Review: taking Lortab and Melatonin together


Summary

Drug interactions are reported among people who take Lortab and Melatonin together. This review analyzes the effectiveness and drug interactions between Lortab and Melatonin. It is created by eHealthMe based on reports of 364 people who take the same drugs from FDA and social media, and is updated regularly.

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Lortab

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Lortab 19,656 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 4,547 users)

On Aug, 28, 2016

364 people who take Lortab, Melatonin are studied.


Number of reports submitted per year:

Lortab and Melatonin drug interactions.

Drug effectiveness over time:

Lortab:
  • < 1 month: 100.0% - (3 of 3 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 12.0% - (1 of 8 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lortab:
  • female: 43.0% - (7 of 16 people)
  • male: 25.0% - (1 of 4 people)
Melatonin:
  • female: 37.0% - (6 of 16 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Lortab:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 37.0% - (3 of 8 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 44.0% - (4 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • abnormal weight gain
  • appetite increased
  • bone pain
  • decreased activity
  • decreased interest
  • drug ineffective
  • exercise tolerance decreased
  • fall
  • heat intolerance
  • increased tendency to bruise
1 - 6 months:
  • deep vein thrombosis
  • pulmonary embolism
  • enlarged liver
  • fracture
  • hallucinations, mixed
  • vaginal sloughing
6 - 12 months:
  • enlarged liver
  • anxiety disorder
  • depression
  • hallucinations, mixed
  • sweating - excessive
2 - 5 years:
  • muscle cramps
  • fracture
  • lymphadenopathy
  • vaginal sloughing
5 - 10 years:
  • fall
  • heat intolerance
  • increased tendency to bruise
  • livedo reticularis
  • abnormal weight gain
  • appetite increased
  • bone pain
  • decreased activity
  • decreased interest
  • exercise tolerance decreased
10+ years:
  • anxiety disorder
  • depression
  • heart rate
  • sweating - excessive
not specified:
  • pain
  • back pain
  • fatigue
  • depression
  • dyspnoea
  • anxiety
  • bone disorder
  • mouth ulceration
  • osteonecrosis of jaw
  • constipation

Most common drug interactions by gender *:

female:
  • pain
  • dyspnoea
  • back pain
  • depression
  • headache
  • insomnia
  • fatigue
  • nausea
  • fall
  • osteomyelitis
male:
  • back pain
  • anxiety
  • pain
  • fatigue
  • diarrhoea
  • anaemia
  • depression
  • sinus disorder
  • bone disorder
  • gingival ulceration

Most common drug interactions by age *:

10-19:
  • pulmonary embolism
  • chest pain
  • cardiac arrest
  • convulsion
  • dyspnoea
  • thrombosis
  • cellulitis
  • circulatory collapse
  • deep vein thrombosis
  • unresponsive to stimuli
20-29:
  • deep vein thrombosis
  • cellulitis
  • osteonecrosis of jaw
  • pain
  • urinary tract infection
  • actinomyces test positive
  • acute psychosis
  • amnesia
  • asthenia
  • bone disorder
30-39:
  • pain
  • back pain
  • candidiasis
  • convulsion
  • dehydration
  • device related infection
  • pancreatitis
  • deep vein thrombosis
  • arthralgia
  • depression
40-49:
  • fatigue
  • depression
  • diarrhoea
  • pain
  • anxiety
  • sinus disorder
  • back pain
  • anaemia
  • bone disorder
  • gingival ulceration
50-59:
  • mental status changes
  • urinary tract infection
  • insomnia
  • back pain
  • depression
  • anxiety
  • decreased appetite
  • gastrooesophageal reflux disease
  • tremor
  • bone disorder
60+:
  • fall
  • pain
  • fatigue
  • back pain
  • nausea
  • arthralgia
  • pain in extremity
  • dyspnoea
  • hypertension
  • constipation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lortab (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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