Review: taking Lamictal and Seroquel together


Summary

Drug interactions are reported among people who take Lamictal and Seroquel together. This review analyzes the effectiveness and drug interactions between Lamictal and Seroquel. It is created by eHealthMe based on reports of 5,661 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 42,143 users)

Seroquel

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 77,696 users)

On Aug, 17, 2016

5,661 people who take Lamictal, Seroquel are studied.


Number of reports submitted per year:

Lamictal and Seroquel drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 18.0% - (3 of 16 people)
  • 1 - 6 months: 29.0% - (22 of 75 people)
  • 6 - 12 months: 40.0% - (25 of 61 people)
  • 1 - 2 years: 47.0% - (35 of 73 people)
  • 2 - 5 years: 57.0% - (64 of 112 people)
  • 5 - 10 years: 56.0% - (44 of 78 people)
  • 10+ years: 68.0% - (17 of 25 people)
  • not specified: 75.0% - (3 of 4 people)
Seroquel:
  • < 1 month: 30.0% - (12 of 39 people)
  • 1 - 6 months: 40.0% - (36 of 88 people)
  • 6 - 12 months: 48.0% - (24 of 50 people)
  • 1 - 2 years: 49.0% - (37 of 75 people)
  • 2 - 5 years: 59.0% - (62 of 105 people)
  • 5 - 10 years: 60.0% - (43 of 71 people)
  • 10+ years: 78.0% - (15 of 19 people)
  • not specified: 80.0% - (4 of 5 people)

Drug effectiveness by gender:

Lamictal:
  • female: 49.0% - (161 of 327 people)
  • male: 44.0% - (52 of 117 people)
Seroquel:
  • female: 51.0% - (170 of 333 people)
  • male: 52.0% - (63 of 119 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 38.0% - (12 of 31 people)
  • 20-29: 55.0% - (55 of 99 people)
  • 30-39: 46.0% - (50 of 107 people)
  • 40-49: 41.0% - (46 of 111 people)
  • 50-59: 49.0% - (35 of 71 people)
  • 60+: 60.0% - (15 of 25 people)
Seroquel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 40.0% - (13 of 32 people)
  • 20-29: 51.0% - (53 of 103 people)
  • 30-39: 49.0% - (54 of 109 people)
  • 40-49: 52.0% - (58 of 110 people)
  • 50-59: 54.0% - (39 of 72 people)
  • 60+: 61.0% - (16 of 26 people)

Most common drug interactions over time *:

< 1 month:
  • rash
  • pyrexia
  • erythema
  • stevens-johnson syndrome
  • alanine aminotransferase increased
  • c-reactive protein increased
  • drug eruption
  • diabetes mellitus
  • malaise
  • rash generalised
1 - 6 months:
  • type 2 diabetes mellitus
  • rash
  • diabetes mellitus
  • neuropathy peripheral
  • pyrexia
  • anxiety
  • weight increased
  • chest pain
  • insomnia
  • nausea
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • neuropathy peripheral
  • arthralgia
  • intraocular pressure increased
  • diabetic foot
  • chest pain
  • mental disorder
  • pneumonia
  • abdominal pain upper
1 - 2 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • hyperglycaemia
  • obesity
  • anxiety
  • depression
  • glycosuria
  • pancreatitis
  • blood triglycerides increased
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • obesity
  • blood cholesterol increased
  • diabetic neuropathy
  • diabetes mellitus inadequate control
  • neuropathy peripheral
  • insomnia
  • arthralgia
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • blood cholesterol increased
  • insomnia
  • neuropathy peripheral
  • weight increased
  • diabetes mellitus inadequate control
  • diabetic neuropathy
  • suicidal ideation
10+ years:
  • short-term memory loss
  • acanthosis nigricans
  • cerebral palsy
  • dystonia
  • long-term memory loss
  • muscle spasticity
  • type 2 diabetes mellitus
  • obesity
  • vomiting
  • blood cholesterol increased
not specified:
  • insomnia
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • depression
  • somnolence
  • anxiety
  • headache
  • drug ineffective
  • convulsion

Most common drug interactions by gender *:

female:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • weight increased
  • depression
  • somnolence
  • anxiety
  • rash
  • fatigue
  • convulsion
male:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • weight increased
  • anxiety
  • headache
  • somnolence
  • agitation
  • neuropathy peripheral
  • suicidal ideation

Most common drug interactions by age *:

0-1:
  • neonatal respiratory distress syndrome
  • diabetes mellitus
  • acute respiratory distress syndrome
  • atrial septal defect
  • blood cholesterol increased
  • coarctation of the aorta
  • congenital aortic valve stenosis
  • congenital emphysema
  • convulsion
  • hyperlipidaemia
2-9:
  • jaw disorder
  • throat irritation
  • tic
  • tremor
  • weight increased
  • bipolar disorder
  • drug ineffective
  • migraine
  • vomiting
  • rash
10-19:
  • type 2 diabetes mellitus
  • rash
  • weight increased
  • diabetes mellitus
  • obesity
  • suicidal ideation
  • completed suicide
  • depression
  • diabetic ketoacidosis
  • hyperglycaemia
20-29:
  • type 2 diabetes mellitus
  • rash
  • weight increased
  • abnormal behaviour
  • insomnia
  • diabetes mellitus
  • mania
  • suicidal ideation
  • somnolence
  • blood cholesterol increased
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • insomnia
  • weight increased
  • obesity
  • blood cholesterol increased
  • suicide attempt
  • nausea
  • rash
  • headache
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • neuropathy peripheral
  • insomnia
  • diabetes mellitus inadequate control
  • headache
  • blood cholesterol increased
  • depression
  • agitation
50-59:
  • diabetes mellitus
  • insomnia
  • type 2 diabetes mellitus
  • weight increased
  • depression
  • anxiety
  • somnolence
  • memory impairment
  • tremor
  • convulsion
60+:
  • insomnia
  • anxiety
  • malaise
  • depression
  • fall
  • weight increased
  • tachyphrenia
  • somnolence
  • bipolar disorder
  • mania

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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