Review: taking Lyrica and Tylenol together


Summary

Drug interactions are reported among people who take Lyrica and Tylenol together. This review analyzes the effectiveness and drug interactions between Lyrica and Tylenol. It is created by eHealthMe based on reports of 2,858 people who take the same drugs from FDA and social media, and is updated regularly.

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Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 64,294 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 53,038 users)

On Jul, 29, 2016

2,858 people who take Lyrica, Tylenol are studied.


Number of reports submitted per year:

Lyrica and Tylenol drug interactions.

Drug effectiveness over time:

Lyrica:
  • < 1 month: 37.0% - (3 of 8 people)
  • 1 - 6 months: 38.0% - (5 of 13 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 12.0% - (2 of 16 people)
  • 2 - 5 years: 29.0% - (5 of 17 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Tylenol:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 7 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 0.0% - (0 of 17 people)
  • 5 - 10 years: 12.0% - (1 of 8 people)
  • 10+ years: 30.0% - (4 of 13 people)
  • not specified: 75.0% - (3 of 4 people)

Drug effectiveness by gender:

Lyrica:
  • female: 24.0% - (13 of 53 people)
  • male: 50.0% - (4 of 8 people)
Tylenol:
  • female: 11.0% - (6 of 51 people)
  • male: 36.0% - (4 of 11 people)

Drug effectiveness by age:

Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 22.0% - (2 of 9 people)
  • 40-49: 33.0% - (6 of 18 people)
  • 50-59: 22.0% - (5 of 22 people)
  • 60+: 30.0% - (3 of 10 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 40.0% - (4 of 10 people)
  • 40-49: 0.0% - (0 of 17 people)
  • 50-59: 13.0% - (3 of 22 people)
  • 60+: 18.0% - (2 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • dizziness
  • somnolence
  • pyrexia
  • fatigue
  • oedema peripheral
  • asthenia
  • drug ineffective
  • erythema
  • malaise
1 - 6 months:
  • malaise
  • decreased appetite
  • pain
  • aphasia
  • fall
  • confusional state
  • insomnia
  • fatigue
  • nausea
  • sleep apnoea syndrome
6 - 12 months:
  • feeling abnormal
  • dizziness
  • haemoptysis
  • asthenia
  • fatigue
  • nausea
  • weight increased
  • vision blurred
  • back injury
  • communication disorder
1 - 2 years:
  • fall
  • syncope
  • myalgia
  • abasia
  • circulatory collapse
  • muscle enzyme increased
  • muscular weakness
  • oedema peripheral
  • stent placement
  • urticaria
2 - 5 years:
  • headache
  • fibromyalgia
  • fatigue - chronic
  • hypothyroidism
  • menopause
  • temporomandibular joint syndrome
  • oedema peripheral
  • depression
  • agranulocytosis
  • asthenia
5 - 10 years:
  • fatigue
  • hair loss
  • lightheadedness - dizzy
  • lip blister
  • memory loss
  • tingling and numbness
  • tongue - patchy
  • balance disorder
  • depression suicidal
  • drowsiness
10+ years:
  • aphasia
  • chronic fatigue syndrome
  • cognitive disorder
  • confusion
  • fall
  • sleep apnea
  • suicidal ideation
  • sweating increased
  • fatigue
  • hair loss
not specified:
  • pain
  • nausea
  • dizziness
  • dyspnoea
  • fatigue
  • anxiety
  • fall
  • somnolence
  • asthenia
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • dizziness
  • fatigue
  • dyspnoea
  • headache
  • asthenia
  • oedema peripheral
  • fall
  • somnolence
male:
  • pain
  • renal failure acute
  • anaemia
  • anxiety
  • abdominal pain
  • vision blurred
  • fall
  • neuropathy peripheral
  • vomiting
  • nausea

Most common drug interactions by age *:

0-1:
  • blood urine present
  • dyspnoea
  • gout
  • iron deficiency anaemia
  • metabolic disorder
  • myopathy
  • renal failure acute
  • rhabdomyolysis
10-19:
  • pyrexia
  • paraesthesia
  • vomiting
  • balance disorder
  • device related infection
  • arthralgia
  • brain oedema
  • disseminated intravascular coagulation
  • drug rash with eosinophilia and systemic symptoms
  • heart rate increased
20-29:
  • dyspnoea
  • cardiac failure congestive
  • multi-organ failure
  • nausea
  • hypertension
  • back pain
  • bronchitis
  • fatigue
  • influenza like illness
  • urinary tract infection
30-39:
  • nausea
  • dyspnoea
  • dizziness
  • pain
  • fatigue
  • headache
  • depression
  • paraesthesia
  • suicidal ideation
  • neuropathy peripheral
40-49:
  • pain
  • fatigue
  • headache
  • back pain
  • dizziness
  • drug ineffective
  • anaemia
  • diplopia
  • vision blurred
  • pneumonia
50-59:
  • pain
  • headache
  • nausea
  • asthenia
  • weight decreased
  • oedema peripheral
  • pyrexia
  • depression
  • dry mouth
  • vomiting
60+:
  • pain
  • fall
  • confusional state
  • nausea
  • dyspnoea
  • renal failure acute
  • dehydration
  • somnolence
  • asthenia
  • abdominal pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Lyrica (pregabalin) is often used to treat fibromyalgia. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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