Review: taking Losartan and Norvasc together


Summary

Drug interactions are reported among people who take Losartan and Norvasc together. This review analyzes the effectiveness and drug interactions between Losartan and Norvasc. It is created by eHealthMe based on reports of 4,382 people who take the same drugs from FDA and social media, and is updated regularly.

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Losartan

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from Losartan 18,152 users)

Norvasc

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Norvasc 79,416 users)

On Jul, 24, 2016

4,382 people who take Losartan, Norvasc are studied.


Number of reports submitted per year:

Losartan and Norvasc drug interactions.

Drug effectiveness over time:

Losartan:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 21.0% - (3 of 14 people)
  • 6 - 12 months: 13.0% - (2 of 15 people)
  • 1 - 2 years: 27.0% - (8 of 29 people)
  • 2 - 5 years: 50.0% - (20 of 40 people)
  • 5 - 10 years: 46.0% - (14 of 30 people)
  • 10+ years: 20.0% - (2 of 10 people)
  • not specified: 0.0% - (0 of 0 people)
Norvasc:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 26.0% - (4 of 15 people)
  • 6 - 12 months: 50.0% - (11 of 22 people)
  • 1 - 2 years: 38.0% - (7 of 18 people)
  • 2 - 5 years: 51.0% - (24 of 47 people)
  • 5 - 10 years: 21.0% - (4 of 19 people)
  • 10+ years: 15.0% - (2 of 13 people)
  • not specified: 0.0% - (0 of 5 people)

Drug effectiveness by gender:

Losartan:
  • female: 40.0% - (24 of 60 people)
  • male: 29.0% - (25 of 84 people)
Norvasc:
  • female: 38.0% - (23 of 59 people)
  • male: 33.0% - (29 of 86 people)

Drug effectiveness by age:

Losartan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 53.0% - (8 of 15 people)
  • 50-59: 37.0% - (20 of 54 people)
  • 60+: 26.0% - (19 of 71 people)
Norvasc:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 50.0% - (7 of 14 people)
  • 50-59: 49.0% - (26 of 53 people)
  • 60+: 24.0% - (18 of 73 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • oedema peripheral
  • confusional state
  • blood pressure increased
  • headache
  • hypotension
  • burning sensation
  • cystitis
  • dyspnoea
  • ingrowing nail
1 - 6 months:
  • pneumonia
  • neutropenia
  • respiratory distress
  • upper gastrointestinal haemorrhage
  • haemoglobin decreased
  • hypertension
  • cerebrovascular accident
  • international normalised ratio decreased
  • renal failure
  • alanine aminotransferase increased
6 - 12 months:
  • hypertension
  • myocardial infarction
  • cerebrovascular accident
  • brain stem haemorrhage
  • cardiac failure congestive
  • nausea
  • renal failure chronic
  • blood creatinine increased
  • cardiac failure
  • cardiovascular disorder
1 - 2 years:
  • dizziness
  • acid reflux
  • allergies
  • gouty arthritis
  • high blood pressure
  • blood pressure increased
  • palpitations
  • anaemia
  • aplasia pure red cell
  • insomnia
2 - 5 years:
  • hypertension
  • heart rate increased
  • panic attack
  • arthralgia
  • irritable bowel syndrome
  • nausea
  • abdominal pain upper
  • diarrhoea
  • dizziness
  • dyspnoea
5 - 10 years:
  • dizziness
  • cerebrovascular accident
  • constipation
  • myocardial infarction
  • abdominal pain
  • anaemia
  • angina unstable
  • chest pain
  • encephalopathy
  • fall
10+ years:
  • anxiety
  • chest pain
  • coronary artery disease
  • dental caries
  • depression
  • diabetes mellitus
  • diarrhea associated with medications
  • lung disorder
  • muscle cramps
  • myocardial infarction
not specified:
  • dizziness
  • nausea
  • dyspnoea
  • pain
  • headache
  • fatigue
  • hypertension
  • oedema peripheral
  • drug ineffective
  • chest pain

Most common drug interactions by gender *:

female:
  • dizziness
  • headache
  • hypertension
  • nausea
  • dyspnoea
  • weight decreased
  • blood pressure increased
  • pain
  • oedema peripheral
  • chest pain
male:
  • fatigue
  • dyspnoea
  • pain
  • nausea
  • dizziness
  • anxiety
  • malaise
  • oedema peripheral
  • drug ineffective
  • asthenia

Most common drug interactions by age *:

0-1:
  • chest pain
  • haemolytic uraemic syndrome
  • nephrotic syndrome
  • proteinuria
  • pulmonary embolism
  • skin atrophy
2-9:
  • abdominal distension
  • device related infection
  • drug administration error
  • haemolytic uraemic syndrome
  • hypertensive crisis
  • pericardial effusion
  • urinary tract infection
  • angioedema
  • aspiration bone marrow abnormal
  • auricular swelling
10-19:
  • infection
  • lupus nephritis
  • systemic lupus erythematosus
  • hypotension
  • arteriovenous fistula occlusion
  • arteriovenous fistula thrombosis
  • blood alkaline phosphatase increased
  • blood immunoglobulin m increased
  • blood lactate dehydrogenase increased
  • blood urea increased
20-29:
  • abdominal pain
  • anaemia
  • asthenia
  • dehydration
  • dyspnoea
  • gastrointestinal disorder
  • haemorrhage
  • hypotension
  • nausea
  • vomiting
30-39:
  • renal failure
  • anxiety
  • pain
  • emotional distress
  • fear
  • renal impairment
  • renal injury
  • stress
  • anaemia
  • chest pain
40-49:
  • fatigue
  • pain
  • asthenia
  • headache
  • cardiac failure congestive
  • chest pain
  • dizziness
  • nausea
  • back pain
  • arthralgia
50-59:
  • dizziness
  • headache
  • drug ineffective
  • weight decreased
  • blood pressure increased
  • hypertension
  • hypotension
  • anaemia
  • loss of consciousness
  • palpitations
60+:
  • nausea
  • dizziness
  • dyspnoea
  • oedema peripheral
  • pain
  • hypertension
  • fatigue
  • chest pain
  • diarrhoea
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Losartan (losartan potassium) is often used to treat high blood pressure. Norvasc (amlodipine besylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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