Review: taking Lansoprazole and Hctz together


Summary

Drug interactions are reported among people who take Lansoprazole and Hctz together. This review analyzes the effectiveness and drug interactions between Lansoprazole and Hctz. It is created by eHealthMe based on reports of 2,980 people who take the same drugs from FDA and social media, and is updated regularly.

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Lansoprazole

Lansoprazole has active ingredients of lansoprazole. It is often used in gastrooesophageal reflux disease. (latest outcomes from Lansoprazole 49,709 users)

Hctz

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. (latest outcomes from Hctz 8,380 users)

On Sep, 17, 2016

2,980 people who take Lansoprazole, Hctz are studied.


Number of reports submitted per year:

Lansoprazole and Hctz drug interactions.

Drug effectiveness over time:

Lansoprazole:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 57.0% - (4 of 7 people)
  • 2 - 5 years: 80.0% - (8 of 10 people)
  • 5 - 10 years: 83.0% - (5 of 6 people)
  • 10+ years: 100.0% - (7 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Hctz:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 4 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 37.0% - (3 of 8 people)
  • 2 - 5 years: 20.0% - (1 of 5 people)
  • 5 - 10 years: 14.0% - (1 of 7 people)
  • 10+ years: 50.0% - (3 of 6 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Lansoprazole:
  • female: 70.0% - (17 of 24 people)
  • male: 76.0% - (10 of 13 people)
Hctz:
  • female: 29.0% - (7 of 24 people)
  • male: 23.0% - (3 of 13 people)

Drug effectiveness by age:

Lansoprazole:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 83.0% - (5 of 6 people)
  • 50-59: 77.0% - (7 of 9 people)
  • 60+: 66.0% - (14 of 21 people)
Hctz:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 60.0% - (3 of 5 people)
  • 50-59: 30.0% - (3 of 10 people)
  • 60+: 18.0% - (4 of 22 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • pyrexia
  • hypokalaemia
  • oedema peripheral
  • oxygen saturation decreased
  • tachycardia
  • blood creatinine increased
  • hyponatraemia
  • asthenia
  • dehydration
1 - 6 months:
  • fall
  • confusional state
  • hyponatraemia
  • back pain
  • bacterial sepsis
  • fatigue
  • head injury
  • hypokalaemia
  • hypomagnesaemia
  • mental status changes
6 - 12 months:
  • carpal tunnel syndrome
  • osteoporosis
  • abdominal pain
  • hyperamylasaemia
  • hypertension
  • hypothyroidism
  • intervertebral disc protrusion
  • multiple fractures
  • pancreatitis
  • anxiety
1 - 2 years:
  • deep vein thrombosis
  • pulmonary embolism
  • fatigue
  • tongue coated
  • abdominal pain
  • anaemia
  • arthralgia
  • bronchiectasis
  • confusional state
  • constipation
2 - 5 years:
  • depression
  • dyspnoea
  • pain in extremity
  • anxiety
  • chest pain
  • deep vein thrombosis
  • oedema peripheral
  • osteoporosis
  • bone disorder
  • cellulitis staphylococcal
5 - 10 years:
  • anxiety
  • chest pain
  • depression
  • back pain
  • bone disorder
  • cardiac disorder
  • diarrhoea
  • fall
  • impaired healing
  • multiple fractures
10+ years:
  • atrial fibrillation
  • back pain - low
  • bronchiectasis
  • cardiac arrest
  • disseminated intravascular coagulation
  • enterococcal infection
  • escherichia infection
  • headache
  • hiatus hernia
  • metastatic neoplasm
not specified:
  • nausea
  • pain
  • dyspnoea
  • fatigue
  • anxiety
  • diarrhoea
  • chest pain
  • depression
  • anaemia
  • hypertension

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • fatigue
  • dyspnoea
  • diarrhoea
  • fall
  • anxiety
  • chest pain
  • hypertension
  • depression
male:
  • pain
  • nausea
  • anaemia
  • depression
  • dyspnoea
  • anxiety
  • arthralgia
  • chest pain
  • asthenia
  • fatigue

Most common drug interactions by age *:

0-1:
  • acute respiratory failure
  • arthritis
  • arthropathy
  • back disorder
  • bronchopulmonary dysplasia
  • convulsion
  • depression
  • dyspnoea
  • fall
  • flatulence
2-9:
  • depression
  • multiple fractures
  • osteonecrosis
  • osteoporosis
  • pain in extremity
  • ruptured cerebral aneurysm
  • scoliosis
  • foetal exposure during pregnancy
  • foot fracture
  • renal failure
10-19:
  • back pain
  • chest pain
  • infectious pleural effusion
  • injection site extravasation
  • injection site haemorrhage
  • musculoskeletal chest pain
  • pancreatitis
  • pleural effusion
  • pneumonia
  • agitation
20-29:
  • gastrooesophageal reflux disease
  • nausea
  • abdominal pain
  • chest pain
  • cholecystitis chronic
  • diabetes mellitus
  • urinary tract infection
  • biliary colic
  • diarrhoea
  • eating disorder
30-39:
  • vomiting
  • chest pain
  • deep vein thrombosis
  • nausea
  • pulmonary embolism
  • depression
  • pain
  • dyspnoea
  • hypertension
  • diabetes mellitus
40-49:
  • nausea
  • pain
  • chest pain
  • depression
  • dyspnoea
  • anxiety
  • gastrooesophageal reflux disease
  • fatigue
  • constipation
  • fall
50-59:
  • nausea
  • pain
  • anxiety
  • depression
  • diarrhoea
  • fatigue
  • anaemia
  • hypertension
  • arthralgia
  • constipation
60+:
  • nausea
  • fatigue
  • dyspnoea
  • diarrhoea
  • anaemia
  • fall
  • pain
  • anxiety
  • vomiting
  • hypertension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lansoprazole (lansoprazole) is often used to treat gastrooesophageal reflux disease. Hctz (hydrochlorothiazide) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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