Review: taking Losartan and Norvasc together


Summary

Drug interactions are reported among people who take Losartan and Norvasc together. This review analyzes the effectiveness and drug interactions between Losartan and Norvasc. It is created by eHealthMe based on reports of 6,581 people who take the same drugs from FDA and social media, and is updated regularly.

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Losartan

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from Losartan 23,077 users)

Norvasc

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Norvasc 85,611 users)

On Aug, 20, 2016

6,581 people who take Losartan, Norvasc are studied.


Number of reports submitted per year:

Losartan and Norvasc drug interactions.

Drug effectiveness over time:

Losartan:
  • < 1 month: 12.0% - (1 of 8 people)
  • 1 - 6 months: 21.0% - (6 of 28 people)
  • 6 - 12 months: 37.0% - (10 of 27 people)
  • 1 - 2 years: 37.0% - (14 of 37 people)
  • 2 - 5 years: 40.0% - (23 of 57 people)
  • 5 - 10 years: 50.0% - (18 of 36 people)
  • 10+ years: 29.0% - (5 of 17 people)
  • not specified: 0.0% - (0 of 1 people)
Norvasc:
  • < 1 month: 0.0% - (0 of 7 people)
  • 1 - 6 months: 33.0% - (9 of 27 people)
  • 6 - 12 months: 40.0% - (11 of 27 people)
  • 1 - 2 years: 55.0% - (16 of 29 people)
  • 2 - 5 years: 53.0% - (34 of 64 people)
  • 5 - 10 years: 26.0% - (7 of 26 people)
  • 10+ years: 27.0% - (6 of 22 people)
  • not specified: 0.0% - (0 of 4 people)

Drug effectiveness by gender:

Losartan:
  • female: 39.0% - (37 of 93 people)
  • male: 33.0% - (40 of 118 people)
Norvasc:
  • female: 42.0% - (37 of 88 people)
  • male: 38.0% - (46 of 118 people)

Drug effectiveness by age:

Losartan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 48.0% - (12 of 25 people)
  • 50-59: 33.0% - (25 of 75 people)
  • 60+: 35.0% - (36 of 102 people)
Norvasc:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 37.0% - (3 of 8 people)
  • 40-49: 58.0% - (14 of 24 people)
  • 50-59: 42.0% - (30 of 71 people)
  • 60+: 35.0% - (36 of 101 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • blood pressure increased
  • headache
  • oedema peripheral
  • confusional state
  • malaise
  • burning sensation
  • dyspnoea
  • fatigue
  • palpitations
1 - 6 months:
  • dyspnoea
  • pneumonia
  • oedema peripheral
  • neutropenia
  • respiratory distress
  • upper gastrointestinal haemorrhage
  • gastrointestinal haemorrhage
  • haemoglobin decreased
  • hypertension
  • renal failure
6 - 12 months:
  • accelerated idioventricular rhythm
  • collapse
  • loss of consciousness
  • arthritis
  • nausea
  • hypertension
  • myocardial infarction
  • pruritus generalised
  • unresponsive to stimuli
  • cerebrovascular accident
1 - 2 years:
  • hypertension
  • atherosclerosis
  • ischaemic stroke
  • type 2 diabetes mellitus
  • dizziness
  • acid reflux
  • allergies
  • gouty arthritis
  • high blood pressure
  • anaemia
2 - 5 years:
  • heart rate increased
  • hypertension
  • panic attack
  • arthralgia
  • irritable bowel syndrome
  • nausea
  • abdominal pain upper
  • diarrhoea
  • dizziness
  • pneumonia
5 - 10 years:
  • dizziness
  • cerebrovascular accident
  • memory impairment
  • constipation
  • cognitive deterioration
  • myocardial infarction
  • anaemia
  • change in sustained attention
  • coronary artery disease
  • dyspnoea
10+ years:
  • memory impairment
  • anxiety
  • change in sustained attention
  • cognitive deterioration
  • depression
  • arteriosclerosis coronary artery
  • central nervous system lesion
  • chest pain
  • coronary artery disease
  • dental caries
not specified:
  • dyspnoea
  • nausea
  • fatigue
  • dizziness
  • pain
  • drug ineffective
  • hypertension
  • headache
  • arthralgia
  • diarrhoea

Most common drug interactions by gender *:

female:
  • dizziness
  • hypertension
  • nausea
  • headache
  • dyspnoea
  • drug ineffective
  • pain
  • blood pressure increased
  • fatigue
  • arthralgia
male:
  • fatigue
  • dyspnoea
  • nausea
  • pain
  • dizziness
  • drug ineffective
  • anxiety
  • arthralgia
  • malaise
  • myalgia

Most common drug interactions by age *:

0-1:
  • pulmonary embolism
  • proteinuria
  • haemolytic uraemic syndrome
  • nephrotic syndrome
  • cardio-respiratory arrest
  • chest pain
  • glomerular filtration rate decreased
  • grand mal convulsion
  • herpes zoster
  • hypertension
2-9:
  • device related infection
  • abdominal distension
  • drug administration error
  • haemolytic uraemic syndrome
  • hypertensive crisis
  • pericardial effusion
  • pneumonia
  • respiratory syncytial virus infection
  • urinary tract infection
  • angioedema
10-19:
  • cardiac arrest
  • cardiac failure congestive
  • infection
  • lupus nephritis
  • nausea
  • rectal bleeding
  • systemic lupus erythematosus
  • apnoea
  • hypertension
  • hypotension
20-29:
  • abdominal pain
  • hypoaesthesia
  • anaemia
  • abdominal distension
  • dizziness
  • drug ineffective
  • hypertension
  • injection site pain
  • weight decreased
  • nausea
30-39:
  • renal failure
  • completed suicide
  • dizziness
  • arthritis
  • bronchitis
  • neuropathy peripheral
  • pain
  • anxiety
  • cholelithiasis
  • glaucoma
40-49:
  • fatigue
  • headache
  • pain
  • arthralgia
  • asthenia
  • dizziness
  • nausea
  • anxiety
  • diarrhoea
  • hypertension
50-59:
  • blood pressure increased
  • dizziness
  • headache
  • dyspnoea
  • drug ineffective
  • hypertension
  • weight decreased
  • fatigue
  • nausea
  • loss of consciousness
60+:
  • dyspnoea
  • nausea
  • dizziness
  • fatigue
  • pain
  • hypertension
  • diarrhoea
  • oedema peripheral
  • drug ineffective
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Losartan (losartan potassium) is often used to treat high blood pressure. Norvasc (amlodipine besylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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