Review: taking Lexapro and Tramadol together


Summary

Drug interactions are reported among people who take Lexapro and Tramadol together. This review analyzes the effectiveness and drug interactions between Lexapro and Tramadol. It is created by eHealthMe based on reports of 1,817 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 44,435 users)

Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 52,446 users)

On Aug, 29, 2016

1,817 people who take Lexapro, Tramadol are studied.


Number of reports submitted per year:

Lexapro and Tramadol drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 28.0% - (2 of 7 people)
  • 1 - 6 months: 23.0% - (3 of 13 people)
  • 6 - 12 months: 61.0% - (8 of 13 people)
  • 1 - 2 years: 42.0% - (6 of 14 people)
  • 2 - 5 years: 64.0% - (11 of 17 people)
  • 5 - 10 years: 50.0% - (4 of 8 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Tramadol:
  • < 1 month: 22.0% - (4 of 18 people)
  • 1 - 6 months: 11.0% - (2 of 17 people)
  • 6 - 12 months: 50.0% - (4 of 8 people)
  • 1 - 2 years: 33.0% - (4 of 12 people)
  • 2 - 5 years: 40.0% - (6 of 15 people)
  • 5 - 10 years: 77.0% - (7 of 9 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lexapro:
  • female: 47.0% - (28 of 59 people)
  • male: 52.0% - (10 of 19 people)
Tramadol:
  • female: 29.0% - (18 of 61 people)
  • male: 47.0% - (10 of 21 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 36.0% - (4 of 11 people)
  • 30-39: 33.0% - (4 of 12 people)
  • 40-49: 64.0% - (16 of 25 people)
  • 50-59: 45.0% - (9 of 20 people)
  • 60+: 50.0% - (5 of 10 people)
Tramadol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 30.0% - (4 of 13 people)
  • 30-39: 18.0% - (2 of 11 people)
  • 40-49: 45.0% - (11 of 24 people)
  • 50-59: 26.0% - (6 of 23 people)
  • 60+: 45.0% - (5 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • diverticulitis
  • large intestine perforation
  • suicide attempt
  • intentional overdose
  • rhabdomyolysis
  • alanine aminotransferase increased
  • hypercreatininaemia
  • multiple drug overdose intentional
  • blood calcium decreased
  • confusional state
1 - 6 months:
  • diarrhoea
  • rhabdomyolysis
  • convulsion
  • depression
  • hypercreatininaemia
  • mental status changes
  • pain
  • fatigue
  • grand mal convulsion
  • suicide attempt
6 - 12 months:
  • suicidal ideation
  • ammonia increased
  • chest pain
  • depression
  • gastrooesophageal reflux disease
  • headache
  • nausea
  • overdose
  • pain in extremity
  • suicide attempt
1 - 2 years:
  • deep vein thrombosis
  • suicide attempt
  • depression
  • epistaxis
  • hypotension
  • sinus tachycardia
  • anal haemorrhage
  • anxiety
  • bursitis
  • chest discomfort
2 - 5 years:
  • basilar migraine
  • head injury
  • occipital neuralgia
  • depression
  • aggression
  • anxiety
  • loss of consciousness
  • nausea
  • suicide attempt
  • chest pain
5 - 10 years:
  • back pain
  • depression
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • nail growth abnormal
  • aggression
  • akathisia
  • confusional state
  • confusion
  • paranoia
  • ammonia increased
10+ years:
  • bone and joint pain
  • night sweats
  • depression
  • functional ovarian cysts
  • knee pain
  • middle insomnia
  • physiologic ovarian cysts
not specified:
  • pain
  • nausea
  • anxiety
  • fatigue
  • depression
  • diarrhoea
  • fall
  • dyspnoea
  • abdominal pain
  • anaemia

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • diarrhoea
  • fatigue
  • fall
  • dyspnoea
  • depression
  • abdominal pain
  • oedema peripheral
male:
  • depression
  • anxiety
  • pain
  • dizziness
  • nausea
  • fatigue
  • hypotension
  • anaemia
  • dyspnoea
  • pneumonia

Most common drug interactions by age *:

10-19:
  • accidental overdose
  • mania
  • suicide attempt
  • completed suicide
  • epistaxis
  • anal haemorrhage
  • cholecystitis chronic
  • depression
  • nasal congestion
  • scab
20-29:
  • serotonin syndrome
  • multiple drug overdose
  • pain
  • anxiety
  • depression
  • cholelithiasis
  • deep vein thrombosis
  • nausea
  • cholecystitis chronic
  • convulsion
30-39:
  • nausea
  • anxiety
  • diabetes mellitus
  • vomiting
  • pulmonary embolism
  • depression
  • back pain
  • weight increased
  • abdominal pain
  • dyspepsia
40-49:
  • nausea
  • headache
  • pain
  • anxiety
  • depression
  • abdominal pain
  • fatigue
  • back pain
  • vomiting
  • anaemia
50-59:
  • nausea
  • pain
  • anxiety
  • diarrhoea
  • fall
  • oedema peripheral
  • cough
  • bone disorder
  • abdominal pain
  • pyrexia
60+:
  • dyspnoea
  • fatigue
  • anxiety
  • pain
  • nausea
  • fall
  • asthenia
  • injury
  • diarrhoea
  • anaemia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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