Metformin and Aspirin drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Metformin and Aspirin together. This review analyzes the effectiveness and drug interactions between Metformin and Aspirin. It is created by eHealthMe based on reports of 35,037 people who take the same drugs from FDA, and is updated regularly.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,363 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in blood clots. (latest outcomes from Aspirin 283,041 users)

On Feb, 01, 2017

35,037 people who take Metformin, Aspirin are studied.


Number of reports submitted per year:

Metformin and Aspirin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • diarrhoea
  • vomiting
  • renal failure acute
  • hypoglycaemia
  • headache
  • hypotension
  • overdose
  • nausea
  • hyponatraemia
  • dehydration
1 - 6 months:
  • asthenia
  • renal failure acute
  • malaise
  • nausea
  • confusional state
  • hypoglycaemia
  • lactic acidosis
  • pain
  • syncope
  • pneumonia
6 - 12 months:
  • lactic acidosis
  • hypoglycaemia
  • encephalopathy
  • nausea
  • renal failure acute
  • hepatic failure
  • hepatitis cholestatic
  • duodenal ulcer
  • jaundice cholestatic
  • hepatic neoplasm malignant
1 - 2 years:
  • renal failure acute
  • hypoglycaemia
  • lactic acidosis
  • vomiting
  • nausea
  • rhabdomyolysis
  • hyperkalaemia
  • myocardial infarction
  • pain
  • atrial fibrillation
2 - 5 years:
  • lactic acidosis
  • renal failure acute
  • dehydration
  • gastrointestinal haemorrhage
  • anaemia
  • vomiting
  • diabetic ketoacidosis
  • diarrhoea
  • nausea
  • staphylococcal sepsis
5 - 10 years:
  • weight decreased
  • gastrointestinal haemorrhage
  • renal failure acute
  • hypoglycaemia
  • diarrhoea
  • nausea
  • constipation
  • upper gastrointestinal haemorrhage
  • anaemia
  • muscle spasms
10+ years:
  • diarrhoea
  • metabolic acidosis
  • renal failure acute
  • hypotension
  • syncope
  • renal impairment
  • hyperkalaemia
  • lactic acidosis
  • vomiting
  • renal failure
not specified:
  • nausea
  • dyspnoea
  • blood glucose increased
  • fatigue
  • diarrhoea
  • dizziness
  • pain
  • vomiting
  • weight decreased
  • drug ineffective

Most common drug interactions by gender *:

female:
  • nausea
  • blood glucose increased
  • diarrhoea
  • dyspnoea
  • vomiting
  • pain
  • fatigue
  • dizziness
  • weight decreased
  • asthenia
male:
  • dyspnoea
  • blood glucose increased
  • nausea
  • fatigue
  • diarrhoea
  • dizziness
  • weight decreased
  • myocardial infarction
  • pain
  • vomiting

Most common drug interactions by age *:

0-1:
  • neonatal respiratory distress syndrome
  • cerebrovascular accident
  • chest pain
  • congenital teratoma
  • conjunctival haemorrhage
  • cryptorchism
  • facial paresis
  • foetal cerebrovascular disorder
  • foetal growth restriction
  • hypoglycaemia neonatal
2-9:
  • myocardial infarction
  • accidental exposure
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • diarrhoea
  • nausea
  • abdominal distension
  • abdominal pain
  • abdominal pain upper
  • accident at work
10-19:
  • pain in extremity
  • dizziness
  • pruritus
  • cardiac disorder
  • weight decreased
  • erythema
  • body height decreased
  • diabetes mellitus
  • fatigue
  • headache
20-29:
  • deep vein thrombosis
  • nausea
  • pain
  • vomiting
  • dizziness
  • anxiety
  • gait disturbance
  • pulmonary embolism
  • abdominal pain
  • asthenia
30-39:
  • vomiting
  • pain
  • nausea
  • headache
  • diabetes mellitus
  • fatigue
  • abdominal pain
  • deep vein thrombosis
  • arthralgia
  • diarrhoea
40-49:
  • nausea
  • pain
  • dizziness
  • dyspnoea
  • chest pain
  • fatigue
  • diabetes mellitus
  • vomiting
  • diarrhoea
  • blood glucose increased
50-59:
  • nausea
  • blood glucose increased
  • vomiting
  • dizziness
  • pain
  • diarrhoea
  • dyspnoea
  • weight decreased
  • headache
  • fatigue
60+:
  • nausea
  • dyspnoea
  • diarrhoea
  • fatigue
  • blood glucose increased
  • renal failure acute
  • vomiting
  • dizziness
  • asthenia
  • weight decreased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Metformin and Aspirin?

Interactions between Metformin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Aspirin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Metformin (metformin hydrochloride) is often used to treat diabetes. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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