Macrobid and Methotrexate drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Macrobid and Methotrexate together. This review analyzes the effectiveness and drug interactions between Macrobid and Methotrexate. It is created by eHealthMe based on reports of 194 people who take the same drugs from FDA, and is updated regularly.

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If you take Macrobid and Methotrexate, find out what symptoms you could have in 1 year or longer.

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Macrobid

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. (latest outcomes from Macrobid 4,915 users)

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,557 users)

On Feb, 02, 2017

194 people who take Macrobid, Methotrexate are studied.


Number of reports submitted per year:

Macrobid and Methotrexate drug interactions.

Most common drug interactions over time *:

< 1 month:
  • swelling face
  • urinary tract infection
  • acute respiratory failure
  • atrial fibrillation
  • death
  • diverticular perforation
  • drug hypersensitivity
  • eczema
  • encephalopathy
  • femur fracture
1 - 6 months:
  • urinary tract infection
  • acute respiratory failure
  • adverse event
  • atrial fibrillation
  • conjunctivitis
  • death
  • diverticular perforation
  • drug hypersensitivity
  • encephalopathy
  • femur fracture
6 - 12 months:
  • adverse event
  • conjunctivitis
  • nodule
  • pneumonia
  • swelling
  • visual impairment
  • overlap syndrome
1 - 2 years:
  • adverse event
  • conjunctivitis
  • nodule
  • pneumonia
  • swelling
  • visual impairment
  • bronchopneumonia
  • chest discomfort
  • coma
  • dizziness
2 - 5 years:
  • bone marrow failure
  • adverse event
  • conjunctivitis
  • nodule
  • overlap syndrome
  • pneumonia
  • swelling
  • visual impairment
5 - 10 years:
  • activities of daily living impaired
  • anxiety
  • asthenia
  • bladder disorder
  • chorea
  • confusional state
  • disorientation
  • dysgraphia
  • dyskinesia
  • dysphagia
10+ years:
  • arthralgia
  • cough
  • meningitis cryptococcal
  • nasal congestion
  • pulmonary fibrosis
  • bacteria urine identified
  • blood culture positive
  • blood urine present
  • chest x-ray abnormal
  • fungus culture positive
not specified:
  • nausea
  • headache
  • pain
  • dizziness
  • fatigue
  • dyspnoea
  • urinary tract infection
  • pain in extremity
  • drug ineffective
  • arthralgia

Most common drug interactions by gender *:

female:
  • nausea
  • headache
  • pain
  • urinary tract infection
  • dizziness
  • dyspnoea
  • swelling face
  • arthralgia
  • fatigue
  • pain in extremity
male:
  • drug ineffective
  • epistaxis
  • bone marrow failure
  • constipation
  • fatigue
  • malaise
  • pneumonia
  • asthenia
  • blood alkaline phosphatase increased
  • bundle branch block right

Most common drug interactions by age *:

2-9:
  • pruritus
  • scar
  • acute sinusitis
  • anaemia
  • angiopathy
  • anhedonia
  • anxiety
  • aortic arteriosclerosis
  • application site dryness
  • application site irritation
10-19:
  • ventricular septal defect
  • colitis
20-29:
  • colitis ulcerative
  • fall
  • femur fracture
  • foot fracture
  • hepatic cirrhosis
  • joint dislocation
  • joint injury
  • lower limb fracture
  • nasopharyngitis
  • osteoporosis
30-39:
  • diarrhoea
  • abdominal pain
  • arthralgia
  • back pain
  • cellulitis
  • constipation
  • drug ineffective
  • feeling abnormal
  • feeling cold
  • fungal infection
40-49:
  • arthralgia
  • pain
  • emotional distress
  • general physical health deterioration
  • abdominal pain
  • animal bite
  • benign neoplasm of thyroid gland
  • bone disorder
  • colon neoplasm
  • decreased interest
50-59:
  • nausea
  • headache
  • dizziness
  • pain in extremity
  • injection site bruising
  • fatigue
  • abdominal pain upper
  • malaise
  • pain
  • visual impairment
60+:
  • urinary tract infection
  • nausea
  • headache
  • swelling face
  • urosepsis
  • arthralgia
  • death
  • drug hypersensitivity
  • pain
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Macrobid and Methotrexate?

Interactions between Macrobid and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Methotrexate and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) is often used to treat urinary tract infection. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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