Review: taking Methadone hydrochloride and Topiramate together


Summary

Drug interactions are reported among people who take Methadone hydrochloride and Topiramate together. This review analyzes the effectiveness and drug interactions between Methadone hydrochloride and Topiramate. It is created by eHealthMe based on reports of 362 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Methadone hydrochloride and Topiramate >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Methadone Hydrochloride

Methadone hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone hydrochloride 2,998 users)

Topiramate

Topiramate has active ingredients of topiramate. It is often used in epilepsy. (latest outcomes from Topiramate 11,194 users)

On Aug, 25, 2016

362 people who take Methadone Hydrochloride, Topiramate are studied.


Number of reports submitted per year:

Methadone hydrochloride and Topiramate drug interactions.

Drug effectiveness over time:

Methadone Hydrochloride:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 66.0% - (4 of 6 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 60.0% - (3 of 5 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Topiramate:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Methadone Hydrochloride:
  • female: 50.0% - (7 of 14 people)
  • male: 60.0% - (3 of 5 people)
Topiramate:
  • female: 25.0% - (3 of 12 people)
  • male: 80.0% - (4 of 5 people)

Drug effectiveness by age:

Methadone Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 71.0% - (5 of 7 people)
  • 40-49: 16.0% - (1 of 6 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 100.0% - (1 of 1 people)
Topiramate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 42.0% - (3 of 7 people)
  • 40-49: 60.0% - (3 of 5 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 100.0% - (1 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • disturbance in attention
  • urinary retention
  • amnesia
  • constipation
  • decreased appetite
  • drooling
  • drug effect decreased
  • drug withdrawal syndrome
  • dry mouth
  • dry skin
1 - 6 months:
  • depression
  • abnormal behaviour
  • dental caries
  • drug abuse
  • drug dependence
  • dysarthria
  • hypotension
  • partner stress
  • tooth abscess
  • arrested labour
6 - 12 months:
  • depression
  • abnormal behaviour
  • cardiac disorder
  • chest pain
  • dental caries
  • drug dependence
  • dysarthria
  • pain
  • tooth abscess
  • abdominal pain
1 - 2 years:
  • abnormal behaviour
  • dental caries
  • depression
  • drug dependence
  • dysarthria
  • tooth abscess
  • drug abuse
  • overdose
  • partner stress
  • tooth loss
2 - 5 years:
  • anxiety
  • dizziness
  • impaired memory
  • nausea
  • stomach discomfort
  • agitation
  • alcohol withdrawal syndrome
  • alcoholism
  • angiopathy
  • ankle fracture
5 - 10 years:
  • convulsion
  • decreased appetite
  • depression
  • anxiety
  • anger
  • depression suicidal
  • insomnia
  • nausea
  • bipolar disorder
  • constipation
10+ years:
  • anger
  • depression suicidal
  • insomnia
not specified:
  • convulsion
  • pain
  • headache
  • depression
  • fatigue
  • anxiety
  • nausea
  • confusional state
  • vomiting
  • fall

Most common drug interactions by gender *:

female:
  • convulsion
  • depression
  • headache
  • fatigue
  • nausea
  • anxiety
  • pneumonia
  • pain
  • fall
  • balance disorder
male:
  • pain
  • vomiting
  • confusional state
  • malaise
  • anxiety
  • convulsion
  • rash
  • depression
  • drug toxicity
  • headache

Most common drug interactions by age *:

2-9:
  • erythema multiforme
10-19:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • congenital pancreatic anomaly
  • depression
  • multiple injuries
  • pancreatic pseudocyst
  • pancreatitis
20-29:
  • pulmonary embolism
  • anxiety
  • anhedonia
  • cholecystitis acute
  • increased tendency to bruise
  • injury
  • nephrolithiasis
  • pain
  • attention deficit/hyperactivity disorder
  • cardiomegaly
30-39:
  • serotonin syndrome
  • completed suicide
  • cerebral vasoconstriction
  • drug toxicity
  • intentional overdose
  • loss of consciousness
  • subarachnoid haemorrhage
  • confusional state
  • neuropathy peripheral
  • type 2 diabetes mellitus
40-49:
  • pain
  • convulsion
  • headache
  • depression
  • malaise
  • anxiety
  • rash
  • drug dependence
  • nausea
  • vomiting
50-59:
  • depression
  • tremor
  • nausea
  • convulsion
  • headache
  • fatigue
  • asthenia
  • chest pain
  • balance disorder
  • central nervous system lesion
60+:
  • myocardial infarction
  • chest pain
  • constipation
  • diarrhoea
  • fatigue
  • feeling abnormal
  • pneumonia
  • anger
  • blood creatine phosphokinase increased
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone hydrochloride and Topiramate?

Can you answer these questions?

More questions for: Methadone hydrochloride, Topiramate

You may be interested in these reviews

More reviews for: Methadone hydrochloride, Topiramate

On eHealthMe, Methadone hydrochloride (methadone hydrochloride) is often used to treat pain. Topiramate (topiramate) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.