Review: taking Lexapro and Seroquel xr together


Summary

Drug interactions are reported among people who take Lexapro and Seroquel xr together. This review analyzes the effectiveness and drug interactions between Lexapro and Seroquel xr. It is created by eHealthMe based on reports of 4,709 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 43,172 users)

Seroquel Xr

Seroquel xr has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel xr 9,148 users)

On Aug, 21, 2016

4,709 people who take Lexapro, Seroquel Xr are studied.


Number of reports submitted per year:

Lexapro and Seroquel xr drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 16.0% - (3 of 18 people)
  • 1 - 6 months: 28.0% - (11 of 38 people)
  • 6 - 12 months: 38.0% - (10 of 26 people)
  • 1 - 2 years: 23.0% - (7 of 30 people)
  • 2 - 5 years: 32.0% - (12 of 37 people)
  • 5 - 10 years: 50.0% - (9 of 18 people)
  • 10+ years: 18.0% - (2 of 11 people)
  • not specified: 0.0% - (0 of 4 people)
Seroquel Xr:
  • < 1 month: 15.0% - (4 of 26 people)
  • 1 - 6 months: 37.0% - (13 of 35 people)
  • 6 - 12 months: 45.0% - (9 of 20 people)
  • 1 - 2 years: 45.0% - (17 of 37 people)
  • 2 - 5 years: 60.0% - (20 of 33 people)
  • 5 - 10 years: 66.0% - (14 of 21 people)
  • 10+ years: 40.0% - (2 of 5 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Lexapro:
  • female: 33.0% - (40 of 118 people)
  • male: 21.0% - (14 of 64 people)
Seroquel Xr:
  • female: 46.0% - (54 of 117 people)
  • male: 41.0% - (26 of 62 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 18.0% - (3 of 16 people)
  • 20-29: 31.0% - (13 of 41 people)
  • 30-39: 34.0% - (13 of 38 people)
  • 40-49: 30.0% - (12 of 39 people)
  • 50-59: 34.0% - (10 of 29 people)
  • 60+: 16.0% - (3 of 18 people)
Seroquel Xr:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 28.0% - (4 of 14 people)
  • 20-29: 33.0% - (14 of 42 people)
  • 30-39: 52.0% - (20 of 38 people)
  • 40-49: 51.0% - (19 of 37 people)
  • 50-59: 64.0% - (18 of 28 people)
  • 60+: 21.0% - (4 of 19 people)

Most common drug interactions over time *:

< 1 month:
  • type 2 diabetes mellitus
  • somnolence
  • suicidal ideation
  • blood cholesterol increased
  • diabetes mellitus
  • suicide attempt
  • depression
  • agitation
  • blood triglycerides increased
  • confusional state
1 - 6 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • diabetes mellitus inadequate control
  • insomnia
  • chest pain
  • neuropathy peripheral
  • blood cholesterol increased
  • obesity
  • type 1 diabetes mellitus
  • depression
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • weight increased
  • diabetes mellitus inadequate control
  • thrombosis
  • chest pain
  • neuropathy peripheral
  • diabetic ketoacidosis
  • abdominal pain upper
1 - 2 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • hyperglycaemia
  • obesity
  • blood cholesterol increased
  • diabetes mellitus inadequate control
  • pancreatitis
  • back pain
  • neuropathy peripheral
  • suicidal ideation
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • pancreatitis
  • diabetes mellitus inadequate control
  • blood cholesterol increased
  • obesity
  • diabetic neuropathy
  • suicidal ideation
  • neuropathy peripheral
  • weight increased
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • neuropathy peripheral
  • hyperlipidaemia
  • diabetes mellitus inadequate control
  • hyperglycaemia
  • suicidal ideation
  • blood triglycerides increased
10+ years:
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • diabetes mellitus
  • dizziness
  • somnolence
  • asthenia
  • cholelithiasis
  • dehydration
  • urinary tract infection
  • diabetes mellitus inadequate control
not specified:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • weight increased
  • insomnia
  • depression
  • anxiety
  • diabetes mellitus inadequate control
  • suicidal ideation
  • pancreatitis

Most common drug interactions by gender *:

female:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • diabetes mellitus inadequate control
  • weight increased
  • obesity
  • insomnia
  • pancreatitis
  • hyperglycaemia
  • depression
male:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • anxiety
  • suicidal ideation
  • blood cholesterol increased
  • depression
  • weight increased
  • insomnia
  • neuropathy peripheral
  • diabetic neuropathy

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • foetal exposure during pregnancy
  • pancreatitis
  • premature baby
  • suicidal ideation
  • depression
  • drug withdrawal syndrome neonatal
  • escherichia sepsis
  • extrapyramidal disorder
  • hypernatraemia
2-9:
  • tic
  • jaw disorder
  • throat irritation
  • tremor
  • diarrhoea
  • suicidal ideation
  • abnormal behaviour
  • mood swings
  • anger
  • anxiety
10-19:
  • diabetes mellitus
  • weight increased
  • diabetic ketoacidosis
  • bipolar disorder
  • dystonia
  • mania
  • suicidal ideation
  • type 2 diabetes mellitus
  • abnormal behaviour
  • accidental overdose
20-29:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • insomnia
  • back pain
  • overdose
  • suicidal ideation
  • abdominal pain
  • headache
  • abdominal pain upper
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • diabetes mellitus inadequate control
  • blood cholesterol increased
  • weight increased
  • obesity
  • diabetic neuropathy
  • pancreatitis
  • hyperglycaemia
  • diabetic ketoacidosis
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • neuropathy peripheral
  • diabetes mellitus inadequate control
  • hyperlipidaemia
  • obesity
  • pancreatitis
  • weight increased
  • arthralgia
50-59:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • hyperglycaemia
  • obesity
  • weight increased
  • diabetes mellitus inadequate control
  • somnolence
  • back pain
  • insomnia
60+:
  • anxiety
  • depression
  • diabetes mellitus
  • fall
  • insomnia
  • type 2 diabetes mellitus
  • confusional state
  • suicidal ideation
  • headache
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Seroquel xr (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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