Review: taking Lithium carbonate and Benadryl together


Summary

Drug interactions are reported among people who take Lithium carbonate and Benadryl together. This review analyzes the effectiveness and drug interactions between Lithium carbonate and Benadryl. It is created by eHealthMe based on reports of 255 people who take the same drugs from FDA and social media, and is updated regularly.

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Lithium Carbonate

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. (latest outcomes from Lithium carbonate 16,506 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 33,627 users)

On Aug, 26, 2016

255 people who take Lithium Carbonate, Benadryl are studied.


Number of reports submitted per year:

Lithium carbonate and Benadryl drug interactions.

Drug effectiveness over time:

Lithium Carbonate:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 20.0% - (1 of 5 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lithium Carbonate:
  • female: 27.0% - (3 of 11 people)
  • male: 83.0% - (5 of 6 people)
Benadryl:
  • female: 25.0% - (2 of 8 people)
  • male: 25.0% - (1 of 4 people)

Drug effectiveness by age:

Lithium Carbonate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 40.0% - (2 of 5 people)
  • 30-39: 33.0% - (2 of 6 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 100.0% - (1 of 1 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • tremor
  • muscle twitching
  • diarrhoea
  • drug-induced tremor
  • neutropenia
  • numbness and tingling
  • numbness in hands or feet
  • pain exacerbated
  • sleep
  • ageusia
1 - 6 months:
  • injury
  • pain
  • bipolar disorder
  • cholelithiasis
  • anxiety
  • emotional distress
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • general physical health deterioration
  • migraine
  • nausea
6 - 12 months:
  • death
1 - 2 years:
  • blister
  • insomnia
  • restless leg syndrome
  • restlessness
2 - 5 years:
  • drug ineffective
  • blister
  • insomnia
  • restless leg syndrome
  • restlessness
  • sinus bradycardia
5 - 10 years:
  • short-term memory loss
  • sweating - excessive
  • weight gain - unintentional
  • chest wall pain
  • drug level above therapeutic
  • gait disturbance
  • muscle strain
  • blood triglycerides increased
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • high blood sugar
10+ years:
  • drug-induced tremor
  • muscle twitching
  • numbness and tingling
  • numbness in hands or feet
  • pain exacerbated
  • muscle cramps
  • therapeutic agent toxicity
not specified:
  • weight increased
  • diabetes mellitus
  • type 2 diabetes mellitus
  • dizziness
  • suicidal ideation
  • insomnia
  • tremor
  • depression
  • dyspnoea
  • fatigue

Most common drug interactions by gender *:

female:
  • tremor
  • diabetes mellitus
  • weight increased
  • suicidal ideation
  • dyspnoea
  • depression
  • anxiety
  • dizziness
  • agitation
  • anger
male:
  • type 2 diabetes mellitus
  • weight increased
  • insomnia
  • diabetes mellitus
  • dizziness
  • fatigue
  • bipolar disorder
  • neuroleptic malignant syndrome
  • pancreatitis
  • aggression

Most common drug interactions by age *:

0-1:
  • balance disorder
  • bradycardia
  • cholecystitis chronic
  • convulsion
  • diabetic complication
  • dyspnoea
  • hyponatraemia
  • hypotension
  • nervous system disorder
  • orthopnoea
2-9:
  • adverse reaction
  • cardiac arrest
  • crying
  • impulsive behaviour
  • retching
  • suicidal ideation
  • asthma aggravated
  • blood calcium decreased
  • hypocalcaemia
  • sleep
10-19:
  • suicidal ideation
  • diabetes mellitus
  • akathisia
  • bipolar disorder
  • decreased appetite
  • depression
  • diarrhoea
  • excoriation
  • feeling guilty
  • influenza like illness
20-29:
  • diabetes mellitus
  • diabetic ketoacidosis
  • insomnia
  • nausea
  • hyperglycaemia
  • pancreatitis
  • gastrooesophageal reflux disease
  • abdominal pain
  • abdominal pain upper
  • coma
30-39:
  • vomiting
  • dyspnoea
  • diabetes mellitus
  • sedation
  • drug dependence
  • hypertension
  • palpitations
  • weight increased
  • agitation
  • anger
40-49:
  • dizziness
  • neuroleptic malignant syndrome
  • weight increased
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • loss of consciousness
  • somnolence
  • suicidal ideation
  • tremor
  • cerebrovascular accident
50-59:
  • type 2 diabetes mellitus
  • weight increased
  • fatigue
  • paraesthesia
  • insomnia
  • dizziness
  • nephropathy
  • anxiety
  • drug dependence
  • drug withdrawal syndrome
60+:
  • agitation
  • dyspnoea
  • mental status changes
  • syncope
  • acute myeloid leukaemia
  • abdominal pain
  • abdominal pain upper
  • aggression
  • anaemia
  • anorexia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lithium carbonate (lithium carbonate) is often used to treat bipolar disorder. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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