Review: taking Lamictal and Zyrtec together


Summary

Drug interactions are reported among people who take Lamictal and Zyrtec together. This review analyzes the effectiveness and drug interactions between Lamictal and Zyrtec. It is created by eHealthMe based on reports of 452 people who take the same drugs from FDA and social media, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 40,254 users)

Zyrtec

Zyrtec has active ingredients of cetirizine. It is often used in hypersensitivity. (latest outcomes from Zyrtec 30,543 users)

On Jul, 20, 2016

452 people who take Lamictal, Zyrtec are studied.


Number of reports submitted per year:

Lamictal and Zyrtec drug interactions.

Drug effectiveness over time:

Lamictal:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 40.0% - (4 of 10 people)
  • 6 - 12 months: 60.0% - (3 of 5 people)
  • 1 - 2 years: 41.0% - (5 of 12 people)
  • 2 - 5 years: 43.0% - (7 of 16 people)
  • 5 - 10 years: 63.0% - (7 of 11 people)
  • 10+ years: 100.0% - (6 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Zyrtec:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 9.0% - (1 of 11 people)
  • 2 - 5 years: 61.0% - (8 of 13 people)
  • 5 - 10 years: 62.0% - (5 of 8 people)
  • 10+ years: 85.0% - (6 of 7 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lamictal:
  • female: 56.0% - (29 of 51 people)
  • male: 27.0% - (3 of 11 people)
Zyrtec:
  • female: 43.0% - (20 of 46 people)
  • male: 60.0% - (6 of 10 people)

Drug effectiveness by age:

Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 2 people)
  • 10-19: 40.0% - (2 of 5 people)
  • 20-29: 61.0% - (8 of 13 people)
  • 30-39: 38.0% - (7 of 18 people)
  • 40-49: 61.0% - (8 of 13 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 75.0% - (3 of 4 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 60.0% - (3 of 5 people)
  • 20-29: 54.0% - (6 of 11 people)
  • 30-39: 16.0% - (3 of 18 people)
  • 40-49: 81.0% - (9 of 11 people)
  • 50-59: 42.0% - (3 of 7 people)
  • 60+: 66.0% - (2 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • stevens-johnson syndrome
  • rash
  • erythema
  • c-reactive protein increased
  • lymphocyte percentage decreased
  • monocyte percentage increased
  • neutrophil percentage increased
  • eosinophil percentage decreased
  • generalised erythema
1 - 6 months:
  • fatigue
  • nausea
  • psoriasis
  • pyrexia
  • rash
  • c-reactive protein increased
  • dizziness
  • eczema
  • eosinophil percentage decreased
  • erythema
6 - 12 months:
  • rash
  • alopecia
  • anger
  • asthenia
  • back pain
  • barium swallow abnormal
  • body height increased
  • bone disorder
  • cough
  • depression
1 - 2 years:
  • bronchitis acute
  • irregular heartbeat
  • headache
  • convulsion
  • fatigue
  • influenza
  • mood swings
  • nasopharyngitis
  • staphylococcal infection
  • weight gain poor
2 - 5 years:
  • epilepsy
  • complex partial seizures
  • bronchitis acute
  • irregular heartbeat
  • nausea
  • abdominal discomfort
  • abdominal pain
  • abdominal pain upper
  • biliary dyskinesia
  • cholecystitis chronic
5 - 10 years:
  • blepharitis
  • complex partial seizures
  • depression
  • disorientation
  • dry eyes aggravated
  • night sweats
  • abdominal discomfort
  • aggression aggravated
  • anal candidiasis
  • anxiety
10+ years:
  • drowsiness
  • glaucoma
  • headache
  • high blood pressure
  • lack of strength, muscle weakness, weakness
not specified:
  • rash
  • headache
  • nausea
  • depression
  • dizziness
  • fatigue
  • anxiety
  • insomnia
  • pruritus
  • drug ineffective

Most common drug interactions by gender *:

female:
  • headache
  • nausea
  • rash
  • depression
  • dizziness
  • fatigue
  • anxiety
  • insomnia
  • epilepsy
  • constipation
male:
  • rash
  • exomphalos
  • convulsion
  • pyrexia
  • depression
  • alanine aminotransferase increased
  • asthenia
  • maternal drugs affecting foetus
  • aspartate aminotransferase increased
  • blister

Most common drug interactions by age *:

2-9:
  • convulsion
  • drug administration error
  • rash
  • somnolence
  • anorexia
  • application site erythema
  • application site urticaria
  • asthenia
  • disturbance in attention
  • disturbance in social behaviour
10-19:
  • hypotension
  • hospitalisation
  • hypertension
  • iron deficiency anaemia
  • tachycardia
  • cholecystitis
  • depression
  • psoriasis
  • fall
  • tremor
20-29:
  • epilepsy
  • nausea
  • asthma
  • anxiety
  • fatigue
  • headache
  • hypersensitivity
  • drug ineffective
  • suicide attempt
  • weight increased
30-39:
  • rash
  • headache
  • abdominal pain
  • nausea
  • depression
  • stevens-johnson syndrome
  • bronchitis acute
  • dizziness
  • fatigue
  • insomnia
40-49:
  • headache
  • lactic acidosis
  • nausea
  • pruritus
  • renal failure acute
  • septic shock
  • rash
  • convulsion
  • dizziness
  • feeling abnormal
50-59:
  • rash
  • depression
  • nausea
  • pyrexia
  • headache
  • dizziness
  • vomiting
  • diarrhoea
  • fatigue
  • pain
60+:
  • cardiac failure congestive
  • headache
  • fall
  • diarrhoea
  • insomnia
  • nausea
  • neuropathy peripheral
  • pain
  • rash
  • swelling

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Zyrtec (cetirizine) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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