Review: taking Lortab and Melatonin together


Summary

Drug interactions are reported among people who take Lortab and Melatonin together. This review analyzes the effectiveness and drug interactions between Lortab and Melatonin. It is created by eHealthMe based on reports of 630 people who take the same drugs from FDA and social media, and is updated regularly.

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Lortab

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Lortab 22,327 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 8,403 users)

On Sep, 19, 2016

630 people who take Lortab, Melatonin are studied.


Number of reports submitted per year:

Lortab and Melatonin drug interactions.

Drug effectiveness over time:

Lortab:
  • < 1 month: 100.0% - (3 of 3 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 33.0% - (2 of 6 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 12.0% - (1 of 8 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lortab:
  • female: 43.0% - (7 of 16 people)
  • male: 33.0% - (1 of 3 people)
Melatonin:
  • female: 37.0% - (6 of 16 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Lortab:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (2 of 2 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 42.0% - (3 of 7 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 44.0% - (4 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • drug ineffective
  • fall
  • abnormal weight gain
  • appetite increased
  • bone pain
  • decreased activity
  • decreased appetite
  • decreased interest
  • exercise tolerance decreased
1 - 6 months:
  • deep vein thrombosis
  • pulmonary embolism
  • enlarged liver
  • fracture
  • hallucinations, mixed
  • vaginal sloughing
6 - 12 months:
  • enlarged liver
  • anxiety disorder
  • depression
  • hallucinations, mixed
  • sweating - excessive
1 - 2 years:
  • abdominal pain
  • anxiety
  • blood calcium increased
  • coronary artery disease
  • depression
  • diarrhoea
  • disability
  • diverticulum
  • gastritis haemorrhagic
  • headache
2 - 5 years:
  • muscle cramps
  • fracture
  • lymphadenopathy
  • vaginal sloughing
5 - 10 years:
  • fall
  • heat intolerance
  • increased tendency to bruise
  • livedo reticularis
  • abnormal weight gain
  • appetite increased
  • bone pain
  • decreased activity
  • decreased interest
  • exercise tolerance decreased
10+ years:
  • anxiety disorder
  • depression
  • heart rate
  • sweating - excessive
not specified:
  • pain
  • back pain
  • fatigue
  • depression
  • dyspnoea
  • anxiety
  • asthenia
  • nausea
  • cough
  • diarrhoea

Most common drug interactions by gender *:

female:
  • pain
  • dyspnoea
  • back pain
  • fall
  • fatigue
  • nausea
  • depression
  • headache
  • insomnia
  • anxiety
male:
  • back pain
  • fatigue
  • pain
  • diarrhoea
  • depression
  • anxiety
  • anaemia
  • pain in extremity
  • pyrexia
  • swelling face

Most common drug interactions by age *:

2-9:
  • constipation
  • respiratory failure
  • vomiting
  • pleural effusion
  • pneumonitis
  • pulmonary oedema
  • pyrexia
10-19:
  • pulmonary embolism
  • chest pain
  • cardiac arrest
  • convulsion
  • dyspnoea
  • thrombosis
  • cellulitis
  • circulatory collapse
  • deep vein thrombosis
  • drug ineffective
20-29:
  • cellulitis
  • deep vein thrombosis
  • osteonecrosis of jaw
  • pain
  • urinary tract infection
  • actinomyces test positive
  • acute psychosis
  • amnesia
  • asthenia
  • bone disorder
30-39:
  • pain
  • back pain
  • nausea
  • candidiasis
  • convulsion
  • dehydration
  • device related infection
  • pancreatitis
  • sinusitis
  • deep vein thrombosis
40-49:
  • fatigue
  • depression
  • diarrhoea
  • pain
  • back pain
  • anxiety
  • sinus disorder
  • nausea
  • pyrexia
  • anaemia
50-59:
  • anxiety
  • back pain
  • depression
  • insomnia
  • cough
  • muscular weakness
  • gait disturbance
  • rash
  • diarrhoea
  • mental status changes
60+:
  • fall
  • fatigue
  • pain
  • drug ineffective
  • dyspnoea
  • nausea
  • asthenia
  • diarrhoea
  • pneumonia
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lortab (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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