Review: taking Lamotrigine and Benadryl together


Summary

Drug interactions are reported among people who take Lamotrigine and Benadryl together. This review analyzes the effectiveness and drug interactions between Lamotrigine and Benadryl. It is created by eHealthMe based on reports of 592 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Lamotrigine and Benadryl >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Lamotrigine

Lamotrigine has active ingredients of lamotrigine. It is often used in epilepsy. (latest outcomes from Lamotrigine 18,891 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 32,636 users)

On Aug, 23, 2016

592 people who take Lamotrigine, Benadryl are studied.


Number of reports submitted per year:

Lamotrigine and Benadryl drug interactions.

Drug effectiveness over time:

Lamotrigine:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 7.0% - (1 of 13 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 33.0% - (3 of 9 people)
  • 2 - 5 years: 50.0% - (7 of 14 people)
  • 5 - 10 years: 85.0% - (6 of 7 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 100.0% - (1 of 1 people)
Benadryl:
  • < 1 month: 37.0% - (6 of 16 people)
  • 1 - 6 months: 44.0% - (4 of 9 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 18.0% - (2 of 11 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 66.0% - (2 of 3 people)

Drug effectiveness by gender:

Lamotrigine:
  • female: 31.0% - (14 of 45 people)
  • male: 54.0% - (6 of 11 people)
Benadryl:
  • female: 38.0% - (17 of 44 people)
  • male: 44.0% - (4 of 9 people)

Drug effectiveness by age:

Lamotrigine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 5 people)
  • 20-29: 12.0% - (1 of 8 people)
  • 30-39: 40.0% - (6 of 15 people)
  • 40-49: 35.0% - (6 of 17 people)
  • 50-59: 85.0% - (6 of 7 people)
  • 60+: 25.0% - (1 of 4 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 4 people)
  • 20-29: 16.0% - (1 of 6 people)
  • 30-39: 40.0% - (6 of 15 people)
  • 40-49: 47.0% - (8 of 17 people)
  • 50-59: 57.0% - (4 of 7 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • blood bilirubin increased
  • engraftment syndrome
  • renal failure acute
  • rash
  • insomnia
  • pain
  • pruritus
  • pyrexia
  • sensory disturbance
  • acute graft versus host disease in liver
1 - 6 months:
  • rash
  • urticaria
  • asthenia
  • depression
  • dizziness
  • dystonia
  • muscle twitching
  • pruritus
  • vision blurred
  • abasia
6 - 12 months:
  • rash
  • depression
  • diarrhoea
  • feeling abnormal
  • hallucination, visual
  • pruritus
  • blister
  • bone loss
  • pain
  • rash pustular
1 - 2 years:
  • dizziness
  • diabetes mellitus
  • headache
  • numbness and tingling
  • oxygen saturation decreased
  • type 2 diabetes mellitus
  • agitation
  • anhedonia
  • arthritis
  • cystitis
2 - 5 years:
  • abdominal discomfort
  • abdominal pain
  • abdominal pain upper
  • aggression aggravated
  • agitation aggravated
  • anger
  • arthritis
  • biliary dyskinesia
  • breast enlargement
  • breast pain
5 - 10 years:
  • heart rate irregular
  • hives
  • implant site bruising
  • dizziness
  • headache
  • numbness and tingling
  • oxygen saturation decreased
  • rash pustular
  • angioedema
  • drowsiness
10+ years:
  • confusion
  • forgetfulness
  • lower blood pressure
not specified:
  • completed suicide
  • rash
  • pain
  • nausea
  • convulsion
  • depression
  • headache
  • confusional state
  • pruritus
  • vomiting

Most common drug interactions by gender *:

female:
  • rash
  • nausea
  • pain
  • depression
  • pruritus
  • convulsion
  • headache
  • back pain
  • pyrexia
  • completed suicide
male:
  • completed suicide
  • rash
  • weight increased
  • pneumonia
  • somnolence
  • agitation
  • dyspnoea
  • gait disturbance
  • headache
  • incontinence

Most common drug interactions by age *:

2-9:
  • petit mal epilepsy
10-19:
  • suicidal ideation
  • weight increased
  • akathisia
  • pyrexia
  • agitation
  • dyspepsia
  • gait disturbance
  • mania
  • excoriation
  • rash
20-29:
  • completed suicide
  • rash
  • convulsion
  • diarrhoea
  • feeling abnormal
  • abdominal pain
  • depression
  • nausea
  • urticaria
  • dizziness
30-39:
  • completed suicide
  • headache
  • vomiting
  • convulsion
  • loss of consciousness
  • rash
  • dizziness
  • type 2 diabetes mellitus
  • agitation
  • amnesia
40-49:
  • rash
  • pruritus
  • headache
  • mental disorder
  • coma
  • confusional state
  • fatigue
  • nausea
  • depression
  • dizziness
50-59:
  • completed suicide
  • pain
  • depression
  • meningitis aseptic
  • rash
  • fall
  • fatigue
  • mood swings
  • weight increased
  • pancreatitis
60+:
  • back pain
  • pain in extremity
  • pyrexia
  • anxiety
  • convulsion
  • swelling
  • neck pain
  • confusional state
  • headache
  • neuropathy peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lamotrigine and Benadryl?

Can you answer these questions?

More questions for: Lamotrigine, Benadryl

You may be interested in these reviews

More reviews for: Lamotrigine, Benadryl

On eHealthMe, Lamotrigine (lamotrigine) is often used to treat epilepsy. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.