Review: taking Lyrica and Tylenol together


Summary

Drug interactions are reported among people who take Lyrica and Tylenol together. This review analyzes the effectiveness and drug interactions between Lyrica and Tylenol. It is created by eHealthMe based on reports of 5,370 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 121,583 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 81,872 users)

On Sep, 14, 2016

5,370 people who take Lyrica, Tylenol are studied.


Number of reports submitted per year:

Lyrica and Tylenol drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 37.0% - (3 of 8 people)
  • 1 - 6 months: 37.0% - (3 of 8 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 15.0% - (2 of 13 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Tylenol:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 0.0% - (0 of 5 people)
  • 5 - 10 years: 14.0% - (1 of 7 people)
  • 10+ years: 33.0% - (3 of 9 people)
  • not specified: 75.0% - (3 of 4 people)

Drug effectiveness by gender:

Lyrica:
  • female: 25.0% - (9 of 35 people)
  • male: 50.0% - (4 of 8 people)
Tylenol:
  • female: 15.0% - (5 of 33 people)
  • male: 40.0% - (4 of 10 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 33.0% - (4 of 12 people)
  • 50-59: 36.0% - (4 of 11 people)
  • 60+: 30.0% - (3 of 10 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 33.0% - (3 of 9 people)
  • 40-49: 0.0% - (0 of 11 people)
  • 50-59: 27.0% - (3 of 11 people)
  • 60+: 20.0% - (2 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • dizziness
  • pyrexia
  • drug ineffective
  • nausea
  • somnolence
  • vomiting
  • malaise
  • asthenia
  • fatigue
1 - 6 months:
  • malaise
  • nausea
  • confusional state
  • decreased appetite
  • fall
  • pain
  • dizziness
  • aphasia
  • insomnia
  • vomiting
6 - 12 months:
  • fatigue
  • feeling abnormal
  • nausea
  • dizziness
  • haemoptysis
  • vision blurred
  • weight increased
  • asthenia
  • muscle spasms
  • somnolence
1 - 2 years:
  • fall
  • dizziness
  • syncope
  • visual impairment
  • diplopia
  • vision blurred
  • abasia
  • drug ineffective
  • hallucination
  • myalgia
2 - 5 years:
  • headache
  • fibromyalgia
  • depression
  • fatigue - chronic
  • hypothyroidism
  • menopause
  • temporomandibular joint syndrome
  • pain
  • oedema peripheral
  • asthenia
5 - 10 years:
  • pain
  • fatigue
  • gait disturbance
  • hair loss
  • lightheadedness - dizzy
  • lip blister
  • malaise
  • memory loss
  • tingling and numbness
  • tongue - patchy
10+ years:
  • cognitive disorder
  • aphasia
  • chronic fatigue syndrome
  • confusion
  • depression
  • diabetes mellitus inadequate control
  • dysarthria
  • dyskinesia
  • encephalopathy
  • fall
not specified:
  • pain
  • nausea
  • drug ineffective
  • fatigue
  • dizziness
  • headache
  • dyspnoea
  • fall
  • asthenia
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • dizziness
  • headache
  • drug ineffective
  • dyspnoea
  • fall
  • somnolence
  • pain in extremity
male:
  • pain
  • drug ineffective
  • fall
  • fatigue
  • asthenia
  • anxiety
  • malaise
  • nausea
  • somnolence
  • gait disturbance

Most common drug interactions by age *:

0-1:
  • cerebral haemorrhage
  • cerebral ventricle dilatation
  • hydrocephalus
  • hyperbilirubinaemia neonatal
  • hypotonia neonatal
  • maternal exposure during pregnancy
  • ovarian cyst
  • patent ductus arteriosus
  • premature baby
  • blood urine present
2-9:
  • pancreatitis
  • bone giant cell tumour
  • abdominal pain upper
  • cholecystitis
  • cough
  • faeces pale
  • hepatic pain
  • hepatitis
  • hepatomegaly
  • hypophagia
10-19:
  • pyrexia
  • paraesthesia
  • vomiting
  • arthralgia
  • balance disorder
  • chills
  • heart rate increased
  • device related infection
  • brain oedema
  • disseminated intravascular coagulation
20-29:
  • nausea
  • fatigue
  • dyspnoea
  • headache
  • vomiting
  • cardiac failure congestive
  • urinary tract infection
  • dizziness
  • abdominal pain
  • multi-organ failure
30-39:
  • pain
  • nausea
  • dizziness
  • fatigue
  • dyspnoea
  • headache
  • abdominal pain
  • vomiting
  • malaise
  • paraesthesia
40-49:
  • pain
  • fatigue
  • drug ineffective
  • pneumonia
  • anxiety
  • nausea
  • headache
  • depression
  • malaise
  • back pain
50-59:
  • pain
  • headache
  • drug ineffective
  • nausea
  • fatigue
  • pain in extremity
  • vomiting
  • pyrexia
  • arthralgia
  • weight decreased
60+:
  • pain
  • fall
  • drug ineffective
  • nausea
  • dyspnoea
  • confusional state
  • somnolence
  • dizziness
  • asthenia
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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