Review: taking Losartan potassium and Metformin together


Summary

Drug interactions are reported among people who take Losartan potassium and Metformin together. This review analyzes the effectiveness and drug interactions between Losartan potassium and Metformin. It is created by eHealthMe based on reports of 5,639 people who take the same drugs from FDA and social media, and is updated regularly.

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Losartan Potassium

Losartan potassium has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from Losartan potassium 12,880 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 117,555 users)

On Aug, 23, 2016

5,639 people who take Losartan Potassium, Metformin are studied.


Number of reports submitted per year:

Losartan potassium and Metformin drug interactions.

Drug effectiveness over time:

Losartan Potassium:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 18.0% - (4 of 22 people)
  • 6 - 12 months: 39.0% - (9 of 23 people)
  • 1 - 2 years: 37.0% - (11 of 29 people)
  • 2 - 5 years: 43.0% - (24 of 55 people)
  • 5 - 10 years: 38.0% - (12 of 31 people)
  • 10+ years: 35.0% - (6 of 17 people)
  • not specified: 100.0% - (3 of 3 people)
Metformin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 7.0% - (1 of 13 people)
  • 6 - 12 months: 58.0% - (10 of 17 people)
  • 1 - 2 years: 43.0% - (10 of 23 people)
  • 2 - 5 years: 47.0% - (25 of 53 people)
  • 5 - 10 years: 57.0% - (31 of 54 people)
  • 10+ years: 19.0% - (4 of 21 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Losartan Potassium:
  • female: 46.0% - (43 of 93 people)
  • male: 30.0% - (27 of 90 people)
Metformin:
  • female: 48.0% - (45 of 93 people)
  • male: 39.0% - (36 of 91 people)

Drug effectiveness by age:

Losartan Potassium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 25.0% - (2 of 8 people)
  • 40-49: 33.0% - (6 of 18 people)
  • 50-59: 46.0% - (30 of 64 people)
  • 60+: 35.0% - (32 of 91 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 87.0% - (7 of 8 people)
  • 40-49: 23.0% - (5 of 21 people)
  • 50-59: 39.0% - (25 of 63 people)
  • 60+: 48.0% - (44 of 90 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • cerebrovascular accident
  • malaise
  • cough
  • visual impairment
  • headache
  • myocardial infarction
  • pruritus
  • renal failure acute
  • back pain
1 - 6 months:
  • neutropenia
  • pneumonia
  • renal failure acute
  • respiratory distress
  • upper gastrointestinal haemorrhage
  • vomiting
  • gastrointestinal toxicity
  • haematotoxicity
  • hyperkalaemia
  • mucosal inflammation
6 - 12 months:
  • renal failure acute
  • neuropathy
  • vomiting
  • chest pain
  • headache
  • nausea
  • cardiac failure congestive
  • cardiac murmur
  • cerebral infarction
  • cough
1 - 2 years:
  • hypertension
  • atherosclerosis
  • ischaemic stroke
  • type 2 diabetes mellitus
  • rash morbilliform
  • neutropenia
  • rash
  • dyspnoea
  • fall
  • heart attack
2 - 5 years:
  • hypertension
  • atherosclerosis
  • gastrointestinal haemorrhage
  • ischaemic stroke
  • type 2 diabetes mellitus
  • arthritis
  • chronic sinusitis
  • fibromyalgia
  • headache - mixed tension migraine
  • hypersomnia
5 - 10 years:
  • anaemia
  • arthritis
  • depression
  • diarrhoea
  • fall
  • angiopathy
  • anxiety
  • blood disorder
  • flatulence
  • hypoglycaemia
10+ years:
  • diarrhoea
  • renal failure acute
  • cough
  • high blood pressure
  • inherited allergies
  • malaise
  • myocardial infarction
  • nephrolithiasis
  • vomiting
  • acidosis
not specified:
  • nausea
  • blood glucose increased
  • dyspnoea
  • fatigue
  • asthenia
  • diarrhoea
  • weight decreased
  • dizziness
  • vomiting
  • drug ineffective

Most common drug interactions by gender *:

female:
  • nausea
  • dyspnoea
  • blood glucose increased
  • diarrhoea
  • dizziness
  • vomiting
  • fatigue
  • weight decreased
  • asthenia
  • fall
male:
  • blood glucose increased
  • nausea
  • asthenia
  • fatigue
  • weight decreased
  • dyspnoea
  • dizziness
  • diarrhoea
  • myocardial infarction
  • hypertension

Most common drug interactions by age *:

0-1:
  • anomaly of external ear congenital
  • arthralgia
  • polydactyly
  • premature baby
10-19:
  • vomiting
  • abdominal pain upper
  • diarrhoea
  • nausea
  • pancreatitis acute
  • pruritus
  • headache
  • acute graft versus host disease
  • body height decreased
  • cardiac disorder
20-29:
  • hypoaesthesia
  • drug ineffective
  • dizziness
  • excessive eye blinking
  • nausea
  • nephrolithiasis
  • pain - foot
  • pain in extremity
  • tiredness
  • vaginal itching
30-39:
  • fatigue
  • weight decreased
  • anxiety
  • asthenia
  • myalgia
  • injury
  • type 2 diabetes mellitus
  • urinary tract infection
  • dysphagia
  • muscle spasms
40-49:
  • nausea
  • renal failure acute
  • lactic acidosis
  • weight decreased
  • vomiting
  • diarrhoea
  • back pain
  • blood glucose increased
  • myocardial infarction
  • diabetes mellitus
50-59:
  • nausea
  • blood glucose increased
  • diarrhoea
  • vomiting
  • weight decreased
  • dyspnoea
  • fatigue
  • dizziness
  • headache
  • pain
60+:
  • nausea
  • blood glucose increased
  • dyspnoea
  • dizziness
  • asthenia
  • diarrhoea
  • fatigue
  • vomiting
  • renal failure acute
  • hypertension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Losartan potassium (losartan potassium) is often used to treat high blood pressure. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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