Review: taking Metformin hydrochloride and Nucynta together


Summary

Drug interactions are reported among people who take Metformin hydrochloride and Nucynta together. This review analyzes the effectiveness and drug interactions between Metformin hydrochloride and Nucynta. It is created by eHealthMe based on reports of 75 people who take the same drugs from FDA and social media, and is updated regularly.

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Metformin Hydrochloride

Metformin hydrochloride has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin hydrochloride 14,249 users)

Nucynta

Nucynta has active ingredients of tapentadol hydrochloride. It is often used in pain. (latest outcomes from Nucynta 2,173 users)

On Aug, 25, 2016

75 people who take Metformin Hydrochloride, Nucynta are studied.


Number of reports submitted per year:

Metformin hydrochloride and Nucynta drug interactions.

Drug effectiveness over time:

Metformin Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Nucynta:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Metformin Hydrochloride:
  • female: 66.0% - (2 of 3 people)
  • male: 0.0% - (0 of 2 people)
Nucynta:
  • female: 66.0% - (2 of 3 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Metformin Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 2 people)
Nucynta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • dyspnoea
  • asthenopia
  • back pain
  • feeling abnormal
  • feeling drunk
  • gait disturbance
  • abdominal discomfort
  • anxiety
  • application site ulcer
  • asthenia
1 - 6 months:
  • fall
  • vertigo
  • hyperglycaemia
  • hypertensive crisis
  • leukocytosis
  • spinal fracture
  • burning mouth syndrome
6 - 12 months:
  • aggression
  • burning mouth syndrome
  • convulsion
  • dysarthria
  • dyskinesia
  • incoherent
  • pain
  • sweating - excessive
1 - 2 years:
  • sweating - excessive
2 - 5 years:
  • renal impairment
  • anaemia
  • pancytopenia
5 - 10 years:
  • anxiety
  • back pain
  • headache
  • impaired gastric emptying
  • weight gain
10+ years:
  • anaemia
  • pancytopenia
  • renal impairment
not specified:
  • gastrointestinal disorder
  • dyspnoea
  • chest pain
  • dizziness
  • vision blurred
  • hyperhidrosis
  • dehydration
  • presyncope
  • confusional state
  • fall

Most common drug interactions by gender *:

female:
  • gastrointestinal disorder
  • dehydration
  • fall
  • diarrhoea
  • vomiting
  • chest pain
  • flatulence
  • malaise
  • presyncope
  • abdominal discomfort
male:
  • dyspnoea
  • chest pain
  • dizziness
  • vision blurred
  • hyperhidrosis
  • confusional state
  • back pain
  • drug screen positive
  • tremor
  • abnormal behaviour

Most common drug interactions by age *:

20-29:
  • aggression
  • convulsion
  • dysarthria
  • dyskinesia
  • incoherent
  • pain
30-39:
  • deep vein thrombosis
  • injury
  • anxiety
  • back pain
  • headache
  • impaired gastric emptying
  • malaise
  • road traffic accident
  • weight gain
40-49:
  • pain
  • back pain
  • hyperglycaemia
  • hyperhidrosis
  • nausea
  • vomiting
  • weight decreased
  • abdominal discomfort
  • abdominal pain
  • anhedonia
50-59:
  • confusional state
  • asthenopia
  • delirium
  • dka
  • dyspnoea
  • feeling abnormal
  • feeling drunk
  • gait disturbance
  • loss of consciousness
  • retrograde amnesia
60+:
  • dizziness
  • dehydration
  • hyperhidrosis
  • vision blurred
  • presyncope
  • fall
  • vomiting
  • gastrointestinal disorder
  • chest pain
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Metformin hydrochloride (metformin hydrochloride) is often used to treat diabetes. Nucynta (tapentadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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