Review: taking Lyrica and Levothyroxine sodium together


Summary

Drug interactions are reported among people who take Lyrica and Levothyroxine sodium together. This review analyzes the effectiveness and drug interactions between Lyrica and Levothyroxine sodium. It is created by eHealthMe based on reports of 8,928 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 121,583 users)

Levothyroxine Sodium

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Levothyroxine sodium 74,676 users)

On Sep, 17, 2016

8,928 people who take Lyrica, Levothyroxine Sodium are studied.


Number of reports submitted per year:

Lyrica and Levothyroxine sodium drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 0.0% - (0 of 13 people)
  • 1 - 6 months: 33.0% - (12 of 36 people)
  • 6 - 12 months: 37.0% - (11 of 29 people)
  • 1 - 2 years: 34.0% - (10 of 29 people)
  • 2 - 5 years: 43.0% - (18 of 41 people)
  • 5 - 10 years: 45.0% - (9 of 20 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 3 people)
Levothyroxine Sodium:
  • < 1 month: 75.0% - (3 of 4 people)
  • 1 - 6 months: 44.0% - (4 of 9 people)
  • 6 - 12 months: 50.0% - (4 of 8 people)
  • 1 - 2 years: 42.0% - (8 of 19 people)
  • 2 - 5 years: 55.0% - (19 of 34 people)
  • 5 - 10 years: 67.0% - (21 of 31 people)
  • 10+ years: 75.0% - (57 of 76 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lyrica:
  • female: 36.0% - (55 of 149 people)
  • male: 32.0% - (9 of 28 people)
Levothyroxine Sodium:
  • female: 61.0% - (93 of 151 people)
  • male: 76.0% - (23 of 30 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 40.0% - (2 of 5 people)
  • 30-39: 35.0% - (6 of 17 people)
  • 40-49: 28.0% - (12 of 42 people)
  • 50-59: 37.0% - (22 of 58 people)
  • 60+: 40.0% - (22 of 54 people)
Levothyroxine Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 66.0% - (12 of 18 people)
  • 40-49: 60.0% - (25 of 41 people)
  • 50-59: 66.0% - (40 of 60 people)
  • 60+: 65.0% - (36 of 55 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • drug ineffective
  • pain
  • fall
  • vision blurred
  • feeling abnormal
  • somnolence
  • fatigue
  • gait disturbance
  • depression
1 - 6 months:
  • pain
  • drug ineffective
  • weight increased
  • oedema peripheral
  • nausea
  • pain in extremity
  • somnolence
  • gait disturbance
  • dizziness
  • fall
6 - 12 months:
  • pain
  • dizziness
  • fall
  • drug ineffective
  • gait disturbance
  • nausea
  • weight increased
  • malaise
  • decreased appetite
  • depression
1 - 2 years:
  • weight increased
  • drug ineffective
  • pain
  • fall
  • vision blurred
  • dyspnoea
  • dizziness
  • fatigue
  • malaise
  • memory impairment
2 - 5 years:
  • fibromyalgia
  • headache
  • pain
  • fatigue - chronic
  • hypothyroidism
  • drug ineffective
  • menopause
  • temporomandibular joint syndrome
  • gait disturbance
  • balance disorder
5 - 10 years:
  • nausea
  • pain
  • burning sensation
  • malaise
  • anxiety
  • night sweats
  • sickness
  • depression
  • fatigue
  • vision blurred
10+ years:
  • insomnia exacerbated
  • anxiety
  • confusion
  • confusional state
  • dry mouth
  • edema
  • constipation
  • depression
  • fever
  • frequent headaches
not specified:
  • pain
  • drug ineffective
  • dizziness
  • nausea
  • fatigue
  • fall
  • pain in extremity
  • headache
  • weight increased
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • dizziness
  • nausea
  • fatigue
  • fall
  • weight increased
  • headache
  • pain in extremity
  • dyspnoea
male:
  • pain
  • drug ineffective
  • nausea
  • dizziness
  • pain in extremity
  • fatigue
  • dyspnoea
  • fall
  • oedema peripheral
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • lipoma
  • neural tube defect
  • plasmacytoma
  • spina bifida
2-9:
  • abnormal behaviour
  • aggression
  • depressed level of consciousness
  • haemolytic anaemia
  • lethargy
  • meningitis aseptic
  • pancreatitis
  • thrombocytosis
10-19:
  • migraine
  • muscle spasms
  • muscle twitching
  • pain
  • papilloedema
  • visual disturbance
  • anxiety
  • asthenia
  • dyspnoea
  • injection site pain
20-29:
  • drug ineffective
  • nausea
  • liver injury
  • back pain
  • abdominal pain
  • balance disorder
  • fall
  • dizziness
  • agitation
  • cardiac arrest
30-39:
  • pain
  • nausea
  • fatigue
  • headache
  • dizziness
  • arthralgia
  • intervertebral disc protrusion
  • abdominal pain
  • drug ineffective
  • diarrhoea
40-49:
  • pain
  • nausea
  • back pain
  • drug ineffective
  • headache
  • weight increased
  • depression
  • fatigue
  • anxiety
  • dizziness
50-59:
  • pain
  • drug ineffective
  • nausea
  • fatigue
  • headache
  • weight increased
  • pain in extremity
  • malaise
  • fall
  • dizziness
60+:
  • pain
  • drug ineffective
  • dizziness
  • fall
  • fatigue
  • pain in extremity
  • nausea
  • dyspnoea
  • gait disturbance
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Levothyroxine sodium (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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