Review: taking Melatonin and Levothyroxine sodium together


Summary

Drug interactions are reported among people who take Melatonin and Levothyroxine sodium together. This review analyzes the effectiveness and drug interactions between Melatonin and Levothyroxine sodium. It is created by eHealthMe based on reports of 681 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Melatonin and Levothyroxine sodium >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 4,547 users)

Levothyroxine Sodium

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Levothyroxine sodium 68,990 users)

On Aug, 25, 2016

681 people who take Melatonin, Levothyroxine Sodium are studied.


Number of reports submitted per year:

Melatonin and Levothyroxine sodium drug interactions.

Drug effectiveness over time:

Melatonin:
  • < 1 month: 0.0% - (0 of 5 people)
  • 1 - 6 months: 21.0% - (3 of 14 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 27.0% - (3 of 11 people)
  • 2 - 5 years: 53.0% - (7 of 13 people)
  • 5 - 10 years: 33.0% - (2 of 6 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Levothyroxine Sodium:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 14.0% - (1 of 7 people)
  • 2 - 5 years: 50.0% - (7 of 14 people)
  • 5 - 10 years: 50.0% - (5 of 10 people)
  • 10+ years: 70.0% - (17 of 24 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Melatonin:
  • female: 30.0% - (15 of 49 people)
  • male: 14.0% - (1 of 7 people)
Levothyroxine Sodium:
  • female: 54.0% - (29 of 53 people)
  • male: 50.0% - (4 of 8 people)

Drug effectiveness by age:

Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 16.0% - (2 of 12 people)
  • 50-59: 46.0% - (7 of 15 people)
  • 60+: 26.0% - (6 of 23 people)
Levothyroxine Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 100.0% - (3 of 3 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 60.0% - (9 of 15 people)
  • 50-59: 46.0% - (7 of 15 people)
  • 60+: 48.0% - (12 of 25 people)

Most common drug interactions over time *:

< 1 month:
  • nosebleed
  • antepartum haemorrhage
  • nasopharyngitis
  • pruritus
  • rash maculo-papular
  • subchorionic haemorrhage
  • vitamin d deficiency
  • abscess intestinal
  • arrhythmia
  • cardiovascular disorder
1 - 6 months:
  • bloating
  • weight gain
  • diarrhoea
  • alopecia
  • antepartum haemorrhage
  • change of bowel habit
  • constipation
  • flatulence
  • irritable bowel syndrome
  • anxiety
6 - 12 months:
  • alopecia
  • change of bowel habit
  • constipation
  • cough
  • diarrhoea
  • flatulence
  • irritable bowel syndrome
  • bipolar
  • blood thyroid stimulating hormone increased
  • cavities - tooth
1 - 2 years:
  • constipation aggravated
  • heat intolerance
  • insomnia
  • dark circles under eyes
  • insomnia related to another mental condition
  • loss of taste
  • movement - uncoordinated
  • nightmares - repeated
  • supraventricular tachycardia
  • teeth grinding and clenching
2 - 5 years:
  • nosebleed
  • dark circles under eyes
  • insomnia related to another mental condition
  • loss of taste
  • movement - uncoordinated
  • nightmares - repeated
  • supraventricular tachycardia
  • teeth grinding and clenching
  • vision blurred
  • cough
5 - 10 years:
  • bone and joint pain
  • dry skin
  • earache
  • herpes simplex
  • itchiness
  • muscle pain
  • muscle spasms
  • skin blushing/flushing
  • stomach upset
  • sweating - excessive
10+ years:
  • insomnia
  • bloating
  • weight gain
  • constipation aggravated
  • depression
  • heat intolerance
  • frequent headaches
  • joint dislocation
  • postnasal drip
  • stomach upset
not specified:
  • nausea
  • fatigue
  • headache
  • fall
  • pain
  • drug ineffective
  • insomnia
  • dyspnoea
  • dizziness
  • injection site pain

Most common drug interactions by gender *:

female:
  • nausea
  • headache
  • fatigue
  • insomnia
  • pain
  • fall
  • depression
  • drug ineffective
  • dyspnoea
  • injection site pain
male:
  • fatigue
  • drug ineffective
  • fall
  • myelodysplastic syndrome
  • nausea
  • nosebleed
  • renal failure acute
  • cardiac failure congestive
  • respiratory failure
  • asthenia

Most common drug interactions by age *:

0-1:
  • respiratory distress
2-9:
  • abdominal pain
  • arterial occlusive disease
  • cerebrovascular accident
  • dehydration
  • diarrhoea
  • pulmonary oedema
  • radiation injury
  • skin hypertrophy
  • vasculitis
  • activated partial thromboplastin time prolonged
10-19:
  • anal fistula
  • crohn's disease
  • headache
  • confusional state
  • convulsion
  • haemorrhagic cerebral infarction
  • perirectal abscess
  • pneumonia aspiration
  • spastic diplegia
  • transverse sinus thrombosis
20-29:
  • gastrooesophageal reflux disease
  • hypothyroidism
  • depression
  • back pain
  • bipolar i disorder
  • blood cholesterol increased
  • chronic obstructive pulmonary disease
  • diabetes mellitus
  • diarrhoea
  • diplopia
30-39:
  • headache
  • convulsion
  • cough
  • dark circles under eyes
  • epilepsy
  • injury
  • insomnia related to another mental condition
  • movement - uncoordinated
  • nausea
  • nightmares - repeated
40-49:
  • fatigue
  • weight increased
  • pruritus
  • drug ineffective
  • bloating
  • decreased appetite
  • weight gain
  • dizziness
  • weight decreased
  • depression
50-59:
  • dyspnoea
  • drug ineffective
  • fatigue
  • nausea
  • headache
  • pain in extremity
  • insomnia
  • gastrooesophageal reflux disease
  • injection site pain
  • rash
60+:
  • fatigue
  • nausea
  • headache
  • fall
  • depression
  • pain
  • insomnia
  • dyspnoea
  • hypertension
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Melatonin and Levothyroxine sodium?

Can you answer these questions?

More questions for: Melatonin, Levothyroxine sodium

You may be interested in these reviews

More reviews for: Melatonin, Levothyroxine sodium

On eHealthMe, Melatonin (melatonin) is often used to treat insomnia. Levothyroxine sodium (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.