Review: taking Lamictal and Zyrtec together


Summary

Drug interactions are reported among people who take Lamictal and Zyrtec together. This review analyzes the effectiveness and drug interactions between Lamictal and Zyrtec. It is created by eHealthMe based on reports of 570 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 45,312 users)

Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 34,371 users)

On Aug, 27, 2016

570 people who take Lamictal, Zyrtec are studied.


Number of reports submitted per year:

Lamictal and Zyrtec drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 37.0% - (3 of 8 people)
  • 6 - 12 months: 60.0% - (3 of 5 people)
  • 1 - 2 years: 41.0% - (5 of 12 people)
  • 2 - 5 years: 53.0% - (7 of 13 people)
  • 5 - 10 years: 60.0% - (6 of 10 people)
  • 10+ years: 100.0% - (5 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Zyrtec:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 40.0% - (2 of 5 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 63.0% - (7 of 11 people)
  • 5 - 10 years: 62.0% - (5 of 8 people)
  • 10+ years: 85.0% - (6 of 7 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lamictal:
  • female: 59.0% - (26 of 44 people)
  • male: 27.0% - (3 of 11 people)
Zyrtec:
  • female: 47.0% - (19 of 40 people)
  • male: 60.0% - (6 of 10 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 2 people)
  • 10-19: 40.0% - (2 of 5 people)
  • 20-29: 58.0% - (7 of 12 people)
  • 30-39: 50.0% - (7 of 14 people)
  • 40-49: 58.0% - (7 of 12 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 66.0% - (2 of 3 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 60.0% - (3 of 5 people)
  • 20-29: 60.0% - (6 of 10 people)
  • 30-39: 21.0% - (3 of 14 people)
  • 40-49: 81.0% - (9 of 11 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • stevens-johnson syndrome
  • erythema
  • pyrexia
  • rash
  • c-reactive protein increased
  • lymphocyte percentage decreased
  • monocyte percentage increased
  • neutrophil percentage increased
  • rash generalised
  • generalised erythema
1 - 6 months:
  • fatigue
  • nausea
  • psoriasis
  • pyrexia
  • rash
  • stevens-johnson syndrome
  • breast cancer metastatic
  • c-reactive protein increased
  • dizziness
  • eczema
6 - 12 months:
  • rash
  • alopecia
  • anger
  • asthenia
  • back pain
  • barium swallow abnormal
  • body height increased
  • bone disorder
  • cough
  • depression
1 - 2 years:
  • bronchitis acute
  • irregular heartbeat
  • headache
  • anxiety
  • convulsion
  • fatigue
  • influenza
  • mood swings
  • nasopharyngitis
  • staphylococcal infection
2 - 5 years:
  • epilepsy
  • complex partial seizures
  • abdominal pain
  • diarrhoea
  • bronchitis acute
  • dyspepsia
  • fatigue
  • irregular heartbeat
  • nausea
  • rash
5 - 10 years:
  • anxiety
  • blepharitis
  • bronchospasm
  • chest discomfort
  • complex partial seizures
  • night sweats
  • vision blurred
  • abdominal discomfort
  • aggression aggravated
  • anal candidiasis
10+ years:
  • drowsiness
  • glaucoma
  • headache
  • high blood pressure
  • lack of strength, muscle weakness, weakness
not specified:
  • rash
  • depression
  • headache
  • nausea
  • dizziness
  • anxiety
  • fatigue
  • pain
  • insomnia
  • drug ineffective

Most common drug interactions by gender *:

female:
  • headache
  • rash
  • nausea
  • depression
  • dizziness
  • fatigue
  • anxiety
  • pain
  • insomnia
  • pruritus
male:
  • convulsion
  • rash
  • exomphalos
  • depression
  • drug ineffective
  • asthenia
  • pyrexia
  • erythema
  • alanine aminotransferase increased
  • maternal drugs affecting foetus

Most common drug interactions by age *:

2-9:
  • convulsion
  • drug administration error
  • rash
  • somnolence
  • anorexia
  • application site erythema
  • application site urticaria
  • asthenia
  • disturbance in attention
  • disturbance in social behaviour
10-19:
  • abortion spontaneous
  • metrorrhagia
  • hypotension
  • unintended pregnancy
  • convulsion
  • pregnancy with implant contraceptive
  • hypertension
  • maternal exposure during pregnancy
  • pregnancy with contraceptive device
  • pregnancy
20-29:
  • epilepsy
  • anxiety
  • hypersensitivity
  • nausea
  • fatigue
  • asthma
  • alopecia
  • back pain
  • headache
  • abdominal pain
30-39:
  • rash
  • rash generalised
  • headache
  • stevens-johnson syndrome
  • abdominal pain
  • depression
  • nausea
  • eye pruritus
  • eye swelling
  • scab
40-49:
  • headache
  • pruritus
  • rash
  • renal failure acute
  • pain
  • lactic acidosis
  • nausea
  • palpitations
  • septic shock
  • dizziness
50-59:
  • rash
  • depression
  • dizziness
  • nausea
  • headache
  • pyrexia
  • fatigue
  • pain
  • vomiting
  • bronchitis
60+:
  • headache
  • pain
  • fall
  • confusional state
  • rash
  • pain in extremity
  • cardiac failure congestive
  • diarrhoea
  • dizziness
  • drug ineffective

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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