Review: taking Metformin and Nucynta er together


Summary

Drug interactions are reported among people who take Metformin and Nucynta er together. This review analyzes the effectiveness and drug interactions between Metformin and Nucynta er. It is created by eHealthMe based on reports of 136 people who take the same drugs from FDA and social media, and is updated regularly.

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Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

Nucynta Er

Nucynta er has active ingredients of tapentadol hydrochloride. It is often used in pain. (latest outcomes from Nucynta er 1,211 users)

On Sep, 24, 2016

136 people who take Metformin, Nucynta Er are studied.


Number of reports submitted per year:

Metformin and Nucynta er drug interactions.

Drug effectiveness over time:

Metformin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Nucynta Er:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Metformin:
  • female: 66.0% - (2 of 3 people)
  • male: 0.0% - (0 of 2 people)
Nucynta Er:
  • female: 66.0% - (2 of 3 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 0.0% - (0 of 2 people)
Nucynta Er:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • weight decreased
  • fall
  • serotonin syndrome
  • blindness transient
  • feeling abnormal
  • nausea
  • screaming
  • pollakiuria
  • vomiting
1 - 6 months:
  • fall
  • vertigo
  • accident
  • burning sensation
  • chills
  • diarrhoea
  • drug effect decreased
  • drug withdrawal syndrome
  • dysgraphia
  • hand fracture
6 - 12 months:
  • aggression
  • burning mouth syndrome
  • convulsion
  • discomfort
  • drug ineffective
  • dysarthria
  • dyskinesia
  • feeling abnormal
  • formication
  • impaired driving ability
1 - 2 years:
  • sweating - excessive
2 - 5 years:
  • anxiety
  • depression
  • anaemia
  • arrhythmia
  • back pain
  • diabetes mellitus
  • diabetic neuropathy
  • embolism arterial
  • hallucination
  • hyperhidrosis
5 - 10 years:
  • impaired gastric emptying
  • stress
  • weight gain
  • anxiety
  • back pain
  • blood pressure increased
  • diabetes mellitus
  • drug ineffective
  • glycosylated haemoglobin increased
  • headache
10+ years:
  • anaemia
  • pancytopenia
  • renal impairment
not specified:
  • gastrointestinal disorder
  • dyspnoea
  • chest pain
  • dizziness
  • hyperhidrosis
  • pain
  • drug ineffective
  • vision blurred
  • nausea
  • dehydration

Most common drug interactions by gender *:

female:
  • gastrointestinal disorder
  • fall
  • pain
  • nausea
  • dehydration
  • vomiting
  • drug ineffective
  • weight decreased
  • serotonin syndrome
  • blindness transient
male:
  • dyspnoea
  • hyperhidrosis
  • chest pain
  • dizziness
  • vision blurred
  • drug ineffective
  • pain
  • back pain
  • confusional state
  • nausea

Most common drug interactions by age *:

20-29:
  • aggression
  • convulsion
  • dysarthria
  • dyskinesia
  • incoherent
  • pain
30-39:
  • anxiety
  • nausea
  • back pain
  • depression
  • injury
  • deep vein thrombosis
  • diabetes mellitus
  • diabetic neuropathy
  • hyperhidrosis
  • hypertension
40-49:
  • pain
  • hyperhidrosis
  • accident
  • hand fracture
  • diarrhoea
  • burning sensation
  • chills
  • drug effect decreased
  • drug ineffective
  • drug withdrawal syndrome
50-59:
  • pain
  • fall
  • feeling abnormal
  • blindness transient
  • nausea
  • serotonin syndrome
  • weight decreased
  • drug ineffective
  • pollakiuria
  • screaming
60+:
  • gastrointestinal disorder
  • chest pain
  • dyspnoea
  • dizziness
  • dehydration
  • hyperhidrosis
  • vision blurred
  • presyncope
  • fall
  • drug screen positive

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Metformin (metformin hydrochloride) is often used to treat diabetes. Nucynta er (tapentadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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