Review: taking Losartan and Benadryl together


Summary

Drug interactions are reported among people who take Losartan and Benadryl together. This review analyzes the effectiveness and drug interactions between Losartan and Benadryl. It is created by eHealthMe based on reports of 471 people who take the same drugs from FDA and social media, and is updated regularly.

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Losartan

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from Losartan 18,152 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 29,242 users)

On Jul, 27, 2016

471 people who take Losartan, Benadryl are studied.


Number of reports submitted per year:

Losartan and Benadryl drug interactions.

Drug effectiveness over time:

Losartan:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Losartan:
  • female: 33.0% - (2 of 6 people)
  • male: 25.0% - (1 of 4 people)
Benadryl:
  • female: 60.0% - (3 of 5 people)
  • male: 0.0% - (0 of 4 people)

Drug effectiveness by age:

Losartan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 20.0% - (1 of 5 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • anxiety
  • fear
  • pain
  • renal impairment
  • renal injury
  • stress
  • dysphagia
  • emotional distress
  • death
1 - 6 months:
  • dry mouth
  • tooth loss
  • tooth extraction
  • atrial fibrillation
  • myocardial infarction
  • sepsis
  • tooth discolouration
  • urinary tract infection
  • adrenal insufficiency
  • aortic valve sclerosis
6 - 12 months:
  • bone loss
1 - 2 years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • lupus nephritis
  • systemic lupus erythematosus
  • vision blurred
  • pneumonia
  • stroke
  • tumour lysis syndrome
  • bone loss
  • dry skin
2 - 5 years:
  • hematospermia
  • dry skin
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • vision blurred
5 - 10 years:
  • hematospermia
not specified:
  • dyspnoea
  • diarrhoea
  • fatigue
  • chest pain
  • anxiety
  • pain
  • constipation
  • nausea
  • osteonecrosis of jaw
  • cough

Most common drug interactions by gender *:

female:
  • diarrhoea
  • anxiety
  • nausea
  • dyspnoea
  • pain
  • fatigue
  • pain in extremity
  • back pain
  • vomiting
  • fall
male:
  • dyspnoea
  • chest pain
  • constipation
  • diarrhoea
  • gait disturbance
  • arthralgia
  • fatigue
  • depression
  • anaemia
  • hypoaesthesia

Most common drug interactions by age *:

2-9:
  • bacillus infection
10-19:
  • hypotension
  • anaemia
  • aplasia pure red cell
  • arteriovenous fistula occlusion
  • arteriovenous fistula thrombosis
  • bone marrow myelogram abnormal
  • diarrhoea
  • focal segmental glomerulosclerosis
  • gastroenteritis
  • renal failure
20-29:
  • dizziness
  • loss of consciousness
  • ventricular fibrillation
  • visual impairment
30-39:
  • neck pain
  • chest pain
  • diabetes mellitus
  • tremor
  • anxiety
  • arthralgia
  • difficulty in walking
  • fatigue
  • gait disturbance
  • hypoaesthesia
40-49:
  • diabetes mellitus
  • abasia
  • blood creatinine increased
  • blood potassium increased
  • depression
  • dyspnoea
  • fatigue
  • injury
  • neuroleptic malignant syndrome
  • pyrexia
50-59:
  • anxiety
  • pain
  • dyspnoea
  • nausea
  • vomiting
  • pain in extremity
  • weight increased
  • cough
  • headache
  • hypertension
60+:
  • diarrhoea
  • fatigue
  • dyspnoea
  • chest pain
  • osteoporosis
  • osteopenia
  • constipation
  • anaemia
  • dizziness
  • osteonecrosis of jaw

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Losartan (losartan potassium) is often used to treat high blood pressure. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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