Review: taking Lyrica and Morphine sulfate together


Summary

Drug interactions are reported among people who take Lyrica and Morphine sulfate together. This review analyzes the effectiveness and drug interactions between Lyrica and Morphine sulfate. It is created by eHealthMe based on reports of 3,290 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 86,359 users)

Morphine Sulfate

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. (latest outcomes from Morphine sulfate 21,770 users)

On Aug, 31, 2016

3,290 people who take Lyrica, Morphine Sulfate are studied.


Number of reports submitted per year:

Lyrica and Morphine sulfate drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 14.0% - (3 of 21 people)
  • 6 - 12 months: 33.0% - (3 of 9 people)
  • 1 - 2 years: 20.0% - (2 of 10 people)
  • 2 - 5 years: 33.0% - (6 of 18 people)
  • 5 - 10 years: 12.0% - (1 of 8 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 2 people)
Morphine Sulfate:
  • < 1 month: 54.0% - (6 of 11 people)
  • 1 - 6 months: 15.0% - (3 of 19 people)
  • 6 - 12 months: 71.0% - (5 of 7 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 47.0% - (8 of 17 people)
  • 5 - 10 years: 12.0% - (1 of 8 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Lyrica:
  • female: 21.0% - (11 of 51 people)
  • male: 24.0% - (6 of 25 people)
Morphine Sulfate:
  • female: 34.0% - (18 of 52 people)
  • male: 34.0% - (9 of 26 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 42.0% - (3 of 7 people)
  • 30-39: 21.0% - (4 of 19 people)
  • 40-49: 25.0% - (4 of 16 people)
  • 50-59: 17.0% - (4 of 23 people)
  • 60+: 18.0% - (2 of 11 people)
Morphine Sulfate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 57.0% - (4 of 7 people)
  • 30-39: 47.0% - (8 of 17 people)
  • 40-49: 29.0% - (5 of 17 people)
  • 50-59: 26.0% - (6 of 23 people)
  • 60+: 28.0% - (4 of 14 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • confusional state
  • malaise
  • pyrexia
  • dizziness
  • nausea
  • pain
  • drug ineffective
  • renal failure acute
  • constipation
1 - 6 months:
  • oedema peripheral
  • pain
  • somnolence
  • drug ineffective
  • confusional state
  • renal failure acute
  • respiratory failure
  • dizziness
  • insomnia
  • dry mouth
6 - 12 months:
  • drug ineffective
  • fall
  • oedema peripheral
  • renal failure acute
  • sepsis
  • cardiac failure
  • disorientation
  • dyspnoea
  • pain
  • pyrexia
1 - 2 years:
  • pain
  • back pain
  • somnolence
  • suicide attempt
  • cerebrovascular accident
  • chest pain
  • drug ineffective
  • dyspnoea
  • fluid retention
  • gait disturbance
2 - 5 years:
  • depression
  • fatigue
  • chronic fatigue syndrome
  • nausea
  • pain
  • suicidal ideation
  • weakness
  • drug dependence
  • fall
  • insomnia
5 - 10 years:
  • dry mouth
  • blood cholesterol increased
  • erectile dysfunction
  • fibromyalgia
  • memory impairment
  • antiphospholipid syndrome
  • arthritis
  • back pain - low
  • compulsive shopping
  • confusion
10+ years:
  • back pain - low
  • leg pain
  • body height decreased
  • dehydration
  • depressed level of consciousness
  • drug ineffective
  • hyperhidrosis
  • hypokinesia
  • limb injury
  • musculoskeletal disorder
not specified:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • back pain
  • dizziness
  • fatigue
  • fall
  • pyrexia
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • dizziness
  • fall
  • dyspnoea
  • drug ineffective
  • back pain
  • fatigue
  • somnolence
male:
  • pain
  • anxiety
  • dyspnoea
  • back pain
  • somnolence
  • pyrexia
  • confusional state
  • asthenia
  • fatigue
  • oedema peripheral

Most common drug interactions by age *:

0-1:
  • drug withdrawal syndrome
  • foetal exposure during pregnancy
2-9:
  • arthralgia
  • bone pain
  • sepsis
  • tumour lysis syndrome
  • respiratory failure
  • pneumonia
  • renal failure
  • disease progression
  • neutropenia
  • atrioventricular block second degree
10-19:
  • arthralgia
  • balance disorder
  • brain oedema
  • disseminated intravascular coagulation
  • drug rash with eosinophilia and systemic symptoms
  • multi-organ failure
  • pyrexia
  • rash
  • fall
  • general physical health deterioration
20-29:
  • pain
  • nausea
  • dyspnoea
  • hypertension
  • influenza like illness
  • pyrexia
  • urinary tract infection
  • vomiting
  • abdominal pain upper
  • bronchitis
30-39:
  • pain
  • fatigue
  • oedema peripheral
  • nausea
  • somnolence
  • headache
  • depression
  • abdominal pain
  • arthralgia
  • drug ineffective
40-49:
  • pain
  • anxiety
  • dyspnoea
  • pneumonia
  • back pain
  • nausea
  • fatigue
  • pyrexia
  • somnolence
  • insomnia
50-59:
  • pain
  • anxiety
  • pyrexia
  • dyspnoea
  • dizziness
  • arthralgia
  • hypoaesthesia
  • nausea
  • back pain
  • bone disorder
60+:
  • pain
  • confusional state
  • anxiety
  • back pain
  • dyspnoea
  • fall
  • somnolence
  • nausea
  • osteoarthritis
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Morphine sulfate (morphine sulfate) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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