Review: taking Levaquin and Valtrex together


Summary

Drug interactions are reported among people who take Levaquin and Valtrex together. This review analyzes the effectiveness and drug interactions between Levaquin and Valtrex. It is created by eHealthMe based on reports of 652 people who take the same drugs from FDA and social media, and is updated regularly.

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Levaquin

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. (latest outcomes from Levaquin 28,497 users)

Valtrex

Valtrex has active ingredients of valacyclovir. It is often used in herpes zoster. (latest outcomes from Valtrex 16,244 users)

On Jul, 19, 2016

652 people who take Levaquin, Valtrex are studied.


Number of reports submitted per year:

Levaquin and Valtrex drug interactions.

Drug effectiveness over time:

Levaquin:
  • < 1 month: 57.0% - (4 of 7 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Valtrex:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Levaquin:
  • female: 42.0% - (3 of 7 people)
  • male: 50.0% - (1 of 2 people)
Valtrex:
  • female: 66.0% - (4 of 6 people)
  • male: 100.0% - (3 of 3 people)

Drug effectiveness by age:

Levaquin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 100.0% - (1 of 1 people)
Valtrex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 66.0% - (2 of 3 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 100.0% - (3 of 3 people)
  • 60+: 100.0% - (1 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • acute graft versus host disease
  • drug rash with eosinophilia and systemic symptoms
  • hepatitis cholestatic
  • renal failure
  • pyrexia
  • headache
  • nausea
  • febrile neutropenia
  • pneumonia
  • sepsis
1 - 6 months:
  • pneumonia
  • disseminated intravascular coagulation
  • white blood cell count decreased
  • blood glucose increased
  • liver disorder
  • platelet count decreased
  • pyrexia
  • oral herpes
  • c-reactive protein increased
  • anaemia
6 - 12 months:
  • cholecystitis
  • cholelithiasis
  • disseminated intravascular coagulation
  • duodenal ulcer
  • febrile neutropenia
  • hypoalbuminaemia
  • malignant neoplasm of renal pelvis
  • neuropathy peripheral
  • neutropenia
  • palpitations
1 - 2 years:
  • cerebellar infarction
  • cerebral infarction
  • dyskinesia
  • hemianopia homonymous
  • hemicephalalgia
  • hemiparesis
  • nausea
  • visual acuity reduced
  • vomiting
  • acne
2 - 5 years:
  • anxiety
  • cholelithiasis
  • vomiting
  • anhedonia
  • chest pain
  • cholecystitis chronic
  • deep vein thrombosis
  • dyspnoea
  • emotional distress
  • hyperhidrosis
not specified:
  • anxiety
  • pain
  • injury
  • nausea
  • fall
  • vomiting
  • osteonecrosis of jaw
  • pyrexia
  • pain in jaw
  • back pain

Most common drug interactions by gender *:

female:
  • anxiety
  • pain
  • injury
  • nausea
  • vomiting
  • pyrexia
  • fall
  • emotional distress
  • osteonecrosis of jaw
  • bone disorder
male:
  • anaemia
  • pancytopenia
  • anxiety
  • pain
  • hypokalaemia
  • nausea
  • pneumonia
  • injury
  • febrile neutropenia
  • thrombocytopenia

Most common drug interactions by age *:

10-19:
  • activated partial thromboplastin time prolonged
  • ascites
  • aspartate aminotransferase increased
  • blood bilirubin increased
  • blood lactate dehydrogenase increased
  • abdominal discomfort
  • abdominal pain upper
  • adenovirus infection
  • adverse drug reaction
  • blood pressure fluctuation
20-29:
  • nausea
  • vomiting
  • headache
  • hyperbilirubinaemia
  • chest pain
  • deep vein thrombosis
  • dyspnoea
  • febrile neutropenia
  • cerebellar infarction
  • cerebral infarction
30-39:
  • pain
  • anxiety
  • cholecystitis chronic
  • diabetes mellitus
  • nausea
  • anaemia
  • cholelithiasis
  • deep vein thrombosis
  • fear
  • gallbladder disorder
40-49:
  • arthralgia
  • back pain
  • pain
  • anxiety
  • asthenia
  • diarrhoea
  • dyskinesia
  • emotional distress
  • gastrooesophageal reflux disease
  • haemorrhoids
50-59:
  • pyrexia
  • pain
  • anxiety
  • nausea
  • injury
  • osteoarthritis
  • pain in jaw
  • vomiting
  • hypoaesthesia
  • osteonecrosis of jaw
60+:
  • anxiety
  • pain
  • fall
  • injury
  • pneumonia
  • anaemia
  • thrombocytopenia
  • bone disorder
  • hypokalaemia
  • pyrexia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Levaquin (levofloxacin) is often used to treat sinusitis. Valtrex (valacyclovir) is often used to treat herpes zoster. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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