Review: taking Melatonin and Clonazepam together


Summary

Drug interactions are reported among people who take Melatonin and Clonazepam together. This review analyzes the effectiveness and drug interactions between Melatonin and Clonazepam. It is created by eHealthMe based on reports of 262 people who take the same drugs from FDA and social media, and is updated regularly.

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Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 3,072 users)

Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 39,945 users)

On Jul, 23, 2016

262 people who take Melatonin, Clonazepam are studied.


Number of reports submitted per year:

Melatonin and Clonazepam drug interactions.

Drug effectiveness over time:

Melatonin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 33.0% - (2 of 6 people)
  • 6 - 12 months: 55.0% - (5 of 9 people)
  • 1 - 2 years: 18.0% - (3 of 16 people)
  • 2 - 5 years: 30.0% - (6 of 20 people)
  • 5 - 10 years: 77.0% - (7 of 9 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Clonazepam:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 13.0% - (2 of 15 people)
  • 6 - 12 months: 80.0% - (4 of 5 people)
  • 1 - 2 years: 100.0% - (9 of 9 people)
  • 2 - 5 years: 36.0% - (4 of 11 people)
  • 5 - 10 years: 80.0% - (12 of 15 people)
  • 10+ years: 87.0% - (7 of 8 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Melatonin:
  • female: 30.0% - (16 of 52 people)
  • male: 70.0% - (7 of 10 people)
Clonazepam:
  • female: 59.0% - (31 of 52 people)
  • male: 66.0% - (8 of 12 people)

Drug effectiveness by age:

Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 28.0% - (2 of 7 people)
  • 30-39: 50.0% - (6 of 12 people)
  • 40-49: 22.0% - (4 of 18 people)
  • 50-59: 60.0% - (6 of 10 people)
  • 60+: 25.0% - (3 of 12 people)
Clonazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 66.0% - (2 of 3 people)
  • 20-29: 14.0% - (1 of 7 people)
  • 30-39: 83.0% - (10 of 12 people)
  • 40-49: 16.0% - (3 of 18 people)
  • 50-59: 100.0% - (10 of 10 people)
  • 60+: 92.0% - (13 of 14 people)

Most common drug interactions over time *:

< 1 month:
  • accidental exposure
  • confusional state
  • depressed level of consciousness
  • incontinence
  • lethargy
  • body temperature increased
  • dermatitis exfoliative
  • drug rash with eosinophilia and systemic symptoms
  • enanthema
  • eosinophilia
1 - 6 months:
  • arthritis
  • pseudoporphyria
  • anxiety
  • anxiety disorder
  • constipation
  • depression
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
6 - 12 months:
  • fatigue
  • depression
  • frequent or urgent urination
  • hyperlipidemia
  • hypertension
  • insomnia
  • restless leg syndrome
  • seroma
  • tachycardia
  • type 2 diabetes
1 - 2 years:
  • insomnia
  • constipation aggravated
  • heat intolerance
  • dark circles under eyes
  • insomnia related to another mental condition
  • movement - uncoordinated
  • nightmares - repeated
  • restless leg syndrome
  • supraventricular tachycardia
  • teeth grinding and clenching
2 - 5 years:
  • arthritis
  • pseudoporphyria
  • depression
  • anxiety
  • anxiety disorder
  • constipation
  • depression suicidal
  • facial nerve disorder
  • facial nerve palsy
  • facial pain
5 - 10 years:
  • inflammation localised
  • arthritis
  • fear of weight gain
  • hearing loss
  • bone and joint pain
  • drug-induced erectile dysfunction
  • dry skin
  • earache
  • hallucinations, mixed
  • herpes simplex
10+ years:
  • dark circles under eyes
  • insomnia related to another mental condition
  • movement - uncoordinated
  • nightmares - repeated
  • supraventricular tachycardia
  • teeth grinding and clenching
  • vision blurred
  • diarrhoea
  • skin blushing/flushing
  • aortic valve stenosis
not specified:
  • fatigue
  • nausea
  • drug ineffective
  • insomnia
  • pain
  • pain in extremity
  • chest pain
  • influenza like illness
  • anxiety
  • visual impairment

Most common drug interactions by gender *:

female:
  • fatigue
  • nausea
  • drug ineffective
  • pain in extremity
  • pain
  • insomnia
  • influenza like illness
  • chest pain
  • visual impairment
  • anxiety
male:
  • insomnia
  • anxiety
  • agitation
  • myelodysplastic syndrome
  • restlessness
  • somnolence
  • akathisia
  • confusional state
  • drug ineffective
  • fall

Most common drug interactions by age *:

0-1:
  • cough
  • feeling cold
  • gastroenteritis
  • pneumonia
  • pyrexia
  • respiratory tract congestion
  • somnolence
2-9:
  • convulsion
  • hypertonia
  • muscle rigidity
  • status epilepticus
10-19:
  • convulsion
  • anticonvulsant drug level decreased
  • death
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • asphyxia
  • depressed level of consciousness
  • gamma-glutamyltransferase increased
  • lightheadedness - fainting
  • mental status changes
20-29:
  • acute prerenal failure
  • anger
  • back pain
  • bone and joint pain
  • cardiac arrest
  • circulatory collapse
  • coagulopathy
  • compartment syndrome
  • depressed mood
  • dissociation
30-39:
  • oedema peripheral
  • pain
  • fatigue
  • swelling face
  • cough
  • bronchitis
  • chest pain
  • decreased appetite
  • headache
  • inflammation localised
40-49:
  • arthritis
  • pseudoporphyria
  • fatigue
  • anxiety
  • constipation
  • nausea
  • depression
  • vomiting
  • abdominal pain
  • anxiety disorder
50-59:
  • insomnia
  • confusional state
  • drug ineffective
  • incontinence
  • lethargy
  • unresponsive to stimuli
  • accidental exposure
  • anxiety
  • restlessness
  • pain
60+:
  • insomnia
  • drug ineffective
  • fall
  • influenza like illness
  • visual impairment
  • fatigue
  • pain in extremity
  • arthralgia
  • breast cancer in situ
  • fibrocystic breast disease

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Melatonin (melatonin) is often used to treat insomnia. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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