Review: taking Lexapro and Zyrtec together


Summary

Drug interactions are reported among people who take Lexapro and Zyrtec together. This review analyzes the effectiveness and drug interactions between Lexapro and Zyrtec. It is created by eHealthMe based on reports of 1,544 people who take the same drugs from FDA and social media, and is updated regularly.

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Lexapro

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from Lexapro 52,596 users)

Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 46,713 users)

On Sep, 19, 2016

1,544 people who take Lexapro, Zyrtec are studied.


Number of reports submitted per year:

Lexapro and Zyrtec drug interactions.

Drug effectiveness over time:

Lexapro:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 46.0% - (7 of 15 people)
  • 6 - 12 months: 60.0% - (3 of 5 people)
  • 1 - 2 years: 66.0% - (6 of 9 people)
  • 2 - 5 years: 69.0% - (9 of 13 people)
  • 5 - 10 years: 53.0% - (8 of 15 people)
  • 10+ years: 28.0% - (2 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Zyrtec:
  • < 1 month: 33.0% - (3 of 9 people)
  • 1 - 6 months: 45.0% - (5 of 11 people)
  • 6 - 12 months: 33.0% - (2 of 6 people)
  • 1 - 2 years: 30.0% - (3 of 10 people)
  • 2 - 5 years: 50.0% - (11 of 22 people)
  • 5 - 10 years: 33.0% - (4 of 12 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lexapro:
  • female: 51.0% - (29 of 56 people)
  • male: 42.0% - (6 of 14 people)
Zyrtec:
  • female: 40.0% - (24 of 59 people)
  • male: 40.0% - (6 of 15 people)

Drug effectiveness by age:

Lexapro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 20.0% - (1 of 5 people)
  • 20-29: 76.0% - (10 of 13 people)
  • 30-39: 58.0% - (10 of 17 people)
  • 40-49: 33.0% - (6 of 18 people)
  • 50-59: 33.0% - (4 of 12 people)
  • 60+: 100.0% - (4 of 4 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 100.0% - (1 of 1 people)
  • 10-19: 16.0% - (1 of 6 people)
  • 20-29: 53.0% - (8 of 15 people)
  • 30-39: 21.0% - (4 of 19 people)
  • 40-49: 50.0% - (8 of 16 people)
  • 50-59: 53.0% - (7 of 13 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • fall
  • anaphylactic shock
  • confusional state
  • pruritus
  • amnesia
  • asthenia
  • bradycardia
  • coma scale abnormal
  • dermatitis allergic
1 - 6 months:
  • anxiety
  • depression
  • diarrhoea
  • hepatitis
  • pancreatitis
  • renal failure acute
  • suicidal ideation
  • anaphylactic shock
  • bipolar disorder
  • breath odour
6 - 12 months:
  • atelectasis
  • mental disorder
  • pain
  • pleural effusion
  • pulmonary embolism
  • abdominal pain upper
  • back pain
  • cholecystitis acute
  • cholecystitis chronic
  • cholelithiasis
1 - 2 years:
  • depression
  • anxiety
  • dissociation
  • drug screen positive
  • hallucination, visual
  • insomnia
  • loss of employment
  • pain - joints
  • pain - muscles
  • pneumonitis
2 - 5 years:
  • eyes - sensitive to light
  • headache - mixed tension migraine
  • lightheadedness - dizzy
  • muscle cramps aggravated
  • headache
  • depression
  • pain
  • anxiety
  • blood pressure ambulatory increased
  • injury
5 - 10 years:
  • choking
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • weight gain
  • depression
  • aggression
  • anxiety disorder
  • autism spectrum disorder
  • cholecystitis chronic
  • cholelithiasis
  • dermatitis
10+ years:
  • perianal fungal infection
  • teeth grinding and clenching
  • bone and joint pain
  • breast cancer female
  • constipation
  • eczema
  • hyperthyroidism
  • irritability
  • night sweats
  • oral lichen planus
not specified:
  • pain
  • nausea
  • anxiety
  • fall
  • depression
  • constipation
  • back pain
  • arthralgia
  • fatigue
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • fall
  • depression
  • constipation
  • arthralgia
  • pain in extremity
  • fatigue
  • back pain
male:
  • nausea
  • pain
  • dyspnoea
  • rash
  • arthralgia
  • depression
  • injury
  • anxiety
  • fatigue
  • pneumonia

Most common drug interactions by age *:

0-1:
  • convulsion neonatal
  • drug exposure during pregnancy
  • drug withdrawal syndrome
  • flushing
  • gallbladder pain
  • hyperexplexia
  • hyperreflexia
  • nausea
  • subarachnoid haemorrhage
  • subdural haemorrhage
2-9:
  • anxiety
  • allergic granulomatous angiitis
  • gastrooesophageal reflux disease
  • lung neoplasm
  • aggression
  • anxiety disorder
  • autism spectrum disorder
  • depression
  • hyperactivity
  • oppositional defiant disorder
10-19:
  • nausea
  • weight increased
  • anxiety
  • fatigue
  • pyrexia
  • eye swelling
  • cholecystitis chronic
  • decreased appetite
  • suicidal ideation
  • vomiting
20-29:
  • nausea
  • headache
  • deep vein thrombosis
  • cholecystitis chronic
  • dyspnoea
  • pain
  • anxiety
  • dizziness
  • injury
  • abdominal pain
30-39:
  • nausea
  • anxiety
  • pain
  • constipation
  • headache
  • dizziness
  • dyspnoea
  • fatigue
  • depression
  • abdominal pain
40-49:
  • pain
  • nausea
  • fall
  • back pain
  • gastrooesophageal reflux disease
  • vomiting
  • diarrhoea
  • depression
  • abdominal pain
  • anxiety
50-59:
  • pain
  • arthralgia
  • anxiety
  • depression
  • fatigue
  • nausea
  • neuropathy peripheral
  • osteonecrosis of jaw
  • hypoaesthesia
  • chronic obstructive pulmonary disease
60+:
  • pain
  • anxiety
  • nausea
  • fall
  • constipation
  • arthralgia
  • cardiac failure congestive
  • diarrhoea
  • anaemia
  • urinary tract infection

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lexapro (escitalopram oxalate) is often used to treat depression. Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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