Lunesta and Benadryl drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Lunesta and Benadryl together. This review analyzes the effectiveness and drug interactions between Lunesta and Benadryl. It is created by eHealthMe based on reports of 605 people who take the same drugs from FDA, and is updated regularly.

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Lunesta

Lunesta has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from Lunesta 19,099 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 44,713 users)

On Jan, 27, 2017

605 people who take Lunesta, Benadryl are studied.


Number of reports submitted per year:

Lunesta and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • infusion related reaction
  • nasopharyngitis
  • bowen's disease
  • basal cell carcinoma
  • gastroenteritis
  • catheter site pain
  • lower respiratory tract infection
  • nerve compression
  • pain in extremity
1 - 6 months:
  • dementia
  • pancreatitis
  • plasma cell myeloma
  • pre-existing condition improved
  • therapeutic response unexpected
  • abdominal pain
  • chills
  • chronic obstructive pulmonary disease
  • colitis
  • confusional state
6 - 12 months:
  • b-cell lymphoma
  • ureteric obstruction
  • accidental overdose
  • chronic obstructive pulmonary disease
  • depression
  • dysphagia
  • insomnia
  • renal failure acute
  • abnormal dreams
  • arrhythmia
1 - 2 years:
  • b-cell lymphoma
  • ureteric obstruction
  • atrial septal defect
  • cardiac failure congestive
  • cardiomegaly
  • congenital cardiovascular anomaly
  • drug exposure during pregnancy
  • pleural effusion
  • rash
  • renal failure acute
2 - 5 years:
  • b-cell lymphoma
  • ureteric obstruction
  • renal failure acute
  • chronic graft versus host disease
  • pruritus
  • pulmonary mycosis
  • urticaria
5 - 10 years:
  • abdominal abscess
  • convulsion
  • drug ineffective
  • hangover
  • migraine
  • post procedural bile leak
  • pyrexia
10+ years:
  • activities of daily living impaired
  • arthralgia
  • body temperature fluctuation
  • carpal tunnel decompression
  • chills
  • cough
  • dysgeusia
  • dysuria
  • fatigue
  • hyperhidrosis
not specified:
  • pain
  • fatigue
  • nausea
  • arthralgia
  • infusion related reaction
  • pain in extremity
  • weight decreased
  • depression
  • headache
  • drug ineffective

Most common drug interactions by gender *:

female:
  • infusion related reaction
  • fatigue
  • nausea
  • arthralgia
  • pain
  • pain in extremity
  • weight decreased
  • depression
  • insomnia
  • pyrexia
male:
  • pneumonia
  • anxiety
  • weight decreased
  • asthenia
  • fatigue
  • pain
  • back pain
  • osteonecrosis of jaw
  • drug ineffective
  • fall

Most common drug interactions by age *:

0-1:
  • abdominal discomfort
  • depression
  • insomnia
  • palpitations
  • panic disorder
  • weight decreased
10-19:
  • pancreatitis
  • abdominal pain
  • abdominal pain upper
  • hypokinesia
  • initial insomnia
  • neck pain
  • somnolence
  • suicide attempt
  • tardive dyskinesia
20-29:
  • abdominal pain
  • depression
  • back pain
  • haemoglobin decreased
  • headache
  • insomnia
  • pyrexia
  • anxiety
  • nausea
  • cardiomegaly
30-39:
  • arthralgia
  • infusion related reaction
  • pain in extremity
  • contusion
  • fatigue
  • asthma
  • balance disorder
  • blood glucose decreased
  • blood potassium decreased
  • drug administration error
40-49:
  • pain
  • back pain
  • depression
  • diarrhoea
  • pain in extremity
  • anxiety
  • fatigue
  • infusion related reaction
  • weight decreased
  • intervertebral disc protrusion
50-59:
  • infusion related reaction
  • pain in extremity
  • pyrexia
  • nausea
  • pain
  • nasopharyngitis
  • fatigue
  • hypotension
  • drug ineffective
  • arthralgia
60+:
  • infusion related reaction
  • drug ineffective
  • headache
  • nausea
  • arthralgia
  • fatigue
  • pain
  • hypertension
  • pneumonia
  • rheumatoid arthritis

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lunesta and Benadryl?

Interactions between Lunesta and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Benadryl and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Lunesta (eszopiclone) is often used to treat insomnia. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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