Review: taking Lexapro and Topamax together


Summary

Drug interactions are reported among people who take Lexapro and Topamax together. This review analyzes the effectiveness and drug interactions between Lexapro and Topamax. It is created by eHealthMe based on reports of 1,471 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 39,072 users)

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,310 users)

On Jul, 20, 2016

1,471 people who take Lexapro, Topamax are studied.


Number of reports submitted per year:

Lexapro and Topamax drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 15.0% - (3 of 19 people)
  • 6 - 12 months: 30.0% - (4 of 13 people)
  • 1 - 2 years: 29.0% - (5 of 17 people)
  • 2 - 5 years: 42.0% - (18 of 42 people)
  • 5 - 10 years: 73.0% - (17 of 23 people)
  • 10+ years: 46.0% - (6 of 13 people)
  • not specified: 0.0% - (0 of 3 people)
Topamax:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 38.0% - (12 of 31 people)
  • 6 - 12 months: 35.0% - (6 of 17 people)
  • 1 - 2 years: 26.0% - (4 of 15 people)
  • 2 - 5 years: 43.0% - (13 of 30 people)
  • 5 - 10 years: 72.0% - (16 of 22 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 33.0% - (1 of 3 people)

Drug effectiveness by gender:

Lexapro:
  • female: 42.0% - (52 of 122 people)
  • male: 18.0% - (3 of 16 people)
Topamax:
  • female: 45.0% - (54 of 118 people)
  • male: 28.0% - (4 of 14 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 34.0% - (8 of 23 people)
  • 30-39: 30.0% - (12 of 40 people)
  • 40-49: 40.0% - (18 of 45 people)
  • 50-59: 63.0% - (14 of 22 people)
  • 60+: 60.0% - (3 of 5 people)
Topamax:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (4 of 6 people)
  • 20-29: 60.0% - (12 of 20 people)
  • 30-39: 48.0% - (17 of 35 people)
  • 40-49: 35.0% - (16 of 45 people)
  • 50-59: 42.0% - (9 of 21 people)
  • 60+: 0.0% - (0 of 5 people)

Most common drug interactions over time *:

< 1 month:
  • hepatitis cholestatic
  • grand mal convulsion
  • leukopenia
  • overdose
  • fatigue
  • nausea
  • somnolence
  • fall
  • headache
  • hyperammonaemia
1 - 6 months:
  • depression
  • suicidal ideation
  • grand mal convulsion
  • leukopenia
  • nausea
  • dizziness
  • overdose
  • tremor
  • occipital neuralgia
  • type 2 diabetes mellitus
6 - 12 months:
  • drug toxicity
  • overdose
  • agitation
  • growth retardation
  • hypospadias
  • sleepiness
  • somnolence
  • suicide attempt
  • thrombocytopenia
  • aggression
1 - 2 years:
  • convulsion
  • obesity
  • sleep apnoea syndrome
  • type 2 diabetes mellitus
  • anxiety
  • chest pain
  • depression
  • acute respiratory failure
  • fecal incontinence
  • nausea
2 - 5 years:
  • anxiety
  • depression
  • dizziness
  • basilar migraine
  • deep vein thrombosis
  • head injury
  • occipital neuralgia
  • fatigue
  • pulmonary embolism
  • weight gain - unintentional
5 - 10 years:
  • emotional distress
  • chorioamnionitis
  • maternal exposure during pregnancy
  • premature delivery
  • choking
  • attention deficit/hyperactivity disorder
  • bipolar disorder
  • bronchopulmonary dysplasia
  • cleft lip and palate
  • congenital central nervous system anomaly
10+ years:
  • akathisia
  • breast cancer female
  • enuresis
  • impairment of speech
  • memory impairment
  • short-term memory loss
  • teeth grinding and clenching
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • folliculitis
  • sleepy
not specified:
  • diabetes mellitus
  • pain
  • nausea
  • depression
  • dizziness
  • type 2 diabetes mellitus
  • anxiety
  • weight increased
  • headache
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • depression
  • diabetes mellitus
  • type 2 diabetes mellitus
  • dizziness
  • anxiety
  • headache
  • weight increased
  • back pain
male:
  • diabetes mellitus
  • suicidal ideation
  • convulsion
  • anxiety
  • depression
  • type 2 diabetes mellitus
  • overdose
  • nausea
  • fatigue
  • headache

Most common drug interactions by age *:

0-1:
  • drug exposure during pregnancy
  • drug exposure via breast milk
  • feeding disorder neonatal
  • abdominal pain
  • abscess
  • anaemia
  • clostridium difficile colitis
  • colitis ulcerative
  • constipation
  • dehydration
2-9:
  • drug exposure via breast milk
  • feeding disorder neonatal
  • sedation
10-19:
  • suicide attempt
  • depression
  • convulsion
  • anxiety
  • bradycardia
  • affective disorder
  • aggression
  • dizziness
  • drug dependence
  • drug rash with eosinophilia and systemic symptoms
20-29:
  • pain
  • abdominal pain
  • dyspnoea
  • headache
  • abdominal pain upper
  • diabetes mellitus
  • urinary tract infection
  • weight increased
  • nausea
  • dizziness
30-39:
  • depression
  • diabetes mellitus
  • type 2 diabetes mellitus
  • anxiety
  • convulsion
  • headache
  • nausea
  • pain
  • dyspnoea
  • pulmonary embolism
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • back pain
  • depression
  • pain
  • fall
  • neuropathy peripheral
  • nausea
  • weight increased
  • dizziness
50-59:
  • depression
  • nausea
  • diabetes mellitus
  • anxiety
  • weight increased
  • type 2 diabetes mellitus
  • back pain
  • fatigue
  • convulsion
  • suicidal ideation
60+:
  • pain
  • anxiety
  • nausea
  • asthenia
  • impaired healing
  • rib fracture
  • tooth disorder
  • oedema peripheral
  • rash
  • cardiac arrest

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Topamax (topiramate) is often used to treat migraine. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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