Methadone hydrochloride and Topiramate drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Methadone hydrochloride and Topiramate together. This review analyzes the effectiveness and drug interactions between Methadone hydrochloride and Topiramate. It is created by eHealthMe based on reports of 420 people who take the same drugs from FDA, and is updated regularly.

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Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 3,317 users)

Topiramate

Topiramate has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topiramate 17,019 users)

On Feb, 24, 2017

420 people who take Methadone Hydrochloride, Topiramate are studied.


Number of reports submitted per year:

Methadone hydrochloride and Topiramate drug interactions.

Most common drug interactions over time *:

< 1 month:
  • disturbance in attention
  • urinary retention
  • amnesia
  • constipation
  • decreased appetite
  • drooling
  • drug effect decreased
  • drug withdrawal syndrome
  • dry mouth
  • dry skin
1 - 6 months:
  • depression
  • abnormal behaviour
  • dental caries
  • drug abuse
  • drug dependence
  • dysarthria
  • hypotension
  • partner stress
  • tooth abscess
  • arrested labour
6 - 12 months:
  • depression
  • abnormal behaviour
  • cardiac disorder
  • chest pain
  • dental caries
  • drug dependence
  • dysarthria
  • emotional disorder
  • pain
  • premature labour
1 - 2 years:
  • abnormal behaviour
  • dental caries
  • depression
  • drug dependence
  • dysarthria
  • tooth abscess
  • drug abuse
  • overdose
  • partner stress
  • tooth loss
2 - 5 years:
  • agitation
  • alcohol withdrawal syndrome
  • alcoholism
  • angiopathy
  • ankle fracture
  • appetite disorder
  • arthritis
  • back pain
  • balance disorder
  • blood glucose increased
5 - 10 years:
  • loss of consciousness
  • anxiety
  • bipolar disorder
  • convulsion
  • depression
10+ years:
  • back injury
  • hypertension
  • pre-existing condition improved
  • restless legs syndrome
  • sleep apnoea syndrome
  • therapeutic response unexpected
not specified:
  • pain
  • headache
  • convulsion
  • depression
  • fatigue
  • nausea
  • anxiety
  • confusional state
  • malaise
  • fall

Most common drug interactions by gender *:

female:
  • headache
  • depression
  • convulsion
  • fatigue
  • pain
  • nausea
  • pneumonia
  • chest pain
  • fall
  • anxiety
male:
  • pain
  • confusional state
  • vomiting
  • convulsion
  • malaise
  • headache
  • anxiety
  • depression
  • rash
  • drug toxicity

Most common drug interactions by age *:

2-9:
  • erythema multiforme
10-19:
  • depression
  • abnormal behaviour
  • activities of daily living impaired
  • alanine aminotransferase increased
  • anxiety
  • aspartate aminotransferase increased
  • bedridden
  • congenital pancreatic anomaly
  • drug effect decreased
  • drug ineffective
20-29:
  • pulmonary embolism
  • anxiety
  • injury
  • pain
  • anhedonia
  • cholecystitis acute
  • increased tendency to bruise
  • nephrolithiasis
  • attention deficit/hyperactivity disorder
  • back pain
30-39:
  • serotonin syndrome
  • completed suicide
  • cerebral vasoconstriction
  • drug toxicity
  • intentional overdose
  • loss of consciousness
  • subarachnoid haemorrhage
  • confusional state
  • neuropathy peripheral
  • type 2 diabetes mellitus
40-49:
  • pain
  • convulsion
  • headache
  • depression
  • malaise
  • nausea
  • anxiety
  • rash
  • drug dependence
  • vomiting
50-59:
  • depression
  • headache
  • fatigue
  • tremor
  • nausea
  • asthenia
  • convulsion
  • chest pain
  • balance disorder
  • central nervous system lesion
60+:
  • headache
  • myocardial infarction
  • deep vein thrombosis
  • pulmonary embolism
  • rectal haemorrhage
  • chest pain
  • constipation
  • diarrhoea
  • fatigue
  • feeling abnormal

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone hydrochloride and Topiramate?

Interactions between Methadone hydrochloride and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Topiramate and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Topiramate (topiramate) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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