mellitus
  • fall
  • fatigue
  • headache
  • malaise
male:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • insomnia
  • weight increased
  • anxiety
  • somnolence
  • depression
  • headache
  • agitation
  • suicidal ideation

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • neonatal respiratory distress syndrome
  • drug withdrawal syndrome neonatal
  • agitation neonatal
  • atrial septal defect
  • convulsion
  • diabetes mellitus
  • haemangioma congenital
  • hypotonia
  • kidney duplex
2-9:
  • jaw disorder
  • throat irritation
  • tic
  • tremor
  • weight increased
  • bipolar disorder
  • drug ineffective
  • migraine
  • vomiting
  • rash
10-19:
  • type 2 diabetes mellitus
  • completed suicide
  • depression
  • rash
  • weight increased
  • suicidal ideation
  • diabetes mellitus
  • obesity
  • somnolence
  • pyrexia
20-29:
  • type 2 diabetes mellitus
  • rash
  • insomnia
  • abnormal behaviour
  • suicidal ideation
  • weight increased
  • diabetes mellitus
  • completed suicide
  • mania
  • somnolence
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • depression
  • weight increased
  • insomnia
  • obesity
  • nausea
  • headache
  • blood cholesterol increased
  • rash
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • insomnia
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • headache
  • depression
  • blood cholesterol increased
  • drug ineffective
50-59:
  • insomnia
  • diabetes mellitus
  • depression
  • type 2 diabetes mellitus
  • weight increased
  • somnolence
  • anxiety
  • bipolar disorder
  • tremor
  • malaise
60+:
  • insomnia
  • anxiety
  • depression
  • weight increased
  • somnolence
  • drug ineffective
  • malaise
  • fall
  • mania
  • nausea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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