Review: taking Lexapro and Savella together


Summary

Drug interactions are reported among people who take Lexapro and Savella together. This review analyzes the effectiveness and drug interactions between Lexapro and Savella. It is created by eHealthMe based on reports of 70 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 39,066 users)

Savella

Savella has active ingredients of milnacipran hydrochloride. It is often used in fibromyalgia. (latest outcomes from Savella 3,324 users)

On Jul, 29, 2016

70 people who take Lexapro, Savella are studied.


Number of reports submitted per year:

Lexapro and Savella drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Savella:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lexapro:
  • female: 22.0% - (2 of 9 people)
  • male: 0.0% - (0 of 1 people)
Savella:
  • female: 25.0% - (2 of 8 people)
  • male: 0.0% - (0 of 0 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 40.0% - (2 of 5 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 0.0% - (0 of 0 people)
Savella:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • hyperhidrosis
  • feeling abnormal
  • palpitations
  • tremor
  • abdominal pain
  • nausea
  • asthenia
  • multiple drug overdose intentional
  • suicidal ideation
  • suicide attempt
1 - 6 months:
  • depression
  • panic attack
  • aggression
  • apathy
  • blepharospasm
  • blood glucose decreased
  • derealisation
  • drug withdrawal syndrome
  • feeling abnormal
  • hyperreflexia
1 - 2 years:
  • anxiety aggravated
2 - 5 years:
  • aggression
  • apathy
  • blepharospasm
  • blood glucose decreased
  • depression
  • derealisation
  • drug withdrawal syndrome
  • feeling abnormal
  • hyperreflexia
  • mania
not specified:
  • fatigue
  • nausea
  • dyspnoea
  • hyperhidrosis
  • ileus
  • decreased appetite
  • activities of daily living impaired
  • anxiety
  • diarrhoea
  • impaired driving ability

Most common drug interactions by gender *:

female:
  • hyperhidrosis
  • dyspnoea
  • ileus
  • palpitations
  • fatigue
  • nausea
  • abdominal pain
  • tremor
  • asthenia
  • leukocytosis
male:
  • aggression
  • apathy
  • blepharospasm
  • blood glucose decreased
  • depression
  • derealisation
  • drug withdrawal syndrome
  • feeling abnormal
  • hyperreflexia
  • mania

Most common drug interactions by age *:

20-29:
  • aggression
  • apathy
  • blepharospasm
  • blood glucose decreased
  • depression
  • derealisation
  • drug withdrawal syndrome
  • feeling abnormal
  • hyperreflexia
  • mania
30-39:
  • decreased appetite
  • diarrhoea
  • hyperkalaemia
  • nausea
  • adverse drug reaction
  • extrapyramidal disorder
  • anger
  • depression
  • disorientation
  • disturbance in attention
40-49:
  • dyspnoea
  • palpitations
  • feeling abnormal
  • tremor
  • anaphylactic reaction
  • asthenia
  • blood pressure increased
  • dizziness
  • headache
  • heart rate increased
50-59:
  • hyperhidrosis
  • ileus
  • nausea
  • abdominal pain
  • fatigue
  • leukocytosis
  • renal failure acute
  • multiple drug overdose intentional
  • suicide attempt
  • activities of daily living impaired
60+:
  • infusion related reaction
  • local swelling
  • oedema peripheral
  • swelling face
  • swollen tongue
  • hot flush
  • asthenia
  • cough
  • depression
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Savella (milnacipran hydrochloride) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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