Review: taking Lyrica and Tylenol together


Summary

Drug interactions are reported among people who take Lyrica and Tylenol together. This review analyzes the effectiveness and drug interactions between Lyrica and Tylenol. It is created by eHealthMe based on reports of 3,822 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 82,030 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 61,244 users)

On Aug, 23, 2016

3,822 people who take Lyrica, Tylenol are studied.


Number of reports submitted per year:

Lyrica and Tylenol drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 37.0% - (3 of 8 people)
  • 1 - 6 months: 37.0% - (3 of 8 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 15.0% - (2 of 13 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Tylenol:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 25.0% - (1 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 6 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 0.0% - (0 of 5 people)
  • 5 - 10 years: 14.0% - (1 of 7 people)
  • 10+ years: 33.0% - (3 of 9 people)
  • not specified: 75.0% - (3 of 4 people)

Drug effectiveness by gender:

Lyrica:
  • female: 25.0% - (9 of 35 people)
  • male: 50.0% - (4 of 8 people)
Tylenol:
  • female: 15.0% - (5 of 33 people)
  • male: 40.0% - (4 of 10 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 33.0% - (4 of 12 people)
  • 50-59: 36.0% - (4 of 11 people)
  • 60+: 30.0% - (3 of 10 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 33.0% - (3 of 9 people)
  • 40-49: 0.0% - (0 of 11 people)
  • 50-59: 27.0% - (3 of 11 people)
  • 60+: 20.0% - (2 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • dizziness
  • somnolence
  • drug ineffective
  • fatigue
  • pyrexia
  • vomiting
  • asthenia
  • malaise
  • oedema peripheral
1 - 6 months:
  • decreased appetite
  • malaise
  • fall
  • pain
  • aphasia
  • confusional state
  • insomnia
  • nausea
  • sleep apnoea syndrome
  • fatigue
6 - 12 months:
  • fatigue
  • feeling abnormal
  • dizziness
  • haemoptysis
  • nausea
  • asthenia
  • somnolence
  • vision blurred
  • weight increased
  • muscle spasms
1 - 2 years:
  • fall
  • syncope
  • abasia
  • hallucination
  • myalgia
  • aphasia
  • circulatory collapse
  • depression
  • feeling abnormal
  • muscle enzyme increased
2 - 5 years:
  • headache
  • fibromyalgia
  • depression
  • fatigue - chronic
  • hypothyroidism
  • menopause
  • temporomandibular joint syndrome
  • oedema peripheral
  • asthenia
  • pain
5 - 10 years:
  • fatigue
  • hair loss
  • lightheadedness - dizzy
  • lip blister
  • malaise
  • memory loss
  • pain
  • tingling and numbness
  • tongue - patchy
  • acute hepatic failure
10+ years:
  • cognitive disorder
  • aphasia
  • chronic fatigue syndrome
  • confusion
  • depression
  • diabetes mellitus inadequate control
  • dysarthria
  • dyskinesia
  • encephalopathy
  • fall
not specified:
  • pain
  • nausea
  • dyspnoea
  • fatigue
  • fall
  • dizziness
  • headache
  • anxiety
  • drug ineffective
  • asthenia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • dizziness
  • dyspnoea
  • headache
  • asthenia
  • fall
  • drug ineffective
  • depression
male:
  • pain
  • fall
  • drug ineffective
  • renal failure acute
  • anxiety
  • anaemia
  • nausea
  • abdominal pain
  • pain in extremity
  • vomiting

Most common drug interactions by age *:

0-1:
  • blood urine present
  • dyspnoea
  • gout
  • iron deficiency anaemia
  • metabolic disorder
  • myopathy
  • renal failure acute
  • rhabdomyolysis
2-9:
  • bone giant cell tumour
10-19:
  • pyrexia
  • paraesthesia
  • vomiting
  • balance disorder
  • chills
  • device related infection
  • arthralgia
  • brain oedema
  • disseminated intravascular coagulation
  • drug rash with eosinophilia and systemic symptoms
20-29:
  • dyspnoea
  • cardiac failure congestive
  • nausea
  • fatigue
  • multi-organ failure
  • insomnia
  • hypertension
  • vomiting
  • back pain
  • pain
30-39:
  • pain
  • nausea
  • dyspnoea
  • dizziness
  • headache
  • fatigue
  • abdominal pain
  • depression
  • vomiting
  • paraesthesia
40-49:
  • pain
  • fatigue
  • drug ineffective
  • headache
  • back pain
  • pneumonia
  • vision blurred
  • nausea
  • anxiety
  • dizziness
50-59:
  • pain
  • headache
  • nausea
  • vomiting
  • pain in extremity
  • drug ineffective
  • pyrexia
  • asthenia
  • fatigue
  • depression
60+:
  • pain
  • fall
  • nausea
  • dyspnoea
  • confusional state
  • somnolence
  • fatigue
  • asthenia
  • dizziness
  • dehydration

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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