Review: taking Levetiracetam and Melatonin together


Summary

Drug interactions are reported among people who take Levetiracetam and Melatonin together. This review analyzes the effectiveness and drug interactions between Levetiracetam and Melatonin. It is created by eHealthMe based on reports of 76 people who take the same drugs from FDA and social media, and is updated regularly.

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Levetiracetam

Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. (latest outcomes from Levetiracetam 5,586 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 3,072 users)

On Jul, 27, 2016

76 people who take Levetiracetam, Melatonin are studied.


Number of reports submitted per year:

Levetiracetam and Melatonin drug interactions.

Drug effectiveness over time:

Levetiracetam:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Levetiracetam:
  • female: 20.0% - (1 of 5 people)
  • male: 66.0% - (2 of 3 people)
Melatonin:
  • female: 20.0% - (1 of 5 people)
  • male: 33.0% - (1 of 3 people)

Drug effectiveness by age:

Levetiracetam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 66.0% - (2 of 3 people)
  • 10-19: 33.0% - (1 of 3 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 33.0% - (1 of 3 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • drooling
  • dysarthria
  • hyperammonaemia
  • insomnia
  • muscular weakness
6 - 12 months:
  • thrombocytopenia
  • carnitine abnormal
  • erythromelalgia
  • hyperactivity
  • insomnia
1 - 2 years:
  • leukocytosis
  • carnitine abnormal
5 - 10 years:
  • erythromelalgia
  • hyperactivity
  • insomnia
not specified:
  • convulsion
  • pyrexia
  • cognitive disorder
  • ear infection
  • nephrolithiasis
  • gastrooesophageal reflux disease
  • stomatitis
  • vomiting
  • weight decreased
  • constipation

Most common drug interactions by gender *:

female:
  • convulsion
  • cognitive disorder
  • ear infection
  • nephrolithiasis
  • stomatitis
  • hypotension
  • pyrexia
  • diarrhoea
  • anticonvulsant drug level decreased
  • death
male:
  • dehydration
  • mood altered
  • convulsion
  • hallucination, visual
  • irregular sleep phase
  • lethargy
  • psychomotor hyperactivity
  • sedation
  • somnolence
  • coordination abnormal

Most common drug interactions by age *:

0-1:
  • drug ineffective
  • hyperammonaemia
  • insomnia
  • somnolence
2-9:
  • cognitive disorder
  • convulsion
  • ear infection
  • nephrolithiasis
  • stomatitis
  • dehydration
  • lethargy
  • coordination abnormal
  • rash
  • right ventricular hypertrophy
10-19:
  • convulsion
  • mood altered
  • anticonvulsant drug level decreased
  • hallucination, visual
  • irregular sleep phase
  • psychomotor hyperactivity
  • sedation
  • death
  • agitation
  • akathisia
20-29:
  • diarrhoea
  • diplopia
  • headache
  • hypocalcaemia
  • hyponatraemia
  • hypotension
  • hypothyroidism
  • lymphopenia
  • neutropenia
  • photopsia
30-39:
  • circadian rhythm sleep disorder
  • convulsion
40-49:
  • hypotension
  • tumour flare
  • abasia
  • anaemia postoperative
  • blood creatine phosphokinase increased
  • central nervous system lesion
  • convulsion
  • drug withdrawal syndrome
  • gamma-glutamyltransferase increased
  • hypoaesthesia
50-59:
  • asthma
  • bronchospasm
  • anaemia
  • blood chloride decreased
  • blood glucose increased
  • blood sodium decreased
  • cardio-respiratory arrest
  • cerebral haematoma
  • cerebral haemorrhage
  • coma
60+:
  • nausea
  • asthenia
  • cough
  • death
  • fatigue
  • gastrooesophageal reflux disease
  • infection
  • infusion site haematoma
  • infusion site haemorrhage
  • pyrexia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Levetiracetam (levetiracetam) is often used to treat epilepsy. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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