Review: taking Lithium carbonate and Lamictal together


Summary

Drug interactions are reported among people who take Lithium carbonate and Lamictal together. This review analyzes the effectiveness and drug interactions between Lithium carbonate and Lamictal. It is created by eHealthMe based on reports of 2,027 people who take the same drugs from FDA and social media, and is updated regularly.

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Lithium Carbonate

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. (latest outcomes from Lithium carbonate 16,506 users)

Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 45,312 users)

On Aug, 28, 2016

2,027 people who take Lithium Carbonate, Lamictal are studied.


Number of reports submitted per year:

Lithium carbonate and Lamictal drug interactions.

Drug effectiveness over time:

Lithium Carbonate:
  • < 1 month: 42.0% - (6 of 14 people)
  • 1 - 6 months: 37.0% - (13 of 35 people)
  • 6 - 12 months: 37.0% - (11 of 29 people)
  • 1 - 2 years: 41.0% - (12 of 29 people)
  • 2 - 5 years: 54.0% - (31 of 57 people)
  • 5 - 10 years: 52.0% - (23 of 44 people)
  • 10+ years: 66.0% - (34 of 51 people)
  • not specified: 0.0% - (0 of 0 people)
Lamictal:
  • < 1 month: 11.0% - (1 of 9 people)
  • 1 - 6 months: 16.0% - (4 of 24 people)
  • 6 - 12 months: 46.0% - (14 of 30 people)
  • 1 - 2 years: 44.0% - (15 of 34 people)
  • 2 - 5 years: 47.0% - (42 of 89 people)
  • 5 - 10 years: 48.0% - (28 of 58 people)
  • 10+ years: 64.0% - (11 of 17 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Lithium Carbonate:
  • female: 48.0% - (83 of 172 people)
  • male: 54.0% - (47 of 87 people)
Lamictal:
  • female: 43.0% - (74 of 171 people)
  • male: 45.0% - (41 of 91 people)

Drug effectiveness by age:

Lithium Carbonate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 46.0% - (6 of 13 people)
  • 20-29: 47.0% - (19 of 40 people)
  • 30-39: 60.0% - (39 of 65 people)
  • 40-49: 50.0% - (34 of 67 people)
  • 50-59: 40.0% - (21 of 52 people)
  • 60+: 50.0% - (11 of 22 people)
Lamictal:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 57.0% - (8 of 14 people)
  • 20-29: 50.0% - (20 of 40 people)
  • 30-39: 41.0% - (28 of 67 people)
  • 40-49: 47.0% - (33 of 70 people)
  • 50-59: 33.0% - (17 of 51 people)
  • 60+: 45.0% - (9 of 20 people)

Most common drug interactions over time *:

< 1 month:
  • drug eruption
  • pyrexia
  • rash
  • stevens-johnson syndrome
  • alanine aminotransferase increased
  • rash generalised
  • c-reactive protein increased
  • erythema
  • aspartate aminotransferase increased
  • blood lactate dehydrogenase increased
1 - 6 months:
  • pyrexia
  • rash
  • aspartate aminotransferase increased
  • drug eruption
  • mania
  • alanine aminotransferase increased
  • c-reactive protein increased
  • nausea
  • pruritus
  • rash generalised
6 - 12 months:
  • anxiety
  • emotional distress
  • injury
  • pain
  • restlessness
  • type 2 diabetes mellitus
  • blood triglycerides increased
  • infection
  • vision blurred
  • blood cholesterol increased
1 - 2 years:
  • anaemia
  • diabetes mellitus
  • hypothyroidism
  • overdose
  • suicide attempt
  • type 2 diabetes mellitus
  • cataract
  • glaucoma
  • hepatitis c
  • hyperprolactinaemia
2 - 5 years:
  • headache
  • chills
  • delirium
  • nausea
  • anxiety
  • inflammation
  • agitation
  • back pain
  • balance disorder
  • diarrhoea
5 - 10 years:
  • weight gain
  • confusion
  • depression
  • memory loss
  • anger
  • feeling hot
  • tremor
  • anxiety
  • insomnia
  • memory impairment
10+ years:
  • depression
  • anxiety
  • osteonecrosis
  • stress
  • abscess oral
  • arthralgia
  • asthenia
  • blood potassium decreased
  • diabetes insipidus
  • fall
not specified:
  • nausea
  • rash
  • pyrexia
  • weight increased
  • depression
  • vomiting
  • anxiety
  • insomnia
  • headache
  • tremor

Most common drug interactions by gender *:

female:
  • rash
  • pyrexia
  • nausea
  • anxiety
  • weight increased
  • depression
  • drug eruption
  • headache
  • insomnia
  • diarrhoea
male:
  • pyrexia
  • rash
  • nausea
  • vomiting
  • fatigue
  • mania
  • insomnia
  • pruritus
  • depression
  • stevens-johnson syndrome

Most common drug interactions by age *:

0-1:
  • amnesia
  • anorexia
  • ill-defined disorder
  • paraesthesia
  • swelling
  • weight increased
2-9:
  • aggression
  • paranoia
  • agitation
  • anger
  • hallucination, auditory
  • suicidal ideation
  • weight increased
  • educational problem
  • hostility
  • abnormal behaviour
10-19:
  • rash
  • weight increased
  • suicidal ideation
  • pyrexia
  • depression
  • headache
  • vision blurred
  • bipolar disorder
  • aggression
  • agitation
20-29:
  • rash
  • pyrexia
  • stevens-johnson syndrome
  • anxiety
  • nausea
  • drug eruption
  • dehydration
  • pruritus
  • suicidal ideation
  • hypotension
30-39:
  • nausea
  • insomnia
  • diarrhoea
  • type 2 diabetes mellitus
  • pyrexia
  • anxiety
  • vomiting
  • drug eruption
  • rash
  • tremor
40-49:
  • rash
  • depression
  • nausea
  • pyrexia
  • diabetes mellitus
  • mania
  • type 2 diabetes mellitus
  • headache
  • weight increased
  • insomnia
50-59:
  • pyrexia
  • rash
  • headache
  • depression
  • dizziness
  • weight increased
  • tremor
  • suicidal ideation
  • stevens-johnson syndrome
  • anxiety
60+:
  • pyrexia
  • rash
  • stevens-johnson syndrome
  • drug eruption
  • fall
  • erythema
  • c-reactive protein increased
  • alanine aminotransferase increased
  • depression
  • white blood cell count increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lithium carbonate (lithium carbonate) is often used to treat bipolar disorder. Lamictal (lamotrigine) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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