Review: taking Lisinopril and Benadryl together


Summary

Drug interactions are reported among people who take Lisinopril and Benadryl together. This review analyzes the effectiveness and drug interactions between Lisinopril and Benadryl. It is created by eHealthMe based on reports of 2,437 people who take the same drugs from FDA and social media, and is updated regularly.

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Lisinopril

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. (latest outcomes from Lisinopril 115,032 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 32,636 users)

On Aug, 24, 2016

2,437 people who take Lisinopril, Benadryl are studied.


Number of reports submitted per year:

Lisinopril and Benadryl drug interactions.

Drug effectiveness over time:

Lisinopril:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 37.0% - (3 of 8 people)
  • 6 - 12 months: 50.0% - (3 of 6 people)
  • 1 - 2 years: 70.0% - (7 of 10 people)
  • 2 - 5 years: 41.0% - (5 of 12 people)
  • 5 - 10 years: 66.0% - (4 of 6 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Benadryl:
  • < 1 month: 50.0% - (3 of 6 people)
  • 1 - 6 months: 30.0% - (3 of 10 people)
  • 6 - 12 months: 28.0% - (2 of 7 people)
  • 1 - 2 years: 33.0% - (2 of 6 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 66.0% - (6 of 9 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Lisinopril:
  • female: 51.0% - (14 of 27 people)
  • male: 43.0% - (10 of 23 people)
Benadryl:
  • female: 40.0% - (11 of 27 people)
  • male: 41.0% - (10 of 24 people)

Drug effectiveness by age:

Lisinopril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 20.0% - (1 of 5 people)
  • 40-49: 54.0% - (6 of 11 people)
  • 50-59: 56.0% - (9 of 16 people)
  • 60+: 40.0% - (6 of 15 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 33.0% - (1 of 3 people)
  • 30-39: 0.0% - (0 of 5 people)
  • 40-49: 33.0% - (4 of 12 people)
  • 50-59: 46.0% - (7 of 15 people)
  • 60+: 56.0% - (9 of 16 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • dehydration
  • hypotension
  • pain
  • sepsis
  • anxiety
  • mucosal inflammation
  • fear
  • injury
  • bk virus infection
1 - 6 months:
  • cold-stimulus headache
  • mucosal inflammation
  • hives
  • chest pressure sensation
  • dehydration
  • enteritis
  • headache
  • muscle spasms
  • neck pain
  • neck swelling
6 - 12 months:
  • appendicitis
  • heart rate increased
  • angioedema
  • constipation aggravated
  • coronary artery disease
  • gastrointestinal oedema
  • gynaecomastia
  • haemorrhagic stroke
  • ischaemic stroke
  • lacrimation increased
1 - 2 years:
  • hyponatraemia
  • dysgeusia
  • hair loss
  • hearing loss
  • heart pounding or racing
  • nausea
  • palpitations
  • anxiety
  • appendicitis
  • cellulitis
2 - 5 years:
  • chest pain
  • headache
  • anaemia
  • arthralgia
  • coma
  • heart pounding or racing
  • multi-organ failure
  • palpitations
  • back pain
  • cold-stimulus headache
5 - 10 years:
  • dehydration
  • diarrhoea
  • febrile neutropenia
  • gastrointestinal haemorrhage
  • hyponatraemia
  • blood sodium decreased
  • haematemesis
  • hypotension
  • anaemia
  • arrhythmia
10+ years:
  • dysgeusia
  • hair loss
  • hearing loss
  • drug hypersensitivity
  • cerebrovascular accident
  • chest pain
  • dizziness
  • platelet count decreased
  • wheezing
  • haemorrhage
not specified:
  • nausea
  • pain
  • dyspnoea
  • fatigue
  • anxiety
  • anaemia
  • diarrhoea
  • vomiting
  • dizziness
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • diarrhoea
  • fatigue
  • vomiting
  • dyspnoea
  • anaemia
  • dizziness
  • arthralgia
male:
  • dyspnoea
  • fatigue
  • pain
  • nausea
  • hypotension
  • anaemia
  • arthralgia
  • pneumonia
  • anxiety
  • dizziness

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • nausea
  • asthenia
  • blister
  • blood pressure increased
  • body temperature increased
  • catheter site pain
  • chapped lips
  • chills
  • diarrhoea
  • dry skin
10-19:
  • postoperative ileus
  • crohn's disease
  • hypotension
  • sepsis
  • abdominal pain lower
  • activated partial thromboplastin time prolonged
  • aspergillosis
  • back pain
  • bradycardia
  • capillary leak syndrome
20-29:
  • cardiac failure congestive
  • bronchitis
  • cholecystitis
  • influenza like illness
  • insomnia
  • sinusitis
  • urinary tract infection
  • nausea
  • atrial fibrillation
  • back pain
30-39:
  • dyspnoea
  • chest pain
  • nausea
  • diabetes mellitus
  • vomiting
  • pain
  • type 2 diabetes mellitus
  • diabetes mellitus inadequate control
  • suicide attempt
  • appendicitis
40-49:
  • pain
  • anxiety
  • diarrhoea
  • nausea
  • emotional distress
  • hypertension
  • anaemia
  • gastrooesophageal reflux disease
  • dyspnoea
  • fatigue
50-59:
  • pain
  • nausea
  • anxiety
  • fatigue
  • osteoarthritis
  • vomiting
  • depression
  • anaemia
  • arthralgia
  • renal failure
60+:
  • dyspnoea
  • nausea
  • pain
  • anaemia
  • diarrhoea
  • fatigue
  • dizziness
  • hypotension
  • renal failure
  • anxiety

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lisinopril (lisinopril) is often used to treat high blood pressure. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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