Review: taking Lexapro and Topamax together


Summary

Drug interactions are reported among people who take Lexapro and Topamax together. This review analyzes the effectiveness and drug interactions between Lexapro and Topamax. It is created by eHealthMe based on reports of 2,125 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 52,596 users)

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 34,483 users)

On Sep, 16, 2016

2,125 people who take Lexapro, Topamax are studied.


Number of reports submitted per year:

Lexapro and Topamax drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 28.0% - (2 of 7 people)
  • 1 - 6 months: 16.0% - (3 of 18 people)
  • 6 - 12 months: 25.0% - (3 of 12 people)
  • 1 - 2 years: 33.0% - (5 of 15 people)
  • 2 - 5 years: 47.0% - (16 of 34 people)
  • 5 - 10 years: 70.0% - (12 of 17 people)
  • 10+ years: 36.0% - (4 of 11 people)
  • not specified: 0.0% - (0 of 1 people)
Topamax:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 47.0% - (11 of 23 people)
  • 6 - 12 months: 33.0% - (5 of 15 people)
  • 1 - 2 years: 28.0% - (4 of 14 people)
  • 2 - 5 years: 48.0% - (13 of 27 people)
  • 5 - 10 years: 68.0% - (11 of 16 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Lexapro:
  • female: 42.0% - (43 of 101 people)
  • male: 14.0% - (2 of 14 people)
Topamax:
  • female: 47.0% - (47 of 98 people)
  • male: 33.0% - (4 of 12 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 36.0% - (8 of 22 people)
  • 30-39: 31.0% - (10 of 32 people)
  • 40-49: 37.0% - (14 of 37 people)
  • 50-59: 64.0% - (11 of 17 people)
  • 60+: 50.0% - (2 of 4 people)
Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 60.0% - (3 of 5 people)
  • 20-29: 57.0% - (11 of 19 people)
  • 30-39: 58.0% - (17 of 29 people)
  • 40-49: 37.0% - (14 of 37 people)
  • 50-59: 37.0% - (6 of 16 people)
  • 60+: 0.0% - (0 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • hepatitis cholestatic
  • overdose
  • grand mal convulsion
  • leukopenia
  • somnolence
  • depression
  • fatigue
  • nausea
  • suicidal ideation
  • weight increased
1 - 6 months:
  • depression
  • vomiting
  • headache
  • suicidal ideation
  • grand mal convulsion
  • leukopenia
  • nausea
  • tremor
  • dizziness
  • overdose
6 - 12 months:
  • emotional disorder
  • suicide attempt
  • drug toxicity
  • growth retardation
  • hypospadias
  • overdose
  • agitation
  • depression
  • sleepiness
  • somnolence
1 - 2 years:
  • anxiety
  • convulsion
  • pain
  • depression
  • obesity
  • sleep apnoea syndrome
  • type 2 diabetes mellitus
  • chest pain
  • vomiting
  • acute respiratory failure
2 - 5 years:
  • anxiety
  • vitamin d deficiency
  • depression
  • dizziness
  • headache
  • basilar migraine
  • deep vein thrombosis
  • head injury
  • occipital neuralgia
  • pulmonary embolism
5 - 10 years:
  • emotional distress
  • premature delivery
  • anxiety
  • chorioamnionitis
  • maternal exposure during pregnancy
  • bipolar disorder
  • choking
  • stress
  • attention deficit/hyperactivity disorder
  • bronchopulmonary dysplasia
10+ years:
  • akathisia
  • breast cancer female
  • enuresis
  • impairment of speech
  • memory impairment
  • short-term memory loss
  • teeth grinding and clenching
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • folliculitis
  • sleepy
not specified:
  • pain
  • nausea
  • depression
  • anxiety
  • headache
  • fatigue
  • dizziness
  • diabetes mellitus
  • weight increased
  • drug ineffective

Most common drug interactions by gender *:

female:
  • depression
  • pain
  • nausea
  • anxiety
  • dizziness
  • headache
  • fatigue
  • type 2 diabetes mellitus
  • vomiting
  • drug ineffective
male:
  • diabetes mellitus
  • pain
  • anxiety
  • suicidal ideation
  • nausea
  • convulsion
  • depression
  • drug ineffective
  • headache
  • type 2 diabetes mellitus

Most common drug interactions by age *:

0-1:
  • feeding disorder neonatal
  • drug exposure during pregnancy
  • drug exposure via breast milk
  • sedation
  • abasia
  • abdominal pain
  • abscess
  • amnesia
  • anaemia
  • atrial septal defect
2-9:
  • seizure
  • paresis
  • axillary mass
  • bone pain
  • breast cancer
  • drug exposure via breast milk
  • feeding disorder neonatal
  • irritability
  • medical device complication
  • metastases to lymph nodes
10-19:
  • suicide attempt
  • depression
  • weight increased
  • convulsion
  • anxiety
  • dizziness
  • insomnia
  • mania
  • renal failure
  • bradycardia
20-29:
  • pain
  • abdominal pain
  • dyspnoea
  • headache
  • abdominal pain upper
  • anxiety
  • weight increased
  • nausea
  • urinary tract infection
  • diabetes mellitus
30-39:
  • depression
  • pain
  • anxiety
  • nausea
  • convulsion
  • headache
  • diabetes mellitus
  • type 2 diabetes mellitus
  • fatigue
  • pulmonary embolism
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • pain
  • depression
  • nausea
  • back pain
  • anxiety
  • headache
  • dizziness
  • weight increased
50-59:
  • depression
  • nausea
  • fatigue
  • anxiety
  • drug ineffective
  • headache
  • pain
  • diabetes mellitus
  • arthralgia
  • weight increased
60+:
  • anxiety
  • nausea
  • pain
  • fatigue
  • dizziness
  • dyspnoea
  • asthenia
  • drug ineffective
  • headache
  • oedema peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Topamax (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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