Lyrica and Keppra drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Lyrica and Keppra together. This review analyzes the effectiveness and drug interactions between Lyrica and Keppra. It is created by eHealthMe based on reports of 1,454 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Lyrica and Keppra, find out what symptoms you could have in 1 year or longer.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 126,949 users)

Keppra

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. (latest outcomes from Keppra 37,183 users)

On Jan, 30, 2017

1,454 people who take Lyrica, Keppra are studied.


Number of reports submitted per year:

Lyrica and Keppra drug interactions.

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • coma
  • posterior reversible encephalopathy syndrome
  • suicide attempt
  • convulsion
  • dizziness
  • nausea
  • feeling abnormal
  • vertigo
  • agranulocytosis
1 - 6 months:
  • agitation
  • convulsion
  • onychophagia
  • self injurious behaviour
  • dizziness
  • fatigue
  • headache
  • depression
  • epilepsy
  • pneumonia
6 - 12 months:
  • foetal exposure during pregnancy
  • premature baby
  • abnormal palmar/plantar creases
  • dysmorphism
  • somnolence
  • fall
  • confusional state
  • convulsion
  • disturbance in attention
  • loss of consciousness
1 - 2 years:
  • fatigue
  • drug ineffective
  • drug hypersensitivity
  • malaise
  • nausea
  • burning sensation
  • convulsion
  • depression
  • depression suicidal
  • headache
2 - 5 years:
  • convulsion
  • somnolence
  • insomnia
  • irritability
  • muscular weakness
  • pain
  • abortion spontaneous
  • adrenal insufficiency
  • anuria
  • circulatory collapse
5 - 10 years:
  • pain
  • accidental overdose
  • asthenia
  • back injury
  • back pain
  • cataract
  • cerebrovascular accident
  • complex partial seizures
  • convulsion
  • drug ineffective
not specified:
  • convulsion
  • drug ineffective
  • fatigue
  • somnolence
  • weight increased
  • dizziness
  • seizure
  • fall
  • nausea
  • pain

Most common drug interactions by gender *:

female:
  • convulsion
  • fatigue
  • somnolence
  • weight increased
  • drug ineffective
  • dizziness
  • nausea
  • pain
  • headache
  • insomnia
male:
  • convulsion
  • drug ineffective
  • fall
  • somnolence
  • seizure
  • fatigue
  • overdose
  • dizziness
  • insomnia
  • partial seizures

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • low birth weight baby
  • premature baby
  • cyanosis
  • epilepsy
  • drug ineffective
  • metabolic acidosis
  • status epilepticus
  • anxiety
  • bradyphrenia
2-9:
  • metabolic acidosis
  • convulsion
  • drug ineffective
  • acidosis hyperchloraemic
  • calculus urinary
  • haemodynamic instability
  • rash
  • rebound effect
  • therapeutic response decreased
10-19:
  • convulsion
  • irritability
  • back pain
  • cervical vertebral fracture
  • abdominal wall haematoma
  • aggression
  • bacterial infection
  • blood pressure increased
  • bone marrow reticulin fibrosis
  • diplopia
20-29:
  • convulsion
  • drug ineffective
  • pyrexia
  • epilepsy
  • coma
  • status epilepticus
  • suicide attempt
  • drug exposure during pregnancy
  • pneumonia
  • seizure
30-39:
  • convulsion
  • weight increased
  • fatigue
  • dizziness
  • drug ineffective
  • cardiac arrest
  • overdose
  • memory impairment
  • accidental poisoning
  • fall
40-49:
  • convulsion
  • somnolence
  • dizziness
  • drug ineffective
  • fatigue
  • pain
  • ataxia
  • headache
  • tremor
  • muscular weakness
50-59:
  • convulsion
  • fatigue
  • epilepsy
  • drug ineffective
  • weight increased
  • nausea
  • headache
  • pain
  • fall
  • somnolence
60+:
  • convulsion
  • drug ineffective
  • fatigue
  • fall
  • somnolence
  • nausea
  • pain
  • weight increased
  • confusional state
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Lyrica and Keppra?

Interactions between Lyrica and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Keppra and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Keppra (levetiracetam) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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