Review: taking Lyrica and Levothyroxine sodium together


Summary

Drug interactions are reported among people who take Lyrica and Levothyroxine sodium together. This review analyzes the effectiveness and drug interactions between Lyrica and Levothyroxine sodium. It is created by eHealthMe based on reports of 4,908 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 64,308 users)

Levothyroxine Sodium

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Levothyroxine sodium 64,698 users)

On Jul, 24, 2016

4,908 people who take Lyrica, Levothyroxine Sodium are studied.


Number of reports submitted per year:

Lyrica and Levothyroxine sodium drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 0.0% - (0 of 15 people)
  • 1 - 6 months: 36.0% - (15 of 41 people)
  • 6 - 12 months: 45.0% - (16 of 35 people)
  • 1 - 2 years: 38.0% - (13 of 34 people)
  • 2 - 5 years: 36.0% - (21 of 57 people)
  • 5 - 10 years: 45.0% - (11 of 24 people)
  • 10+ years: 66.0% - (6 of 9 people)
  • not specified: 0.0% - (0 of 3 people)
Levothyroxine Sodium:
  • < 1 month: 66.0% - (4 of 6 people)
  • 1 - 6 months: 44.0% - (4 of 9 people)
  • 6 - 12 months: 50.0% - (4 of 8 people)
  • 1 - 2 years: 40.0% - (8 of 20 people)
  • 2 - 5 years: 41.0% - (20 of 48 people)
  • 5 - 10 years: 69.0% - (27 of 39 people)
  • 10+ years: 71.0% - (67 of 94 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Lyrica:
  • female: 38.0% - (72 of 187 people)
  • male: 32.0% - (10 of 31 people)
Levothyroxine Sodium:
  • female: 57.0% - (109 of 191 people)
  • male: 75.0% - (25 of 33 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 20.0% - (1 of 5 people)
  • 30-39: 35.0% - (7 of 20 people)
  • 40-49: 34.0% - (18 of 52 people)
  • 50-59: 36.0% - (28 of 77 people)
  • 60+: 44.0% - (28 of 63 people)
Levothyroxine Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 66.0% - (14 of 21 people)
  • 40-49: 57.0% - (31 of 54 people)
  • 50-59: 57.0% - (46 of 80 people)
  • 60+: 64.0% - (40 of 62 people)

Most common drug interactions over time *:

< 1 month:
  • dizziness
  • drug ineffective
  • fall
  • pain
  • feeling abnormal
  • fatigue
  • depression
  • gait disturbance
  • vision blurred
  • hyponatraemia
1 - 6 months:
  • pain
  • weight increased
  • oedema peripheral
  • drug ineffective
  • pain in extremity
  • somnolence
  • dizziness
  • gait disturbance
  • fall
  • headache
6 - 12 months:
  • dizziness
  • drug ineffective
  • fall
  • gait disturbance
  • pain
  • weight increased
  • amnesia
  • disorientation
  • febrile neutropenia
  • swelling
1 - 2 years:
  • weight increased
  • memory impairment
  • vision blurred
  • dizziness
  • fall
  • pain
  • dyspnoea
  • depression
  • dysarthria
  • fatigue
2 - 5 years:
  • headache
  • fibromyalgia
  • fatigue - chronic
  • hypothyroidism
  • menopause
  • temporomandibular joint syndrome
  • balance disorder
  • drug ineffective
  • gait disturbance
  • weight increased
5 - 10 years:
  • nausea
  • burning sensation
  • sickness
  • malaise
  • night sweats
  • agitation
  • anxiety
  • breath odour
  • constipation
  • shaking palsy
10+ years:
  • insomnia exacerbated
  • confusion
  • dry mouth
  • edema
  • anxiety
  • constipation
  • depression
  • fever
  • frequent headaches
  • loss of libido
not specified:
  • pain
  • dizziness
  • drug ineffective
  • nausea
  • fatigue
  • oedema peripheral
  • weight increased
  • dyspnoea
  • fall
  • somnolence

Most common drug interactions by gender *:

female:
  • pain
  • dizziness
  • drug ineffective
  • fatigue
  • nausea
  • weight increased
  • oedema peripheral
  • fall
  • dyspnoea
  • somnolence
male:
  • pain
  • drug ineffective
  • dizziness
  • oedema peripheral
  • renal failure acute
  • back pain
  • nausea
  • dyspnoea
  • pain in extremity
  • fall

Most common drug interactions by age *:

2-9:
  • depressed level of consciousness
  • lethargy
10-19:
  • migraine
  • muscle spasms
  • muscle twitching
  • papilloedema
  • visual disturbance
  • visual field defect
  • wisdom teeth removal
  • acne
  • drug ineffective
  • pain
20-29:
  • asthenia
  • back pain
  • paraesthesia
  • pyrexia
  • abdominal pain
  • adhesion
  • anxiety
  • endometriosis
  • injury
  • loss of consciousness
30-39:
  • pain
  • fatigue
  • nausea
  • headache
  • dizziness
  • arthralgia
  • intervertebral disc protrusion
  • abdominal pain
  • hodgkin's disease
  • decreased appetite
40-49:
  • pain
  • back pain
  • oedema peripheral
  • depression
  • weight increased
  • nausea
  • convulsion
  • anxiety
  • dizziness
  • dyspnoea
50-59:
  • pain
  • fatigue
  • drug ineffective
  • weight increased
  • nausea
  • oedema peripheral
  • somnolence
  • headache
  • dyspnoea
  • dizziness
60+:
  • dizziness
  • pain
  • fall
  • drug ineffective
  • fatigue
  • nausea
  • oedema peripheral
  • dyspnoea
  • diarrhoea
  • weight increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Levothyroxine sodium (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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