Review: taking Lamictal and Seroquel together


Summary

Drug interactions are reported among people who take Lamictal and Seroquel together. This review analyzes the effectiveness and drug interactions between Lamictal and Seroquel. It is created by eHealthMe based on reports of 5,119 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 40,259 users)

Seroquel

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 74,191 users)

On Jul, 28, 2016

5,119 people who take Lamictal, Seroquel are studied.


Number of reports submitted per year:

Lamictal and Seroquel drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 18.0% - (3 of 16 people)
  • 1 - 6 months: 26.0% - (24 of 91 people)
  • 6 - 12 months: 40.0% - (30 of 75 people)
  • 1 - 2 years: 43.0% - (36 of 83 people)
  • 2 - 5 years: 61.0% - (85 of 138 people)
  • 5 - 10 years: 59.0% - (59 of 100 people)
  • 10+ years: 69.0% - (29 of 42 people)
  • not specified: 83.0% - (5 of 6 people)
Seroquel:
  • < 1 month: 31.0% - (15 of 47 people)
  • 1 - 6 months: 41.0% - (45 of 109 people)
  • 6 - 12 months: 44.0% - (28 of 63 people)
  • 1 - 2 years: 48.0% - (41 of 84 people)
  • 2 - 5 years: 56.0% - (75 of 132 people)
  • 5 - 10 years: 67.0% - (69 of 102 people)
  • 10+ years: 76.0% - (16 of 21 people)
  • not specified: 85.0% - (6 of 7 people)

Drug effectiveness by gender:

Lamictal:
  • female: 51.0% - (207 of 403 people)
  • male: 43.0% - (64 of 148 people)
Seroquel:
  • female: 52.0% - (217 of 414 people)
  • male: 51.0% - (78 of 151 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 47.0% - (20 of 42 people)
  • 20-29: 55.0% - (62 of 111 people)
  • 30-39: 51.0% - (68 of 132 people)
  • 40-49: 39.0% - (54 of 138 people)
  • 50-59: 48.0% - (47 of 97 people)
  • 60+: 63.0% - (19 of 30 people)
Seroquel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 32.0% - (14 of 43 people)
  • 20-29: 52.0% - (61 of 117 people)
  • 30-39: 52.0% - (70 of 133 people)
  • 40-49: 53.0% - (73 of 137 people)
  • 50-59: 57.0% - (57 of 100 people)
  • 60+: 55.0% - (19 of 34 people)

Most common drug interactions over time *:

< 1 month:
  • rash
  • pyrexia
  • erythema
  • stevens-johnson syndrome
  • alanine aminotransferase increased
  • drug eruption
  • c-reactive protein increased
  • diabetes mellitus
  • dyspnoea
  • colitis ischaemic
1 - 6 months:
  • type 2 diabetes mellitus
  • rash
  • diabetes mellitus
  • neuropathy peripheral
  • pyrexia
  • anxiety
  • weight increased
  • pneumonia
  • diabetes mellitus inadequate control
  • tremor
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • neuropathy peripheral
  • arthralgia
  • intraocular pressure increased
  • diabetic foot
  • chest pain
  • mental disorder
  • pneumonia
  • abdominal pain upper
1 - 2 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • hyperglycaemia
  • obesity
  • depression
  • anxiety
  • glycosuria
  • pancreatitis
  • blood triglycerides increased
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • obesity
  • blood cholesterol increased
  • diabetic neuropathy
  • diabetes mellitus inadequate control
  • neuropathy peripheral
  • arthralgia
  • pancreatitis
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • blood cholesterol increased
  • insomnia
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • diabetic neuropathy
  • suicidal ideation
  • weight increased
10+ years:
  • short-term memory loss
  • acanthosis nigricans
  • cerebral palsy
  • dystonia
  • long-term memory loss
  • muscle spasticity
  • type 2 diabetes mellitus
  • obesity
  • blood cholesterol increased
  • hyperlipidaemia
not specified:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • insomnia
  • weight increased
  • depression
  • somnolence
  • anxiety
  • headache
  • rash
  • agitation

Most common drug interactions by gender *:

female:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • weight increased
  • depression
  • anxiety
  • rash
  • somnolence
  • blood cholesterol increased
  • fatigue
male:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • insomnia
  • headache
  • neuropathy peripheral
  • agitation
  • somnolence
  • diabetes mellitus inadequate control
  • suicidal ideation

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • blood cholesterol increased
  • hyperlipidaemia
  • arthritis
  • blood triglycerides increased
  • cerebrovascular accident
  • convulsion
  • diabetic neuropathy
  • dyspnoea
  • haematochezia
2-9:
  • jaw disorder
  • throat irritation
  • tic
  • tremor
  • weight increased
  • drug ineffective
  • rash
  • suicidal ideation
  • bipolar disorder
  • convulsion
10-19:
  • type 2 diabetes mellitus
  • rash
  • diabetes mellitus
  • suicidal ideation
  • completed suicide
  • obesity
  • depression
  • weight increased
  • diabetic ketoacidosis
  • hyperglycaemia
20-29:
  • type 2 diabetes mellitus
  • rash
  • weight increased
  • diabetes mellitus
  • abnormal behaviour
  • insomnia
  • mania
  • suicidal ideation
  • diabetic neuropathy
  • blood cholesterol increased
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • obesity
  • insomnia
  • blood cholesterol increased
  • suicide attempt
  • nausea
  • rash
  • depression
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • neuropathy peripheral
  • insomnia
  • diabetes mellitus inadequate control
  • headache
  • blood cholesterol increased
  • agitation
  • depression
50-59:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • insomnia
  • depression
  • weight increased
  • anxiety
  • somnolence
  • amnesia
  • memory impairment
  • convulsion
60+:
  • insomnia
  • anxiety
  • fall
  • depression
  • somnolence
  • malaise
  • tardive dyskinesia
  • speech disorder
  • pyrexia
  • parkinsonism

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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